JP2022552401A5 - - Google Patents
Info
- Publication number
- JP2022552401A5 JP2022552401A5 JP2022522773A JP2022522773A JP2022552401A5 JP 2022552401 A5 JP2022552401 A5 JP 2022552401A5 JP 2022522773 A JP2022522773 A JP 2022522773A JP 2022522773 A JP2022522773 A JP 2022522773A JP 2022552401 A5 JP2022552401 A5 JP 2022552401A5
- Authority
- JP
- Japan
- Prior art keywords
- piperidine
- imidazole
- propan
- methylthio
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2019111690 | 2019-10-17 | ||
| CNPCT/CN2019/111690 | 2019-10-17 | ||
| PCT/EP2020/079009 WO2021074281A1 (en) | 2019-10-17 | 2020-10-15 | Substituted azacyles as trmp8 modulators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022552401A JP2022552401A (ja) | 2022-12-15 |
| JP2022552401A5 true JP2022552401A5 (enExample) | 2023-10-24 |
| JP7778688B2 JP7778688B2 (ja) | 2025-12-02 |
Family
ID=72964655
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022522773A Active JP7778688B2 (ja) | 2019-10-17 | 2020-10-15 | Ｔｒｍｐ８モジュレーターとしての置換アザシル |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US12528801B2 (enExample) |
| EP (1) | EP4045491A1 (enExample) |
| JP (1) | JP7778688B2 (enExample) |
| KR (1) | KR20220085798A (enExample) |
| CN (1) | CN114555594B (enExample) |
| BR (1) | BR112022005289A2 (enExample) |
| CO (1) | CO2022004130A2 (enExample) |
| IL (1) | IL292156B2 (enExample) |
| MX (1) | MX2022003494A (enExample) |
| WO (1) | WO2021074281A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202012170D0 (en) * | 2020-08-05 | 2020-09-16 | Givaudan Sa | Organic compounds |
| GB202013383D0 (en) * | 2020-08-26 | 2020-10-07 | Givaudan Sa | Process |
| WO2022170519A1 (en) | 2021-02-09 | 2022-08-18 | Givaudan Sa | Organic compounds |
| GB202102676D0 (en) | 2021-02-25 | 2021-04-14 | Givaudan Sa | Compositions |
| GB202103207D0 (en) | 2021-03-08 | 2021-04-21 | Givaudan Sa | Organic compounds |
| GB202105661D0 (en) | 2021-04-21 | 2021-06-02 | Givaudan Sa | Organic compounds |
| US20240238183A1 (en) | 2021-05-28 | 2024-07-18 | Firmenich Incorporated | Compositions that enhance the cooling effect |
| CN117813077A (zh) * | 2021-08-16 | 2024-04-02 | 西姆莱斯股份公司 | 组合物 |
| US20250387310A1 (en) | 2022-07-07 | 2025-12-25 | Firmenich Incorporated | Compositions that enhance the cooling effect |
| EP4554572A2 (en) | 2022-07-11 | 2025-05-21 | Symrise AG | Mixtures and uses of (2e)-3-(1,3-benzodioxol-5-yl)-n-phenyl-n-(tetrahydro-3-furanyl)-2-propenamide |
| JP2026512978A (ja) | 2022-10-27 | 2026-04-22 | フイルメニツヒ ソシエテ アノニム | フラボノイド組成物およびその使用 |
| US20260206810A1 (en) | 2022-12-22 | 2026-07-23 | Firmenich Sa | Natural sweetener compositions and uses thereof |
| US20260206809A1 (en) | 2022-12-22 | 2026-07-23 | Firmenich Sa | Natural sweetener compositions containing alkyl lactates and uses thereof |
| JP2026511252A (ja) | 2023-03-28 | 2026-04-10 | フイルメニツヒ ソシエテ アノニム | 味改変組成物およびその使用 |
| EP4774272A1 (en) | 2023-09-04 | 2026-07-15 | Symrise AG | Trpm8 modulators and related method for modulating trpm8 receptors |
| GB202315636D0 (en) | 2023-10-12 | 2023-11-29 | Givaudan Sa | Composition |
