JP2022544536A5 - - Google Patents
Info
- Publication number
- JP2022544536A5 JP2022544536A5 JP2022509051A JP2022509051A JP2022544536A5 JP 2022544536 A5 JP2022544536 A5 JP 2022544536A5 JP 2022509051 A JP2022509051 A JP 2022509051A JP 2022509051 A JP2022509051 A JP 2022509051A JP 2022544536 A5 JP2022544536 A5 JP 2022544536A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- heteroaralkyl
- aralkyl
- heteroaryl
- substituents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962887732P | 2019-08-16 | 2019-08-16 | |
| US62/887,732 | 2019-08-16 | ||
| PCT/US2020/046269 WO2021034627A1 (en) | 2019-08-16 | 2020-08-14 | Small molecule stimulators of the core particle of the proteasome |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022544536A JP2022544536A (ja) | 2022-10-19 |
| JP2022544536A5 true JP2022544536A5 (enExample) | 2023-06-15 |
| JP7583027B2 JP7583027B2 (ja) | 2024-11-13 |
Family
ID=74659522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022509051A Active JP7583027B2 (ja) | 2019-08-16 | 2020-08-14 | プロテアソームのコア粒子の低分子刺激物質 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220267280A1 (enExample) |
| EP (1) | EP4013405A4 (enExample) |
| JP (1) | JP7583027B2 (enExample) |
| CN (1) | CN114222573A (enExample) |
| WO (1) | WO2021034627A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113620881A (zh) * | 2021-08-12 | 2021-11-09 | 浙江禾本科技股份有限公司 | 一种1-[2-(2,4-二氯苯基)-2羟基乙基]-1h咪唑的合成方法 |
| EP4147723A1 (en) | 2021-09-09 | 2023-03-15 | Booster Therapeutics GmbH | Bifunctional molecules as proteasome stimulators for improved targeted protein degradation, and their uses as targeted boosting degraders (tarbods) |
| EP4398941A1 (en) | 2021-09-09 | 2024-07-17 | Booster Therapeutics GmbH | Bifunctional molecules as proteasome stimulators for improved targeted protein degradation, and their uses as targeted boosting degraders (tarbods) |
| WO2025219559A1 (en) | 2024-04-18 | 2025-10-23 | Booster Therapeutics Gmbh | Pyrrolidine compounds as proteasome stimulators |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU557755A3 (ru) * | 1968-08-19 | 1977-05-05 | Янссен Фармасьютика Н.В. (Фирма) | Способ получени производных имидазола |
| US3991202A (en) * | 1974-01-31 | 1976-11-09 | Janssen Pharmaceutica N.V. | Imidazolium salts |
| US5633274A (en) * | 1993-02-18 | 1997-05-27 | President And Fellows Of Harvard College | Cancer treatments |
| NZ328607A (en) * | 1996-09-09 | 1999-08-30 | Hoffmann La Roche | Heterocyclically substituted n-benzyl-azolium derivatives and fungicidal compositions |
| EP0829478A3 (en) * | 1996-09-09 | 1998-03-25 | F. Hoffmann-La Roche Ag | N-Benzylimidazolium and N-benzyltriazolium derivatives, their preparation and their use as antifungal and antimycotic agents |
| WO2004022546A1 (ja) * | 2002-09-04 | 2004-03-18 | Keimei Oh | ジャスモン酸の生合成を阻害する物質 |
| EP1896406A2 (en) * | 2005-06-14 | 2008-03-12 | Shering Corporation | The preparation and use of compounds as protease inhibitors |
| BRPI0904249B1 (pt) | 2009-08-28 | 2018-03-06 | Biolab Sanus Farmacêutica Ltda. | Compostos éteres aralquil benzílicos, processo de preparação dos mesmos, uso dos referidos compostos, composição farmacêutica |
| CA2990686A1 (en) * | 2015-07-16 | 2017-01-19 | Amari Biopharma, Inc. | Methods of preventing toxicity of platinum drugs comprising administering an oct monitor |
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2020
- 2020-08-14 WO PCT/US2020/046269 patent/WO2021034627A1/en not_active Ceased
- 2020-08-14 US US17/627,527 patent/US20220267280A1/en active Pending
- 2020-08-14 EP EP20855334.7A patent/EP4013405A4/en not_active Withdrawn
- 2020-08-14 JP JP2022509051A patent/JP7583027B2/ja active Active
- 2020-08-14 CN CN202080057165.6A patent/CN114222573A/zh active Pending