JP2022549351A5 - - Google Patents

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Publication number
JP2022549351A5
JP2022549351A5 JP2022519303A JP2022519303A JP2022549351A5 JP 2022549351 A5 JP2022549351 A5 JP 2022549351A5 JP 2022519303 A JP2022519303 A JP 2022519303A JP 2022519303 A JP2022519303 A JP 2022519303A JP 2022549351 A5 JP2022549351 A5 JP 2022549351A5
Authority
JP
Japan
Prior art keywords
polypeptide
heterodimer protein
protein according
polynucleotide encoding
heavy chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022519303A
Other languages
English (en)
Japanese (ja)
Other versions
JP7842011B2 (ja
JP2022549351A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/053114 external-priority patent/WO2021062382A1/en
Publication of JP2022549351A publication Critical patent/JP2022549351A/ja
Publication of JP2022549351A5 publication Critical patent/JP2022549351A5/ja
Application granted granted Critical
Publication of JP7842011B2 publication Critical patent/JP7842011B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022519303A 2019-09-27 2020-09-28 ヘテロ二量体タンパク質 Active JP7842011B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962906918P 2019-09-27 2019-09-27
US62/906,918 2019-09-27
PCT/US2020/053114 WO2021062382A1 (en) 2019-09-27 2020-09-28 Heterodimeric proteins

Publications (3)

Publication Number Publication Date
JP2022549351A JP2022549351A (ja) 2022-11-24
JP2022549351A5 true JP2022549351A5 (enExample) 2023-10-06
JP7842011B2 JP7842011B2 (ja) 2026-04-07

Family

ID=75166489

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022519303A Active JP7842011B2 (ja) 2019-09-27 2020-09-28 ヘテロ二量体タンパク質

Country Status (10)

Country Link
US (2) US20210130495A1 (enExample)
EP (1) EP4034570A4 (enExample)
JP (1) JP7842011B2 (enExample)
KR (1) KR20220069935A (enExample)
CN (1) CN114787186B (enExample)
AU (1) AU2020355253A1 (enExample)
BR (1) BR112022004789A2 (enExample)
IL (1) IL291618A (enExample)
MX (1) MX2022003149A (enExample)
WO (1) WO2021062382A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190016802A1 (en) 2017-07-14 2019-01-17 Immatics Biotechnologies Gmbh Dual specificity polypeptide molecule
WO2022233956A1 (en) 2021-05-05 2022-11-10 Immatics Biotechnologies Gmbh Antigen binding proteins specifically binding prame

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0979281B1 (en) * 1997-05-02 2005-07-20 Genentech, Inc. A method for making multispecific antibodies having heteromultimeric and common components
US8093357B2 (en) * 2002-03-01 2012-01-10 Xencor, Inc. Optimized Fc variants and methods for their generation
WO2005047327A2 (en) * 2003-11-12 2005-05-26 Biogen Idec Ma Inc. NEONATAL Fc RECEPTOR (FcRn)-BINDING POLYPEPTIDE VARIANTS, DIMERIC Fc BINDING PROTEINS AND METHODS RELATED THERETO
TW201302793A (zh) * 2010-09-03 2013-01-16 Glaxo Group Ltd 新穎之抗原結合蛋白
US10689447B2 (en) 2011-02-04 2020-06-23 Genentech, Inc. Fc variants and methods for their production
WO2013033008A2 (en) * 2011-08-26 2013-03-07 Merrimack Pharmaceuticals, Inc. Tandem fc bispecific antibodies
US9574010B2 (en) * 2011-11-04 2017-02-21 Zymeworks Inc. Stable heterodimeric antibody design with mutations in the Fc domain
CN105102618B (zh) * 2012-12-27 2018-04-17 中外制药株式会社 异源二聚化多肽
MX2019004327A (es) * 2016-10-14 2019-10-14 Xencor Inc Proteinas de fusion heterodimericas biespecificas que contienen proteinas de fusion fc il-15/il-15ra y fragmentos de anticuerpo pd-1.
KR20200014379A (ko) * 2017-06-05 2020-02-10 얀센 바이오테크 인코포레이티드 비대칭 ch2-ch3 영역 돌연변이를 갖는 조작된 다중특이성 항체 및 다른 다량체 단백질
CN110028584B (zh) 2018-01-12 2021-04-06 北京科昕生物科技有限公司 针对egfr蛋白和met蛋白的双特异性抗体
KR20210080460A (ko) * 2018-10-23 2021-06-30 드래곤플라이 쎄라퓨틱스, 인크. 이종이량체성 Fc-융합된 단백질

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