JP2022549156A5 - - Google Patents
Info
- Publication number
- JP2022549156A5 JP2022549156A5 JP2022517410A JP2022517410A JP2022549156A5 JP 2022549156 A5 JP2022549156 A5 JP 2022549156A5 JP 2022517410 A JP2022517410 A JP 2022517410A JP 2022517410 A JP2022517410 A JP 2022517410A JP 2022549156 A5 JP2022549156 A5 JP 2022549156A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- seq
- dkk1
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962902857P | 2019-09-19 | 2019-09-19 | |
| US62/902,857 | 2019-09-19 | ||
| PCT/US2020/051550 WO2021055789A1 (en) | 2019-09-19 | 2020-09-18 | Use of dkk-1 inhibitors for treating cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022549156A JP2022549156A (ja) | 2022-11-24 |
| JP2022549156A5 true JP2022549156A5 (https=) | 2023-09-11 |
Family
ID=72670867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022517410A Pending JP2022549156A (ja) | 2019-09-19 | 2020-09-18 | 癌を治療するためのdkk-1阻害剤の使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220381786A1 (https=) |
| EP (1) | EP4031175A1 (https=) |
| JP (1) | JP2022549156A (https=) |
| KR (1) | KR102883931B1 (https=) |
| CN (1) | CN114423459A (https=) |
| AU (1) | AU2020348457A1 (https=) |
| BR (1) | BR112022004851A2 (https=) |
| CA (1) | CA3151228A1 (https=) |
| IL (1) | IL291424A (https=) |
| MX (1) | MX2022003396A (https=) |
| WO (1) | WO2021055789A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3041325A1 (en) | 2016-10-26 | 2018-05-03 | Leap Therapeutics, Inc. | Use of beta-catenin as a biomarker for treating cancers using anti-dkk-1 antibody |
| WO2023039249A1 (en) * | 2021-09-10 | 2023-03-16 | Leap Therapeutics, Inc. | Combination therapy |
| IL318268A (en) * | 2022-07-12 | 2025-03-01 | Leap Therapeutics Inc | Combined treatment |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1735350A (en) | 1921-07-02 | 1929-11-12 | United Shoe Machinery Corp | Machine for securing together two or more pieces of sheet material |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4318980A (en) | 1978-04-10 | 1982-03-09 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing a cycling reactant as label |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5411947A (en) | 1989-06-28 | 1995-05-02 | Vestar, Inc. | Method of converting a drug to an orally available form by covalently bonding a lipid to the drug |
| US5475120A (en) | 1990-11-02 | 1995-12-12 | University Of Florida | Method for the isolation and purification of taxol and its natural analogues |
| US5194635A (en) | 1991-03-18 | 1993-03-16 | Virginia Tech Intellectual Properties, Inc. | Rearranged taxol compounds and method of using in testing of in vivo activity |
| US5488116A (en) | 1992-03-30 | 1996-01-30 | Sloan-Kettering Institute For Cancer Research | Total synthesis of taxol and analogues thereof |
| US5416225A (en) | 1992-03-30 | 1995-05-16 | Sloan-Kettering Institute For Cancer Research | Total synthesis of taxol |
| US5440056A (en) | 1992-04-17 | 1995-08-08 | Abbott Laboratories | 9-deoxotaxane compounds |
| CA2130578A1 (en) | 1992-04-17 | 1993-10-28 | Geewananda P. Gunawardana | Taxol derivatives |
| US5461169A (en) | 1992-06-23 | 1995-10-24 | The Scripps Research Institute | Total synthesis of taxol and taxol analogs |
| US5440057A (en) | 1993-08-20 | 1995-08-08 | The Scripps Research Institute | Access to taxol analogs |
| WO1994005282A1 (en) | 1992-09-04 | 1994-03-17 | The Scripps Research Institute | Water soluble taxol derivatives |
| US5478854A (en) | 1992-10-01 | 1995-12-26 | Bristol-Myers Squibb Company | Deoxy taxols |
| US5411984A (en) | 1992-10-16 | 1995-05-02 | Virginia Tech Intellectual Properties, Inc. | Water soluble analogs and prodrugs of taxol |
| WO1994013827A1 (en) | 1992-12-07 | 1994-06-23 | Michigan State University | PROCESS FOR THE ISOLATION AND PURIFICATION OF TAXOL AND TAXANES FROM TAXUS spp |
| US5468769A (en) | 1993-07-15 | 1995-11-21 | Abbott Laboratories | Paclitaxel derivatives |
| FR2707642B1 (fr) | 1993-07-16 | 1995-10-13 | Electricite De France | Dérivés de polyéthers et d'hétérocycles pentacycliques, leurs polymères et leurs applications, notamment à la complexation d'ions métalliques. |
| US5405972A (en) | 1993-07-20 | 1995-04-11 | Florida State University | Synthetic process for the preparation of taxol and other tricyclic and tetracyclic taxanes |
| US5565478A (en) | 1994-03-14 | 1996-10-15 | The United States Of America As Represented By The Department Of Health & Human Services | Combination therapy using signal transduction inhibitors with paclitaxel and other taxane analogs |
| US5508447A (en) | 1994-05-24 | 1996-04-16 | Board Of Regents, The University Of Texas System | Short synthetic route to taxol and taxol derivatives |
| US5489589A (en) | 1994-12-07 | 1996-02-06 | Bristol-Myers Squibb Company | Amino acid derivatives of paclitaxel |
| US7446181B2 (en) | 1998-01-15 | 2008-11-04 | Millennium Pharmaceuticals, Inc. | Antibodies that bind human Dickkopf-1 proteins |
| WO2009028158A1 (en) * | 2007-08-24 | 2009-03-05 | Oncotherapy Science, Inc. | Dkk1 oncogene as therapeutic target for cancer and a diagnosing marker |
| AR075989A1 (es) | 2009-04-10 | 2011-05-11 | Lilly Co Eli | Anticuerpo dkk -1 (dickkopf-1) humano disenado por ingenieria |
| CA3041325A1 (en) * | 2016-10-26 | 2018-05-03 | Leap Therapeutics, Inc. | Use of beta-catenin as a biomarker for treating cancers using anti-dkk-1 antibody |
| EP4061419A1 (en) * | 2019-11-22 | 2022-09-28 | Leap Therapeutics, Inc. | Methods of treating cancer using dkk-1-inhibitors |
-
2020
- 2020-09-18 CA CA3151228A patent/CA3151228A1/en active Pending
- 2020-09-18 JP JP2022517410A patent/JP2022549156A/ja active Pending
- 2020-09-18 KR KR1020227012391A patent/KR102883931B1/ko active Active
- 2020-09-18 US US17/761,946 patent/US20220381786A1/en active Pending
- 2020-09-18 MX MX2022003396A patent/MX2022003396A/es unknown
- 2020-09-18 AU AU2020348457A patent/AU2020348457A1/en active Pending
- 2020-09-18 WO PCT/US2020/051550 patent/WO2021055789A1/en not_active Ceased
- 2020-09-18 BR BR112022004851A patent/BR112022004851A2/pt unknown
- 2020-09-18 EP EP20781734.7A patent/EP4031175A1/en active Pending
- 2020-09-18 CN CN202080065948.9A patent/CN114423459A/zh active Pending
-
2022
- 2022-03-16 IL IL291424A patent/IL291424A/en unknown
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