JP2022553824A5 - - Google Patents

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Publication number
JP2022553824A5
JP2022553824A5 JP2022525803A JP2022525803A JP2022553824A5 JP 2022553824 A5 JP2022553824 A5 JP 2022553824A5 JP 2022525803 A JP2022525803 A JP 2022525803A JP 2022525803 A JP2022525803 A JP 2022525803A JP 2022553824 A5 JP2022553824 A5 JP 2022553824A5
Authority
JP
Japan
Prior art keywords
nucleic acid
acid vector
vector according
transcription factor
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022525803A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022553824A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/058795 external-priority patent/WO2021091950A1/en
Publication of JP2022553824A publication Critical patent/JP2022553824A/ja
Publication of JP2022553824A5 publication Critical patent/JP2022553824A5/ja
Pending legal-status Critical Current

Links

JP2022525803A 2019-11-04 2020-11-04 前庭支持細胞プロモーター及びその使用 Pending JP2022553824A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962930520P 2019-11-04 2019-11-04
US62/930,520 2019-11-04
US202063024959P 2020-05-14 2020-05-14
US63/024,959 2020-05-14
PCT/US2020/058795 WO2021091950A1 (en) 2019-11-04 2020-11-04 Vestibular supporting cell promoters and uses thereof

Publications (2)

Publication Number Publication Date
JP2022553824A JP2022553824A (ja) 2022-12-26
JP2022553824A5 true JP2022553824A5 (https=) 2023-11-10

Family

ID=75848663

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022525803A Pending JP2022553824A (ja) 2019-11-04 2020-11-04 前庭支持細胞プロモーター及びその使用

Country Status (6)

Country Link
US (1) US20220331449A1 (https=)
EP (1) EP4076467A4 (https=)
JP (1) JP2022553824A (https=)
CN (2) CN119391775A (https=)
TW (1) TWI902721B (https=)
WO (1) WO2021091950A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220054640A1 (en) * 2018-12-11 2022-02-24 Decibel Therapeutics, Inc. Compositions and methods for the delivery of therapeutic agents across the round window membrane
CN118043468A (zh) * 2021-06-11 2024-05-14 分贝治疗公司 用于内耳中的细胞类型特异性基因表达的组合物和方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002082904A2 (en) * 2001-04-13 2002-10-24 The Trustees Of The University Of Pennsylvania Method of treating or retarding the development of blindness
US20070161031A1 (en) * 2005-12-16 2007-07-12 The Board Of Trustees Of The Leland Stanford Junior University Functional arrays for high throughput characterization of gene expression regulatory elements
WO2008076556A2 (en) * 2006-11-15 2008-06-26 Massachusetts Eye & Ear Infirmary Generation of inner ear cells
WO2009108274A2 (en) * 2008-02-26 2009-09-03 The University Of North Carolina At Chapel Hill Methods and compositions for adeno-associated virus (aav) with hi loop mutations
WO2012149038A1 (en) * 2011-04-25 2012-11-01 Advanced Bioscience Laboratories, Inc. Truncated hiv envelope proteins (env), methods and compositions related thereto
MX367100B (es) * 2012-02-17 2019-08-05 The Children´S Hospital Of Philadelphia Composiciones del vector aav y metodos para su transferencia genetica a celulas, organos y tejidos.
US20140024663A1 (en) * 2012-07-17 2014-01-23 Georgia Health Sciences University Research Institute, Inc. Atb(0,+) amino acid transporter as a drug target for treatment of estrogen receptor-positive breast cancer
US20150209406A1 (en) * 2012-09-07 2015-07-30 Massachusetts Eye And Ear Infirmary Methods and compositions for regenerating hair cells and/or supporting cells
US20160298080A1 (en) * 2013-12-03 2016-10-13 The Johns Hopkins University Method for highly efficient conversion of human stem cells to lineage-specific neurons
SG10201913266UA (en) * 2015-12-11 2020-02-27 Massachusetts Eye & Ear Infirmary Materials and methods for delivering nucleic acids to cochlear and vestibular cells
EP3407901B1 (en) * 2016-01-29 2021-07-21 Massachusetts Eye & Ear Infirmary Expansion and differentiation of inner ear supporting cells and methods of use thereof
US11191847B2 (en) * 2016-04-15 2021-12-07 The Trustees Of The University Of Pennsylvania Gene therapy for treating hemophilia B
WO2018145111A1 (en) * 2017-02-06 2018-08-09 Children's Medical Center Corporation Materials and methods for delivering nucleic acids to cochlear and vestibular cells
US20190345516A1 (en) * 2018-03-12 2019-11-14 Musc Foundation For Research Development Methods for treating eye disease

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