JP2022553833A - エストロゲン受容体調節薬の塩及び形態 - Google Patents

エストロゲン受容体調節薬の塩及び形態 Download PDF

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JP2022553833A
JP2022553833A JP2022525923A JP2022525923A JP2022553833A JP 2022553833 A JP2022553833 A JP 2022553833A JP 2022525923 A JP2022525923 A JP 2022525923A JP 2022525923 A JP2022525923 A JP 2022525923A JP 2022553833 A JP2022553833 A JP 2022553833A
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pharmaceutically acceptable
acceptable salt
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JP2022553833A5 (enExample
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キンファ ファン，ピーター
ガジャナン ヘグデ，サイー
デュアン バンカー，ケビン
ナイト，ジョン
ヘレン スリー，デボラ
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リキュリウム アイピー ホールディングス リミテッド ライアビリティー カンパニー
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Publication of JP2022553833A publication Critical patent/JP2022553833A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2022525923A 2019-11-04 2020-11-02 エストロゲン受容体調節薬の塩及び形態 Pending JP2022553833A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962930153P 2019-11-04 2019-11-04
US62/930,153 2019-11-04
PCT/US2020/058526 WO2021091819A1 (en) 2019-11-04 2020-11-02 Salts and forms of an estrogen receptor modulator

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JP2022553833A true JP2022553833A (ja) 2022-12-26
JP2022553833A5 JP2022553833A5 (enExample) 2023-11-13

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JP2022525923A Pending JP2022553833A (ja) 2019-11-04 2020-11-02 エストロゲン受容体調節薬の塩及び形態

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US (1) US20220389006A1 (enExample)
EP (1) EP4045507A4 (enExample)
JP (1) JP2022553833A (enExample)
KR (1) KR20220103977A (enExample)
CN (1) CN114945570A (enExample)
AU (1) AU2020380211A1 (enExample)
BR (1) BR112022008520A2 (enExample)
CA (1) CA3159749A1 (enExample)
IL (1) IL292680A (enExample)
MX (1) MX2022005139A (enExample)
TW (1) TW202132294A (enExample)
WO (1) WO2021091819A1 (enExample)

Families Citing this family (3)

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Publication number Priority date Publication date Assignee Title
DK3847157T3 (da) * 2018-09-07 2022-08-08 Sanofi Sa Fremgangsmåde til fremstilling af methyl-[6-(2,4-dichlorphenyl)-5-[4-[(3s)-1-(3-fluorpropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7h-benzo[7]annulen-2-carboxylat] og salt deraf
EP3978493A4 (en) * 2019-05-24 2023-02-01 Zhejiang Hisun Pharmaceutical Co., Ltd. CRYSTALLINE FORMS OF ACRYLIC ACID DERIVATIVES, METHOD OF MANUFACTURE THEREOF AND USE THEREOF
EP4267578A4 (en) 2020-12-23 2024-11-20 Recurium IP Holdings, LLC ESTROGEN RECEPTOR MODULATORS

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019515026A (ja) * 2016-04-01 2019-06-06 ゼノ ロイアルティー アンド マイルストーンズ リミテッド ライアビリティー カンパニー エストロゲン受容体調節薬

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201028414A (en) * 2009-01-16 2010-08-01 Merck Sharp & Dohme Oxadiazole beta carboline derivatives as antidiabetic compounds
AP2015008858A0 (en) * 2013-05-28 2015-11-30 Astrazeneca Ab Chemical compounds
EP4121413A4 (en) * 2020-04-22 2024-04-17 Recurium IP Holdings, LLC PREPARATION OF A SELECTIVE ESTROGEN RECEPTOR DEGRADING AGENT

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019515026A (ja) * 2016-04-01 2019-06-06 ゼノ ロイアルティー アンド マイルストーンズ リミテッド ライアビリティー カンパニー エストロゲン受容体調節薬

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 66, no. 1, JPN6014023656, 1977, pages 1 - 19, ISSN: 0005557793 *
浅原 照三, 溶剤ハンドブック, JPN6011026738, 1985, pages 47 - 51, ISSN: 0005557795 *
長瀬博監訳, 最新 創薬化学 下巻, JPN6008054607, 25 September 1999 (1999-09-25), pages 347 - 365, ISSN: 0005557792 *
高田則幸: "創薬段階における原薬Formスクリーニングと選択", PHARM STAGE, vol. 6, no. 10, JPN6009053755, 15 January 2007 (2007-01-15), pages 20 - 25, ISSN: 0005557794 *

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MX2022005139A (es) 2022-06-24
TW202132294A (zh) 2021-09-01
CA3159749A1 (en) 2021-05-14
US20220389006A1 (en) 2022-12-08
WO2021091819A1 (en) 2021-05-14
KR20220103977A (ko) 2022-07-25
AU2020380211A1 (en) 2022-05-19
IL292680A (en) 2022-07-01
EP4045507A1 (en) 2022-08-24
EP4045507A4 (en) 2023-11-01
BR112022008520A2 (pt) 2022-07-26
CN114945570A (zh) 2022-08-26

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