JP2023119042A5 - - Google Patents
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- JP2023119042A5 JP2023119042A5 JP2023113057A JP2023113057A JP2023119042A5 JP 2023119042 A5 JP2023119042 A5 JP 2023119042A5 JP 2023113057 A JP2023113057 A JP 2023113057A JP 2023113057 A JP2023113057 A JP 2023113057A JP 2023119042 A5 JP2023119042 A5 JP 2023119042A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- alkyl
- compound
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025034943A JP2025078783A (ja) | 2017-12-22 | 2025-03-05 | Ｃｎｓ障害の処置のための組成物および方法 |
Applications Claiming Priority (20)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762610067P | 2017-12-22 | 2017-12-22 | |
| US62/610,067 | 2017-12-22 | ||
| US201762612070P | 2017-12-29 | 2017-12-29 | |
| US201762611977P | 2017-12-29 | 2017-12-29 | |
| US201762612067P | 2017-12-29 | 2017-12-29 | |
| US201762612164P | 2017-12-29 | 2017-12-29 | |
| US62/612,164 | 2017-12-29 | ||
| US62/611,977 | 2017-12-29 | ||
| US62/612,067 | 2017-12-29 | ||
| US62/612,070 | 2017-12-29 | ||
| US201862765164P | 2018-08-17 | 2018-08-17 | |
| US62/765,164 | 2018-08-17 | ||
| US201862728499P | 2018-09-07 | 2018-09-07 | |
| US62/728,499 | 2018-09-07 | ||
| US201862737559P | 2018-09-27 | 2018-09-27 | |
| US62/737,559 | 2018-09-27 | ||
| US201862754977P | 2018-11-02 | 2018-11-02 | |
| US62/754,977 | 2018-11-02 | ||
| JP2020534302A JP2021506904A (ja) | 2017-12-22 | 2018-12-21 | Ｃｎｓ障害の処置のための組成物および方法 |
| PCT/US2018/067306 WO2019126761A1 (en) | 2017-12-22 | 2018-12-21 | Compositions and methods for treating cns disorders |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020534302A Division JP2021506904A (ja) | 2017-12-22 | 2018-12-21 | Ｃｎｓ障害の処置のための組成物および方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025034943A Division JP2025078783A (ja) | 2017-12-22 | 2025-03-05 | Ｃｎｓ障害の処置のための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023119042A JP2023119042A (ja) | 2023-08-25 |
| JP2023119042A5 true JP2023119042A5 (https=) | 2025-03-14 |
| JP7689160B2 JP7689160B2 (ja) | 2025-06-05 |
Family
ID=65234664
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020534302A Withdrawn JP2021506904A (ja) | 2017-12-22 | 2018-12-21 | Ｃｎｓ障害の処置のための組成物および方法 |
| JP2023113057A Active JP7689160B2 (ja) | 2017-12-22 | 2023-07-10 | Ｃｎｓ障害の処置のための組成物および方法 |
| JP2025034943A Pending JP2025078783A (ja) | 2017-12-22 | 2025-03-05 | Ｃｎｓ障害の処置のための組成物および方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020534302A Withdrawn JP2021506904A (ja) | 2017-12-22 | 2018-12-21 | Ｃｎｓ障害の処置のための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025034943A Pending JP2025078783A (ja) | 2017-12-22 | 2025-03-05 | Ｃｎｓ障害の処置のための組成物および方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20220315621A1 (https=) |
| EP (1) | EP3728285B1 (https=) |
| JP (3) | JP2021506904A (https=) |
| KR (1) | KR20200104349A (https=) |
| CN (3) | CN111741965B (https=) |
| AR (1) | AR114044A1 (https=) |
| AU (2) | AU2018392093B2 (https=) |
| BR (1) | BR112020012761A2 (https=) |
| CA (1) | CA3086189A1 (https=) |
| IL (2) | IL275506A (https=) |
| MA (1) | MA51316A (https=) |
| MX (3) | MX2020006608A (https=) |
| TW (1) | TWI907333B (https=) |