| WO2025132323A1 (en) | 2023-12-21 | 2025-06-26 | Dsm-Firmenich Ag | Compositions comprising a sunscreen active agent |
| WO2026052684A1 (en) | 2024-09-04 | 2026-03-12 | Givaudan Sa | Flavour compositions |
| WO2026087386A1 (en) | 2024-10-24 | 2026-04-30 | Firmenich Sa | Rosin diester compounds and uses thereof |
| WO2026092819A1 (en) | 2024-10-28 | 2026-05-07 | Symrise Ag | Oral care compositions |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3988433A (en) | 1973-08-10 | 1976-10-26 | The Procter & Gamble Company | Oral compositions for preventing or removing stains from teeth |
| US4083955A (en) | 1975-04-02 | 1978-04-11 | The Procter & Gamble Company | Processes and compositions for remineralization of dental enamel |
| US4528180A (en) | 1983-03-01 | 1985-07-09 | Schaeffer Hans A | Dental preparation, article and method for storage and delivery thereof |
| US4849213A (en) | 1983-03-01 | 1989-07-18 | Schaeffer Hans A | Dental preparation, article and method for storage and delivery therof |
| US5198220A (en) | 1989-11-17 | 1993-03-30 | The Procter & Gamble Company | Sustained release compositions for treating periodontal disease |
| US5145666A (en) | 1991-10-23 | 1992-09-08 | The Proctor & Gamble Co. | Methods of reducing plaque and gingivitis with reduced staining |
| US5213790A (en) | 1991-10-23 | 1993-05-25 | The Procter & Gamble Co. | Methods of reducing plaque and gingivitis with reduced staining |
| US5281410A (en) | 1991-10-23 | 1994-01-25 | The Proctor & Gamble Company | Methods of reducing plaque and gingivitis with reduced staining |
| US5242910A (en) | 1992-10-13 | 1993-09-07 | The Procter & Gamble Company | Sustained release compositions for treating periodontal disease |
| US5965537A (en) * | 1997-03-10 | 1999-10-12 | Basf Aktiengesellschaft | Dolastatin 15 derivatives with carbonyl and heterocyclic functionalities at the C-terminus |
| AU2479702A (en) * | 2000-10-30 | 2002-05-15 | Janssen Pharmaceutica Nv | Tripeptidyl peptidase inhibitors |
| HUP0500921A2 (en) | 2005-10-05 | 2007-07-30 | Richter Gedeon Nyrt | Tetrazole derivatives, process for their preparation and their use |
| HUP0500920A2 (en) * | 2005-10-05 | 2007-07-30 | Richter Gedeon Nyrt | Oxadiazole derivatives, process for their preparation and their use |
| GB0704163D0 (en) | 2007-03-02 | 2007-04-11 | Quest Int Serv Bv | Compositions comprising a physiological coolant |
| EP2331499B1 (en) * | 2008-08-19 | 2016-09-21 | Janssen Pharmaceutica NV | Cold menthol receptor antagonists |
| AU2009318056B2 (en) | 2008-11-20 | 2014-07-24 | The Procter & Gamble Company | Personal care compositions providing enhanced cooling sensation |
| CN103201279A (zh) | 2010-11-05 | 2013-07-10 | 赛诺米克斯公司 | 作为trpm8的调节剂有用的化合物 |
| WO2014037340A1 (de) | 2012-09-05 | 2014-03-13 | Bayer Cropscience Ag | Verwendung substituierter 2-amidobenzimidazole, 2-amidobenzoxazole und 2-amidobenzothiazole oder deren salze als wirkstoffe gegen abiotischen pflanzenstress |
| CN106103416B (zh) | 2014-03-14 | 2021-03-02 | 拉夸里亚创药株式会社 | 作为trpm8拮抗剂的氮杂螺衍生物 |
