JP2022549303A - 免疫細胞を拡大増殖するためのｃｂｌ阻害剤および組成物 - Google Patents

免疫細胞を拡大増殖するためのｃｂｌ阻害剤および組成物 Download PDF

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JP2022549303A
JP2022549303A JP2022518710A JP2022518710A JP2022549303A JP 2022549303 A JP2022549303 A JP 2022549303A JP 2022518710 A JP2022518710 A JP 2022518710A JP 2022518710 A JP2022518710 A JP 2022518710A JP 2022549303 A JP2022549303 A JP 2022549303A
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cells
days
cbl
expansion
cell
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JPWO2021061870A5 (https=
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ティー． サンズ，アーサー
ゴスリング，ジェニファ
アン ウィーラン，サラ
ロッツェ，マイケル
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ニューリックス セラピューティクス，インコーポレイテッド
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JP2022518710A 2019-09-24 2020-09-23 免疫細胞を拡大増殖するためのｃｂｌ阻害剤および組成物 Pending JP2022549303A (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201962905124P 2019-09-24 2019-09-24
US62/905,124 2019-09-24
US201962954323P 2019-12-27 2019-12-27
US62/954,323 2019-12-27
US202062961596P 2020-01-15 2020-01-15
US62/961,596 2020-01-15
US202062978254P 2020-02-18 2020-02-18
US62/978,254 2020-02-18
US202063032462P 2020-05-29 2020-05-29
US63/032,462 2020-05-29
PCT/US2020/052335 WO2021061870A1 (en) 2019-09-24 2020-09-23 Cbl inhibitors and compositions for expansion of immune cells

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JP2022549303A true JP2022549303A (ja) 2022-11-24
JPWO2021061870A5 JPWO2021061870A5 (https=) 2023-10-03
JP2022549303A5 JP2022549303A5 (https=) 2023-10-03

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JP2022518710A Pending JP2022549303A (ja) 2019-09-24 2020-09-23 免疫細胞を拡大増殖するためのｃｂｌ阻害剤および組成物
JP2022518768A Pending JP2022549007A (ja) 2019-09-24 2020-09-23 養子細胞療法に使用するためのｃｂｌ阻害剤および組成物

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US (2) US12121540B2 (https=)
EP (2) EP4034141A1 (https=)
JP (2) JP2022549303A (https=)
KR (2) KR20220068227A (https=)
CN (2) CN114786687A (https=)
AU (2) AU2020352609A1 (https=)
CA (2) CA3152281A1 (https=)
IL (2) IL291579A (https=)
WO (2) WO2021061870A1 (https=)

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WO2019148005A1 (en) * 2018-01-26 2019-08-01 Nurix Therapeutics, Inc. Inhibitors of cbl-b and methods of use thereof
JP7600123B2 (ja) 2018-10-15 2024-12-16 ニューリックス セラピューティクス，インコーポレイテッド ユビキチンプロテオソーム経路を介してｂｔｋを分解するための二官能性化合物
WO2020167518A1 (en) 2019-02-13 2020-08-20 Nurix Therapeutics, Inc. Bifunctional compounds for degrading btk via ubiquitin proteosome pathway
EP3953346A1 (en) 2019-04-09 2022-02-16 Nurix Therapeutics, Inc. 3-substituted piperidine compounds for cbl-b inhibition, and use of a cbl-b inhibitor in combination with a cancer vaccine and/or oncolytic virus
EP3969447A1 (en) 2019-05-17 2022-03-23 Nurix Therapeutics, Inc. Cyano cyclobutyl compounds for cbl-b inhibition and uses thereof
MX2021015675A (es) 2019-06-26 2022-02-03 Nurix Therapeutics Inc Compuestos de bencil-triazol sustituidos para la inhibicion de cbl-b y otros usos de los mismos.
EP4034141A1 (en) 2019-09-24 2022-08-03 Nurix Therapeutics, Inc. Cbl inhibitors and compositions for expansion of immune cells
US11820781B2 (en) 2019-12-04 2023-11-21 Nurix Therapeutics, Inc. Bifunctional compounds for degrading BTK via ubiquitin proteosome pathway
US12365871B2 (en) 2020-04-28 2025-07-22 Lyell Immunopharma, Inc. Methods for culturing cells
US12016860B2 (en) 2021-04-08 2024-06-25 Nurix Therapeutics, Inc. Combination therapies with Cbl-b inhibitor compounds
AU2022379494A1 (en) 2021-10-26 2024-05-30 Nurix Therapeutics, Inc. Piperidinylpyrazine-carboxamide compounds for treating and preventing cancer and for degrading btk
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