JP2022552015A5 - - Google Patents
Info
- Publication number
- JP2022552015A5 JP2022552015A5 JP2022523048A JP2022523048A JP2022552015A5 JP 2022552015 A5 JP2022552015 A5 JP 2022552015A5 JP 2022523048 A JP2022523048 A JP 2022523048A JP 2022523048 A JP2022523048 A JP 2022523048A JP 2022552015 A5 JP2022552015 A5 JP 2022552015A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- syndrome
- hearing loss
- composition
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025127052A JP2025163105A (ja) | 2019-10-18 | 2025-07-30 | 蝸牛細胞を標的とする遺伝子治療 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962923398P | 2019-10-18 | 2019-10-18 | |
| US62/923,398 | 2019-10-18 | ||
| PCT/US2020/056385 WO2021077115A1 (en) | 2019-10-18 | 2020-10-19 | Gene therapy targeting cochlear cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025127052A Division JP2025163105A (ja) | 2019-10-18 | 2025-07-30 | 蝸牛細胞を標的とする遺伝子治療 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022552015A JP2022552015A (ja) | 2022-12-14 |
| JP2022552015A5 true JP2022552015A5 (https=) | 2023-10-20 |
| JP7792900B2 JP7792900B2 (ja) | 2025-12-26 |
Family
ID=73288705
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022523048A Active JP7792900B2 (ja) | 2019-10-18 | 2020-10-19 | 蝸牛細胞を標的とする遺伝子治療 |
| JP2025127052A Pending JP2025163105A (ja) | 2019-10-18 | 2025-07-30 | 蝸牛細胞を標的とする遺伝子治療 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025127052A Pending JP2025163105A (ja) | 2019-10-18 | 2025-07-30 | 蝸牛細胞を標的とする遺伝子治療 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220378945A1 (https=) |
| EP (1) | EP4045092A1 (https=) |
| JP (2) | JP7792900B2 (https=) |
| AU (1) | AU2020366531A1 (https=) |
| CA (1) | CA3158286A1 (https=) |
| WO (1) | WO2021077115A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20220157944A (ko) | 2020-02-21 | 2022-11-29 | 아카우오스, 인크. | 인간 대상체에서 비-연령-연관 청각 장애를 치료하기 위한 조성물 및 방법 |
| US12497612B2 (en) | 2020-03-09 | 2025-12-16 | University Of Massachusetts | Gene replacement therapy for FOXG1 syndrome |
| EP4330413A4 (en) * | 2021-04-27 | 2026-01-28 | Childrens Hospital Philadelphia | Adeno-associated viral vectors for cochlear transduction |
| US20250073354A1 (en) * | 2021-12-23 | 2025-03-06 | University Of Rochester | Compositions and methods for delivery of agents to inner ear |
| WO2023230562A2 (en) * | 2022-05-26 | 2023-11-30 | Board Of Regents Of The University Ofnebraska | Rna compositions and therapeutic methods thereof |
| WO2024064608A2 (en) * | 2022-09-20 | 2024-03-28 | Intergalactic Therapeutics, Inc. | Best1 vectors and uses thereof |
| JP2026501619A (ja) * | 2022-12-30 | 2026-01-16 | アーボーメッド・カンパニー・リミテッド | 薬学的活性化合物、組成物、およびペンドリン調節方法 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5173414A (en) | 1990-10-30 | 1992-12-22 | Applied Immune Sciences, Inc. | Production of recombinant adeno-associated virus vectors |
| PT728214E (pt) | 1993-11-09 | 2004-11-30 | Ohio Med College | Linhas celulares estaveis capazes de expressar o gene de replicacao do virus adeno-associado |
| WO1995013365A1 (en) | 1993-11-09 | 1995-05-18 | Targeted Genetics Corporation | Generation of high titers of recombinant aav vectors |
| US5658785A (en) | 1994-06-06 | 1997-08-19 | Children's Hospital, Inc. | Adeno-associated virus materials and methods |
| US5856152A (en) | 1994-10-28 | 1999-01-05 | The Trustees Of The University Of Pennsylvania | Hybrid adenovirus-AAV vector and methods of use therefor |
| CA2207927A1 (en) | 1994-12-06 | 1996-06-13 | Targeted Genetics Corporation | Packaging cell lines for generation of high titers of recombinant aav vectors |
| FR2737730B1 (fr) | 1995-08-10 | 1997-09-05 | Pasteur Merieux Serums Vacc | Procede de purification de virus par chromatographie |
| WO1997008298A1 (en) | 1995-08-30 | 1997-03-06 | Genzyme Corporation | Chromatographic purification of adenovirus and aav |
| US6632670B1 (en) | 1995-09-08 | 2003-10-14 | Genzyme Corporation | AAV vectors for gene therapy |
| US5910434A (en) | 1995-12-15 | 1999-06-08 | Systemix, Inc. | Method for obtaining retroviral packaging cell lines producing high transducing efficiency retroviral supernatant |
| JP2001500497A (ja) | 1996-09-06 | 2001-01-16 | トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | 組換えアデノ随伴ウイルスに指図される遺伝子治療の方法 |
