JP2022550816A5 - - Google Patents
Info
- Publication number
- JP2022550816A5 JP2022550816A5 JP2022520223A JP2022520223A JP2022550816A5 JP 2022550816 A5 JP2022550816 A5 JP 2022550816A5 JP 2022520223 A JP2022520223 A JP 2022520223A JP 2022520223 A JP2022520223 A JP 2022520223A JP 2022550816 A5 JP2022550816 A5 JP 2022550816A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- item
- antibody according
- seq
- conjugated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025066906A JP7864224B2 (ja) | 2019-10-04 | 2025-04-15 | 抗ｐｄ－ｌ１抗体および抗体－薬物コンジュゲート |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962910988P | 2019-10-04 | 2019-10-04 | |
| US62/910,988 | 2019-10-04 | ||
| PCT/US2020/054037 WO2021067776A2 (en) | 2019-10-04 | 2020-10-02 | Anti-pd-l1 antibodies and antibody-drug conjugates |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025066906A Division JP7864224B2 (ja) | 2019-10-04 | 2025-04-15 | 抗ｐｄ－ｌ１抗体および抗体－薬物コンジュゲート |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022550816A JP2022550816A (ja) | 2022-12-05 |
| JP2022550816A5 true JP2022550816A5 (OSRAM) | 2023-08-07 |
| JP7668791B2 JP7668791B2 (ja) | 2025-04-25 |
Family
ID=72964849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022520223A Active JP7668791B2 (ja) | 2019-10-04 | 2020-10-02 | 抗ｐｄ－ｌ１抗体および抗体－薬物コンジュゲート |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US12421312B2 (OSRAM) |
| EP (1) | EP4038101A2 (OSRAM) |
| JP (1) | JP7668791B2 (OSRAM) |
| KR (1) | KR20220075351A (OSRAM) |
| CN (1) | CN115151564B (OSRAM) |
| AR (1) | AR120147A1 (OSRAM) |
| AU (1) | AU2020358859A1 (OSRAM) |
| BR (1) | BR112022005114A2 (OSRAM) |
| CA (1) | CA3155634A1 (OSRAM) |
| IL (1) | IL291541A (OSRAM) |
| MX (1) | MX2022003517A (OSRAM) |
| TW (1) | TWI883057B (OSRAM) |
| WO (1) | WO2021067776A2 (OSRAM) |
| ZA (1) | ZA202204437B (OSRAM) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112020020466A2 (pt) * | 2018-04-06 | 2021-01-12 | Seattle Genetics, Inc. | Conjugados de peptídeo de camptotecina |
| CA3213636A1 (en) | 2021-03-18 | 2022-09-22 | Seagen Inc. | Selective drug release from internalized conjugates of biologically active compounds |
| WO2022237884A1 (zh) * | 2021-05-13 | 2022-11-17 | 清华大学 | 一种抗体药物偶联物及其制备方法和应用 |
| EP4340877A4 (en) * | 2021-05-21 | 2026-04-29 | Remegen Co Ltd | USE OF AN ANTIBODY-DRUG CONJUGATE IN COMBINATION WITH AN IMMUNE CHECKPOINT INHIBITOR IN THE TREATMENT OF UROTHELIAL CANCER |
| GB2629959A (en) * | 2021-12-29 | 2024-11-13 | Curateq Biologics Private Ltd | C1Q binding assay |
| CN118401564A (zh) * | 2022-01-18 | 2024-07-26 | Fbd生物制品有限公司 | 靶向cd47/pd-l1的蛋白质复合物和其使用方法 |
| EP4523704A1 (en) * | 2022-05-12 | 2025-03-19 | Hainan Simcere Zaiming Pharmaceutical Co., Ltd. | Camptothecin derivative and ligand-drug conjugate |
| AU2023320054A1 (en) * | 2022-08-03 | 2025-02-06 | Regents Of The University Of Minnesota | Immunostimulatory anti-pd-l1-drug conjugates |
| AU2023359114A1 (en) | 2022-10-09 | 2025-04-24 | LaNova Medicines Limited | Compounds, compositions and methods |
| CN121969397A (zh) * | 2023-04-05 | 2026-05-01 | 维硕公司 | 抗体偶联药物及其用途 |
| CN121285392A (zh) | 2023-05-09 | 2026-01-06 | 上海复宏汉霖生物技术股份有限公司 | 一种抗pdl1抗体-药物偶联物及应用 |
| CN119451994A (zh) | 2023-05-31 | 2025-02-14 | Fbd生物制品有限公司 | 靶向cd47/pd-l1的蛋白质复合物和其使用方法 |
| KR20260049221A (ko) * | 2023-07-29 | 2026-04-13 | 상하이 카이진 바이오테크놀로지, 리미티드 | 변형된 e형 다중특이성 항체 |