| WO (1) | WO2019126761A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201606063RA (en) | 2012-01-23 | 2016-09-29 | Sage Therapeutics Inc | Neuroactive steroid formulations and methods of treating cns disorders |
| MX2015002252A (es) | 2012-08-21 | 2015-07-21 | Sage Therapeutics Inc | Metodos para tratar epilepsia o estado de epilepsia. |
| JP6470258B2 (ja) | 2013-04-17 | 2019-02-13 | セージ セラピューティクス， インコーポレイテッド | １９−ノルｃ３，３−ジ置換ｃ２１−ｎ−ピラゾリルステロイドおよびその使用方法 |
| WO2015195962A1 (en) | 2014-06-18 | 2015-12-23 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| JOP20200195A1 (ar) | 2014-09-08 | 2017-06-16 | Sage Therapeutics Inc | سترويدات وتركيبات نشطة عصبياً، واستخداماتها |
| WO2016082789A1 (en) | 2014-11-27 | 2016-06-02 | Sage Therapeutics, Inc. | Compositions and methods for treating cns disorders |
| TWI904593B (zh) | 2016-08-23 | 2025-11-11 | 美商賽吉醫療公司 | 結晶19-去甲c3,3-二取代之c21-n-吡唑類固醇 |
| EP3720867A1 (en) | 2017-12-08 | 2020-10-14 | Sage Therapeutics, Inc. | Deuterated 21 -[4-cyano-pyrazol-1 -yl]-19-nor-pregan-3. alpha-ol-20-one derivatives for treating cns disorders |
| CN111741965B (zh) | 2017-12-22 | 2024-06-25 | 萨奇治疗股份有限公司 | 治疗中枢神经系统疾病的组合物和方法 |
| MA51568A (fr) | 2018-01-12 | 2021-04-21 | Sage Therapeutics Inc | Composés aza-, oxa et thia-pregnan-20-one-3.alpha.-ol s'utilisant dans le traitement de troubles du système nerveux central |
| EP3750909B1 (en) * | 2018-02-11 | 2025-03-05 | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. | Steroid derivative regulators, method for preparing the same, and uses thereof |
| CN113166193B (zh) | 2018-10-12 | 2025-08-19 | 萨奇治疗股份有限公司 | 用于治疗cns病症的在位置10处被环状基团取代的神经活性类固醇 |
| IL283629B2 (en) | 2018-12-05 | 2026-03-01 | Sage Therapeutics Inc | Neuroactive steroids and methods of using them |
| CN116589521B (zh) * | 2019-01-08 | 2025-07-11 | 成都康弘药业集团股份有限公司 | 甾体类化合物、用途及其制备方法 |
| CR20240234A (es) | 2019-05-31 | 2024-07-09 | Sage Therapeutics Inc | ESTEROIDES NEUROACTIVOS Y COMPOSICIONES DE ESTOS (Divisional 2021-629) |
| AU2020304673A1 (en) * | 2019-06-27 | 2022-01-20 | Sage Therapeutics, Inc. | Compositions and methods for treating CNS disorders |
| US20230257415A1 (en) | 2019-06-27 | 2023-08-17 | Sage Therapeutics, Inc. | Compounds for treating cns disorders |
| JP7787635B2 (ja) * | 2019-06-27 | 2025-12-17 | セージ セラピューティクス， エルエルシー | Ｃｎｓ障害を治療するための組成物及び方法 |
| US10857163B1 (en) | 2019-09-30 | 2020-12-08 | Athenen Therapeutics, Inc. | Compositions that preferentially potentiate subtypes of GABAA receptors and methods of use thereof |
| WO2022246634A1 (en) * | 2021-05-25 | 2022-12-01 | Zhejiang Jiachi Development Pharmaceuticals Ltd. | Compositions for treating insomnia and uses thereof |
| EP4725951A1 (en) * | 2023-07-14 | 2026-04-15 | Chengdu Kanghong Pharmaceutical Co., Ltd. | Crystal form of steroid compound and use thereof |
| CN119529013B (zh) * | 2024-11-25 | 2025-11-07 | 湖南新合新生物医药有限公司 | 一种祖拉诺龙中间体的合成方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1380246A (en) * | 1970-12-17 | 1975-01-08 | Glaxo Lab Ltd | 3alpha-hydroxy-androstanes and esters thereof |
| DE2445161A1 (de) * | 1974-09-19 | 1976-04-01 | Schering Ag | D-homo-20-ketopregnane ii |
| ES432106A1 (es) * | 1973-11-30 | 1976-11-01 | Schering Ag | Procedimiento para la preparacion de d-homo-20-cetopregna- nos. |