| DK1009808T3 (da) | 1997-09-05 | 2013-01-21 | Genzyme Corp | Fremgangsmåder til generering af hjælper-frie præparater af rekombinante aav-vektorer med høj titer |
| US6566118B1 (en) | 1997-09-05 | 2003-05-20 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| US6258595B1 (en) | 1999-03-18 | 2001-07-10 | The Trustees Of The University Of Pennsylvania | Compositions and methods for helper-free production of recombinant adeno-associated viruses |
| US7056502B2 (en) | 2000-04-28 | 2006-06-06 | The Trustees Of The University Of Pennsylvania | Recombinant aav vectors with AAV5 capsids and AAV5 vectors pseudotyped in heterologous capsids |
| DE60332748D1 (de) | 2002-10-02 | 2010-07-08 | Anges Mg Inc | Arzneimittel gegen hörfunktionsstörungen |
| US9233131B2 (en) | 2003-06-30 | 2016-01-12 | The Regents Of The University Of California | Mutant adeno-associated virus virions and methods of use thereof |
| US9441244B2 (en) | 2003-06-30 | 2016-09-13 | The Regents Of The University Of California | Mutant adeno-associated virus virions and methods of use thereof |
| US9434928B2 (en) | 2011-11-23 | 2016-09-06 | Nationwide Children's Hospital, Inc. | Recombinant adeno-associated virus delivery of alpha-sarcoglycan polynucleotides |
| DE102012007232B4 (de) | 2012-04-07 | 2014-03-13 | Susanne Weller | Verfahren zur Herstellung von rotierenden elektrischen Maschinen |
| JP2015092462A (ja) | 2013-09-30 | 2015-05-14 | Tdk株式会社 | 正極及びそれを用いたリチウムイオン二次電池 |
| WO2015141521A1 (ja) | 2014-03-21 | 2015-09-24 | 株式会社日立国際電気 | 基板処理装置、半導体装置の製造方法及び記録媒体 |
| JP6197169B2 (ja) | 2014-09-29 | 2017-09-20 | 東芝メモリ株式会社 | 半導体装置の製造方法 |
| SG10201913266UA (en) | 2015-12-11 | 2020-02-27 | Massachusetts Eye & Ear Infirmary | Materials and methods for delivering nucleic acids to cochlear and vestibular cells |
| US11446398B2 (en) * | 2016-04-11 | 2022-09-20 | Obsidian Therapeutics, Inc. | Regulated biocircuit systems |
| EP3510161A4 (en) * | 2016-08-23 | 2020-04-22 | Akouos, Inc. | COMPOSITIONS AND METHODS FOR TREATING PERSONAL HEARING LOSS IN A PERSON |
| WO2019200016A1 (en) * | 2018-04-10 | 2019-10-17 | President And Fellows Of Harvard College | Aav vectors encoding clarin-1 or gjb2 and uses thereof |
| KR102934700B1 (ko) * | 2019-03-28 | 2026-03-09 | 더 제너럴 하스피탈 코포레이션 | 트랜스진 발현을 위한 조작된 아데노-연관 (aav) 벡터 |
-
2020
- 2020-10-19 AU AU2020366531A patent/AU2020366531A1/en active Pending
- 2020-10-19 WO PCT/US2020/056385 patent/WO2021077115A1/en not_active Ceased
- 2020-10-19 EP EP20804399.2A patent/EP4045092A1/en active Pending
- 2020-10-19 JP JP2022523048A patent/JP7792900B2/ja active Active
- 2020-10-19 CA CA3158286A patent/CA3158286A1/en active Pending
- 2020-10-19 US US17/769,952 patent/US20220378945A1/en active Pending
-
2025
- 2025-07-30 JP JP2025127052A patent/JP2025163105A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022552015A5 (https=) | ||
| Deverman et al. | Gene therapy for neurological disorders: progress and prospects | |
| JP6754361B2 (ja) | 若年型バッテン病のための遺伝子療法 | |
| Luo et al. | Adeno-associated virus-mediated cancer gene therapy: current status | |
| JP2021532812A5 (https=) | ||
| CN102227500B (zh) | 胆色素原脱氨酶基因治疗 | |
| US10494645B2 (en) | Effective delivery of large genes by dual AAV vectors | |
| JP2022505402A5 (https=) | ||
| JP2023515072A5 (https=) | ||
| KR20260009954A (ko) | 합성 간-향성 아데노-연관 바이러스 캡시드 및 그의 용도 | |
| Bankoti et al. | Advances and challenges in adeno-associated viral inner-ear gene therapy for sensorineural hearing loss | |
| US20230416757A1 (en) | Sod1 dual expression vectors and uses thereof | |
| JP2025507338A (ja) | Ａａｖカプシドバリアント及びその使用 | |
| JP2022525302A5 (https=) | ||
| JP2020509786A5 (https=) | ||
| CN120380153A (zh) | 用于中枢神经系统中的基因表达的核酸调控元件以及使用方法 | |
| JP2023500793A5 (https=) | ||
| JP2024539123A5 (https=) | ||
| WO2020210705A1 (en) | Aav-cas13d vectors and uses thereof | |
| US20230340489A1 (en) | Compositions and methods for treating amyotrophic lateral sclerosis (als) with aav-mir-sod1 | |
| JP2021534766A5 (https=) | ||
| JP2025509262A5 (https=) | ||
| JP2024515629A5 (https=) | ||
| WO2020210592A1 (en) | Recombinant aav gene therapy for ngyl1 deficiency | |
| CN116656704B (zh) | 用于治疗法布里病的转基因表达盒 |