| WO2025149947A1 (en) | 2024-01-12 | 2025-07-17 | Seagen Inc. | Antibody-drug conjugates |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4714681A (en) | 1981-07-01 | 1987-12-22 | The Board Of Reagents, The University Of Texas System Cancer Center | Quadroma cells and trioma cells and methods for the production of same |
| US4474893A (en) | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
| DE3668186D1 (de) | 1985-04-01 | 1990-02-15 | Celltech Ltd | Transformierte myeloma-zell-linie und dieselbe verwendendes verfahren zur expression eines gens, das ein eukaryontisches polypeptid kodiert. |
| US5981216A (en) | 1985-04-01 | 1999-11-09 | Alusuisse Holdings A.G. | Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US4880935A (en) | 1986-07-11 | 1989-11-14 | Icrf (Patents) Limited | Heterobifunctional linking agents derived from N-succinimido-dithio-alpha methyl-methylene-benzoates |
| EP0307434B2 (en) | 1987-03-18 | 1998-07-29 | Scotgen Biopharmaceuticals, Inc. | Altered antibodies |
| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| FI102355B1 (fi) | 1988-02-11 | 1998-11-30 | Bristol Myers Squibb Co | Menetelmä yhdistävän välikappaleen omaavien antrasykliini-immunokonjugaattien valmistamiseksi |
| US5879936A (en) | 1988-04-18 | 1999-03-09 | Aluguisse Holding A.G. | Recombinant DNA methods, vectors and host cells |
| GB8809129D0 (en) | 1988-04-18 | 1988-05-18 | Celltech Ltd | Recombinant dna methods vectors and host cells |
| ATE120454T1 (de) | 1988-06-14 | 1995-04-15 | Cetus Oncology Corp | Kupplungsmittel und sterisch gehinderte, mit disulfid gebundene konjugate daraus. |
| US4925648A (en) | 1988-07-29 | 1990-05-15 | Immunomedics, Inc. | Detection and treatment of infectious and inflammatory lesions |
| US5601819A (en) | 1988-08-11 | 1997-02-11 | The General Hospital Corporation | Bispecific antibodies for selective immune regulation and for selective immune cell binding |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| EP0479909B1 (en) | 1989-06-29 | 1996-10-30 | Medarex, Inc. | Bispecific reagents for aids therapy |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| US5891693A (en) | 1990-01-25 | 1999-04-06 | Alusuisse Holdings A.G. | Recombinant DNA methods vectors and host cells |
| JP3583420B2 (ja) | 1990-10-05 | 2004-11-04 | メダレツクス・インコーポレーテツド | 二特異的試薬を用いた標的免疫化 |
| AU8727291A (en) | 1990-10-29 | 1992-06-11 | Cetus Oncology Corporation | Bispecific antibodies, method of production, and uses thereof |
| IE921342A1 (en) | 1991-04-26 | 1992-11-04 | Surface Active Ltd | Novel antibodies, and methods for their use |
| ATE255131T1 (de) | 1991-06-14 | 2003-12-15 | Genentech Inc | Humanisierter heregulin antikörper |
| US5622929A (en) | 1992-01-23 | 1997-04-22 | Bristol-Myers Squibb Company | Thioether conjugates |
| GB9203459D0 (en) | 1992-02-19 | 1992-04-08 | Scotgen Ltd | Antibodies with germ-line variable regions |
| WO1993017715A1 (en) | 1992-03-05 | 1993-09-16 | Board Of Regents, The University Of Texas System | Diagnostic and/or therapeutic agents, targeted to neovascular endothelial cells |
| US6214345B1 (en) | 1993-05-14 | 2001-04-10 | Bristol-Myers Squibb Co. | Lysosomal enzyme-cleavable antitumor drug conjugates |
| EP0871490B1 (en) | 1995-12-22 | 2003-03-19 | Bristol-Myers Squibb Company | Branched hydrazone linkers |