| IL48628A0 (en) * | 1974-12-23 | 1976-02-29 | Schering Ag | D-homo-20-keto-pregnanes and process for their manufactur |
| GB1570394A (en) * | 1976-01-06 | 1980-07-02 | Glaxo Lab Ltd | 11-acyloxy-3-hydroxy steroids |
| GB1581234A (en) * | 1976-04-05 | 1980-12-10 | Glaxo Operations Ltd | 11a - amino - 3a - hydroxysteroids |
| GB1581235A (en) * | 1977-04-04 | 1980-12-10 | Glaxo Operations Ltd | 11a-amino-3a-hydroxy-steroids |
| US5028631A (en) | 1987-11-25 | 1991-07-02 | Schwartz Arthur G | Homoandrostan-17-one and homoandrosten-17-ones |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| DE19581854T1 (de) | 1994-12-03 | 1997-12-04 | Dong Kook Pharmaceutical Co | Asiatsäure-Derivate, Verfahren zu ihrer Herstellung und sie enthaltendes dermatologisches Agens |
| AU3967297A (en) * | 1996-08-01 | 1998-02-25 | Cocensys, Inc. | Use of gaba and nmda receptor ligands for the treatment of migraine headache |
| AU2001294959A1 (en) | 2000-09-29 | 2002-04-08 | Robert M. Carlson | Triterpenes having antibacterial activity |
| JP6470258B2 (ja) * | 2013-04-17 | 2019-02-13 | セージ セラピューティクス， インコーポレイテッド | １９−ノルｃ３，３−ジ置換ｃ２１−ｎ−ピラゾリルステロイドおよびその使用方法 |
| US10577390B2 (en) | 2014-10-16 | 2020-03-03 | Sage Therapeutics, Inc. | Compositions and methods for treating CNS disorders |
| CN111741965B (zh) | 2017-12-22 | 2024-06-25 | 萨奇治疗股份有限公司 | 治疗中枢神经系统疾病的组合物和方法 |
| CN116589521B (zh) | 2019-01-08 | 2025-07-11 | 成都康弘药业集团股份有限公司 | 甾体类化合物、用途及其制备方法 |
| AU2020304673A1 (en) | 2019-06-27 | 2022-01-20 | Sage Therapeutics, Inc. | Compositions and methods for treating CNS disorders |
-
2018
- 2018-12-21 CN CN201880089891.9A patent/CN111741965B/zh active Active
- 2018-12-21 CN CN202410737964.8A patent/CN118772223A/zh active Pending
- 2018-12-21 AU AU2018392093A patent/AU2018392093B2/en active Active
- 2018-12-21 US US16/955,736 patent/US20220315621A1/en not_active Abandoned
- 2018-12-21 BR BR112020012761-2A patent/BR112020012761A2/pt unknown
- 2018-12-21 CA CA3086189A patent/CA3086189A1/en active Pending
- 2018-12-21 JP JP2020534302A patent/JP2021506904A/ja not_active Withdrawn
- 2018-12-21 WO PCT/US2018/067306 patent/WO2019126761A1/en not_active Ceased
- 2018-12-21 MX MX2020006608A patent/MX2020006608A/es unknown
- 2018-12-21 AR ARP180103829A patent/AR114044A1/es unknown
- 2018-12-21 KR KR1020207021155A patent/KR20200104349A/ko not_active Ceased
- 2018-12-21 CN CN202410098394.2A patent/CN118085004A/zh active Pending
- 2018-12-21 MA MA051316A patent/MA51316A/fr unknown
- 2018-12-21 EP EP18839992.7A patent/EP3728285B1/en active Active
- 2018-12-22 TW TW107146684A patent/TWI907333B/zh active
-
2020
- 2020-06-18 IL IL275506A patent/IL275506A/en unknown
- 2020-07-13 MX MX2023002004A patent/MX2023002004A/es unknown
- 2020-07-13 MX MX2023002006A patent/MX2023002006A/es unknown
-
2023
- 2023-07-10 JP JP2023113057A patent/JP7689160B2/ja active Active
- 2023-12-22 AU AU2023285947A patent/AU2023285947A1/en not_active Abandoned
-
2024
- 2024-07-12 US US18/771,262 patent/US20250171492A1/en active Pending
-
2025
- 2025-03-05 JP JP2025034943A patent/JP2025078783A/ja active Pending
- 2025-10-05 IL IL323780A patent/IL323780A/en unknown
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