| MY195177A (en) * | 2015-06-23 | 2023-01-11 | Kissei Pharmaceutical | Pyrazole Derivative or Pharmaceutically Acceptable Salt Thereof |
| EP3675809B1 (de) | 2017-08-31 | 2023-09-27 | Basf Se | Verwendung physiologischer kühlwirkstoffe und mittel enthaltend solche wirkstoffe |
| EP3658109B1 (en) | 2017-12-21 | 2022-12-07 | Firmenich SA | Cooling and flavor boosting compositions |
-
2020
- 2020-10-15 IL IL292156A patent/IL292156B2/en unknown
- 2020-10-15 BR BR112022005289A patent/BR112022005289A2/pt unknown
- 2020-10-15 US US17/769,198 patent/US12528801B2/en active Active
- 2020-10-15 CN CN202080072667.6A patent/CN114555594B/zh active Active
- 2020-10-15 EP EP20793607.1A patent/EP4045491A1/en active Pending
- 2020-10-15 MX MX2022003494A patent/MX2022003494A/es unknown
- 2020-10-15 KR KR1020227016597A patent/KR20220085798A/ko active Pending
- 2020-10-15 JP JP2022522773A patent/JP7778688B2/ja active Active
- 2020-10-15 WO PCT/EP2020/079009 patent/WO2021074281A1/en not_active Ceased
-
2022
- 2022-03-31 CO CONC2022/0004130A patent/CO2022004130A2/es unknown
-
2025
- 2025-12-15 US US19/419,870 patent/US20260103459A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN114555594B (zh) | 作为trmp8调节剂的取代的氮杂环 | |
| DE69517333T2 (de) | Substituierte biphenyl-verbindungen zur behandlung von entzündung | |
| RU2454415C9 (ru) | Производное индола | |
| RU2361860C2 (ru) | Новые замещенные 3-сера-индолы | |
| RU2309953C2 (ru) | Арил- и гетероарилзамещенные тетрагидроизохинолины, фармацевтическая композиция и способ лечения на их основе | |
| MXPA01010312A (es) | Derivados de 4,5-diaril-3/2h)-furanona como inhibidores de ciclooxigenasa 2. | |
| RU2455288C2 (ru) | Соединения и композиции 5-(4-(галогеналкокси)фенил)пиримидин-2-амина в качестве ингибиторов киназ | |
| RU2312105C2 (ru) | N-пиразинилфенилсульфонамиды и их применение при лечении опосредованных хемокинами заболеваний | |
| US6699884B2 (en) | Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation | |
| JP2005533004A5 (enExample) | ||
| JP2010533715A5 (enExample) | ||
| EP1125932A2 (en) | Substituted thiazoles for the treatment of inflammation | |
| JP2006503081A5 (enExample) | ||
| JPH11503722A (ja) | 炎症の治療のための置換イソオキサゾール | |
| RU2014114120A (ru) | Производные бензойной кислоты в качестве ингибиторов эукариотического фактора инициации трансляции 4е | |
| RU2005136368A (ru) | Производные пиперазина и их применение для лечения неврологических и психиатрических заболеваний | |
| LV12239B (en) | Substituted benzenesulfonamide derivatives as prodrugs of cox-2 inhibitors | |
| JP2006517572A5 (enExample) | ||
| JP2007500226A5 (enExample) | ||
| JP2008546836A (ja) | 新規な用途 | |
| WO1995030656A1 (en) | Substituted cyclopentadienyl compounds for the treatment of inflammation | |
| RU2016129018A (ru) | Производные оксиндола, их получение и терапевтическое применение при лечении заболеваний, связанных с амрк | |
| PT1684750E (pt) | Compostos 2-aminoariloxazol como inibidores de tirosina cinases | |
| JP2008545686A5 (enExample) | ||
| JP2003531201A (ja) | 炎症を治療するための２−フルオロベンゼンスルホニル化合物 |