| US5834597A (en) | 1996-05-20 | 1998-11-10 | Protein Design Labs, Inc. | Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same |
| US6130237A (en) | 1996-09-12 | 2000-10-10 | Cancer Research Campaign Technology Limited | Condensed N-aclyindoles as antitumor agents |
| DE60045319D1 (de) | 1999-02-05 | 2011-01-13 | Samsung Electronics Co Ltd | Verfahren und Vorrichtung zum Wiederauffinden von Texturbildern |
| MXPA05000511A (es) | 2001-07-12 | 2005-09-30 | Jefferson Foote | Anticuepros super humanizados. |
| ES2544527T3 (es) | 2002-07-31 | 2015-09-01 | Seattle Genetics, Inc. | Conjugados de fármacos y su uso para tratar el cáncer, una enfermedad autoinmune o una enfermedad infecciosa |
| EP3434275A1 (en) | 2003-11-06 | 2019-01-30 | Seattle Genetics, Inc. | Assay for cancer cells based on the use of auristatin conjugates with antibodies |
| GEP20115195B (en) | 2004-07-30 | 2011-04-11 | Rinat Neuroscience Corp | Antibodies directed against amyloid-beta peptide and use thereof |
| CA2612241C (en) * | 2005-07-01 | 2018-11-06 | Medarex, Inc. | Human monoclonal antibodies to programmed death ligand 1 (pd-l1) |
| JP5171621B2 (ja) | 2005-07-07 | 2013-03-27 | シアトル ジェネティックス， インコーポレイテッド | フェニルアラニン側鎖修飾をｃ末端に有するモノメチルバリン化合物 |
| WO2007008848A2 (en) | 2005-07-07 | 2007-01-18 | Seattle Genetics, Inc. | Monomethylvaline compounds having phenylalanine carboxy modifications at the c-terminus |
| DK2099823T4 (da) | 2006-12-01 | 2022-05-09 | Seagen Inc | Målbindingsmiddelvarianter og anvendelser deraf |
| WO2009052431A2 (en) | 2007-10-19 | 2009-04-23 | Seattle Genetics, Inc. | Cd19 binding agents and uses thereof |
| EA035374B1 (ru) | 2015-03-18 | 2020-06-03 | Сиэтл Дженетикс, Инк. | Антитела против cd48 и их конъюгаты |
| US11549099B2 (en) * | 2016-03-23 | 2023-01-10 | Novartis Ag | Cell secreted minibodies and uses thereof |
| KR102367074B1 (ko) | 2016-03-29 | 2022-02-25 | 주식회사 에스티큐브 | 글리코실화된 pd-l1에 특이적인 이중 기능 항체 및 이의 사용 방법 |
| US11135307B2 (en) * | 2016-11-23 | 2021-10-05 | Mersana Therapeutics, Inc. | Peptide-containing linkers for antibody-drug conjugates |
| EP3610042A1 (en) * | 2017-04-14 | 2020-02-19 | H. Hoffnabb-La Roche Ag | Diagnostic and therapeutic methods for cancer |
| WO2019148089A1 (en) * | 2018-01-26 | 2019-08-01 | Orionis Biosciences Inc. | Xcr1 binding agents and uses thereof |
| BR112020020466A2 (pt) * | 2018-04-06 | 2021-01-12 | Seattle Genetics, Inc. | Conjugados de peptídeo de camptotecina |
-
2020
- 2020-10-02 KR KR1020227012974A patent/KR20220075351A/ko active Pending
- 2020-10-02 CA CA3155634A patent/CA3155634A1/en active Pending
- 2020-10-02 EP EP20793914.1A patent/EP4038101A2/en active Pending
- 2020-10-02 US US17/061,998 patent/US12421312B2/en active Active
- 2020-10-02 BR BR112022005114A patent/BR112022005114A2/pt unknown
- 2020-10-02 MX MX2022003517A patent/MX2022003517A/es unknown
- 2020-10-02 CN CN202080082113.4A patent/CN115151564B/zh active Active
- 2020-10-02 AR ARP200102743A patent/AR120147A1/es unknown
- 2020-10-02 WO PCT/US2020/054037 patent/WO2021067776A2/en not_active Ceased
- 2020-10-02 JP JP2022520223A patent/JP7668791B2/ja active Active
- 2020-10-02 AU AU2020358859A patent/AU2020358859A1/en active Pending
- 2020-10-05 TW TW109134497A patent/TWI883057B/zh active
-
2022
- 2022-03-21 IL IL291541A patent/IL291541A/en unknown
- 2022-04-20 ZA ZA2022/04437A patent/ZA202204437B/en unknown
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