JP2022546454A - がん処置のためのｈｅｒ２、ｎｋｇ２ｄおよびｃｄ１６に結合する多重特異性結合タンパク質の医薬製剤および投薬量レジメン - Google Patents

がん処置のためのｈｅｒ２、ｎｋｇ２ｄおよびｃｄ１６に結合する多重特異性結合タンパク質の医薬製剤および投薬量レジメン Download PDF

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JP2022546454A
JP2022546454A JP2022513347A JP2022513347A JP2022546454A JP 2022546454 A JP2022546454 A JP 2022546454A JP 2022513347 A JP2022513347 A JP 2022513347A JP 2022513347 A JP2022513347 A JP 2022513347A JP 2022546454 A JP2022546454 A JP 2022546454A
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pharmaceutical formulation
chain variable
amino acid
variable domain
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グレゴリー ピー． チャン，
アン エフ． チュン，
ジャン－マリー シレロット，
アシャ グリンバーグ，
ウィリアム ヘイニー，
クリストファー ライアン モーガン，
マイケル シー． ナイル，
ニコライ ワグトマン，
ロニー ウェイ，
スティーブン オニール，
ダニエル ファロン，
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ドラゴンフライ セラピューティクス， インコーポレイテッド
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Publication of JP2022546454A publication Critical patent/JP2022546454A/ja
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JP2022513347A 2019-08-30 2020-08-28 がん処置のためのｈｅｒ２、ｎｋｇ２ｄおよびｃｄ１６に結合する多重特異性結合タンパク質の医薬製剤および投薬量レジメン Pending JP2022546454A (ja)

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JP2025010364A JP2025061790A (ja) 2019-08-30 2025-01-24 がん処置のためのｈｅｒ２、ｎｋｇ２ｄおよびｃｄ１６に結合する多重特異性結合タンパク質の医薬製剤および投薬量レジメン

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US201962894047P 2019-08-30 2019-08-30
US62/894,047 2019-08-30
US201962895320P 2019-09-03 2019-09-03
US62/895,320 2019-09-03
US201962916935P 2019-10-18 2019-10-18
US62/916,935 2019-10-18
PCT/US2020/048500 WO2021041878A1 (en) 2019-08-30 2020-08-28 Pharmaceutical formulations and dosage regimens for multi-specific binding proteins that bind her2, nkg2d, and cd16 for cancer treatment

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JP2025010364A Pending JP2025061790A (ja) 2019-08-30 2025-01-24 がん処置のためのｈｅｒ２、ｎｋｇ２ｄおよびｃｄ１６に結合する多重特異性結合タンパク質の医薬製剤および投薬量レジメン

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US (1) US20220195065A1 (https=)
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KR (1) KR20220054649A (https=)
CN (2) CN114630842A (https=)
AU (1) AU2020337999A1 (https=)
BR (1) BR112022003707A2 (https=)
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Families Citing this family (12)

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AU2018219887B2 (en) 2017-02-08 2024-08-15 Dragonfly Therapeutics, LLC Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
CN110944661A (zh) 2017-02-20 2020-03-31 蜻蜓疗法股份有限公司 结合her2、nkg2d和cd16的蛋白质
BR112020015994A2 (pt) 2018-02-08 2020-12-15 Dragonfly Therapeutics, Inc. Terapia de combinação do câncer que envolve proteínas de ligação multiespecíficas que ativam células natural killer
CA3237846A1 (en) 2018-02-08 2019-08-15 Dragonfly Therapeutics, Inc. Antibody variable domains targeting the nkg2d receptor
WO2019164930A1 (en) 2018-02-20 2019-08-29 Dragonfly Therapeutics, Inc. Multi-specific binding proteins that bind cd33, nkg2d, and cd16, and methods of use
KR102835308B1 (ko) 2018-08-08 2025-07-21 드래곤플라이 쎄라퓨틱스, 인크. Nkg2d, cd16 및 종양 관련 항원에 결합하는 단백질
EA202091888A1 (ru) 2018-08-08 2020-10-23 Драгонфлай Терапьютикс, Инк. Вариабельные домены антител, нацеленные на рецептор nkg2d
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