JP2022543203A5 - - Google Patents
Info
- Publication number
- JP2022543203A5 JP2022543203A5 JP2022505198A JP2022505198A JP2022543203A5 JP 2022543203 A5 JP2022543203 A5 JP 2022543203A5 JP 2022505198 A JP2022505198 A JP 2022505198A JP 2022505198 A JP2022505198 A JP 2022505198A JP 2022543203 A5 JP2022543203 A5 JP 2022543203A5
- Authority
- JP
- Japan
- Prior art keywords
- difluoromethoxy
- phenyl
- ethyl
- hydroxy
- trifluoromethoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025112976A JP2025160211A (ja) | 2019-08-02 | 2025-07-03 | Ｋｖ７カリウムチャネル開口薬としてのアルコール誘導体 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19189750.3 | 2019-08-02 | ||
| EP19189750 | 2019-08-02 | ||
| CN201910734123 | 2019-08-09 | ||
| CN201910734123.0 | 2019-08-09 | ||
| EP19191887 | 2019-08-15 | ||
| EP19191887.9 | 2019-08-15 | ||
| PCT/EP2020/071520 WO2021023617A1 (en) | 2019-08-02 | 2020-07-30 | Alcohol derivatives as kv7 potassium channel openers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025112976A Division JP2025160211A (ja) | 2019-08-02 | 2025-07-03 | Ｋｖ７カリウムチャネル開口薬としてのアルコール誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022543203A JP2022543203A (ja) | 2022-10-11 |
| JP2022543203A5 true JP2022543203A5 (https=) | 2023-08-04 |
| JP7720829B2 JP7720829B2 (ja) | 2025-08-08 |
Family
ID=71894829
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022505198A Active JP7720829B2 (ja) | 2019-08-02 | 2020-07-30 | Ｋｖ７カリウムチャネル開口薬としてのアルコール誘導体 |
| JP2025112976A Pending JP2025160211A (ja) | 2019-08-02 | 2025-07-03 | Ｋｖ７カリウムチャネル開口薬としてのアルコール誘導体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025112976A Pending JP2025160211A (ja) | 2019-08-02 | 2025-07-03 | Ｋｖ７カリウムチャネル開口薬としてのアルコール誘導体 |
Country Status (26)
| Country | Link |
|---|---|
| EP (2) | EP4007634B1 (https=) |
| JP (2) | JP7720829B2 (https=) |
| CN (1) | CN114206830B (https=) |
| AU (1) | AU2020325517B2 (https=) |
| BR (1) | BR112021006324A2 (https=) |
| CA (1) | CA3148719A1 (https=) |
| CL (1) | CL2022000221A1 (https=) |
| CO (1) | CO2022000080A2 (https=) |
| CR (1) | CR20220028A (https=) |
| DO (1) | DOP2022000026A (https=) |
| EC (1) | ECSP22008993A (https=) |
| ES (1) | ES2989376T3 (https=) |
| GE (2) | GEAP202415862A (https=) |
| HR (1) | HRP20241444T1 (https=) |
| HU (1) | HUE069310T2 (https=) |
| IL (1) | IL290193B2 (https=) |
| JO (1) | JOP20220017A1 (https=) |
| MA (1) | MA56708B1 (https=) |
| MX (1) | MX2022001063A (https=) |
| PE (1) | PE20220345A1 (https=) |
| PH (1) | PH12022550192A1 (https=) |
| PL (1) | PL4007634T3 (https=) |
| RS (1) | RS66130B1 (https=) |
| SM (1) | SMT202400445T1 (https=) |
| WO (1) | WO2021023617A1 (https=) |
| ZA (1) | ZA202109598B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS66130B1 (sr) * | 2019-08-02 | 2024-11-29 | H Lundbeck As | Derivati alkohola kao otvarači kv7 kalijumovih kanala |
| IL325387A (en) * | 2023-06-27 | 2026-02-01 | Saniona As | KV7 modulators |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001092526A1 (en) | 2000-05-26 | 2001-12-06 | Bristol-Myers Squibb Company | Human kcnq5 potassium channel, methods and compositions thereof |
| WO2001096540A2 (en) | 2000-06-11 | 2001-12-20 | Dupont Pharmaceuticals Company | Hepatitis c protease exosite for inhibitor design |
| US7091202B2 (en) * | 2004-09-15 | 2006-08-15 | Bristol-Myers Squibb Company | 4-arylspirocycloalkyl-2-aminopyrimidine carboxamide KCNQ potassium channel modulators |
| TWI453013B (zh) | 2006-02-07 | 2014-09-21 | Lundbeck & Co As H | N-(2,4-二甲基-6-嗎啉-4-基-吡啶-3-基〉3,3-二甲基-丁醯胺之用途以及包含該化合物之醫藥品 |
| WO2007104717A1 (en) * | 2006-03-15 | 2007-09-20 | Neurosearch A/S | Quinazolinones and their use as potassium channels activators |
| AR070513A1 (es) | 2007-08-01 | 2010-04-14 | Lundbeck & Co As H | Uso de abridores de canales de potasio kcnq para reducir los sintomas o tratar desordenes o afecciones en las cuales se encuentra anulado el sis-tema dopaminergico como por ejemplo esquizofrenia y trastorno depresivo mayor |
| TW201024286A (en) * | 2008-11-27 | 2010-07-01 | Neurosearch As | Novel compounds |
| HK1216095A1 (zh) * | 2012-12-10 | 2016-10-14 | H. Lundbeck A/S | 烟碱乙酰胆碱受体的新的正向别构调节剂 |
| WO2014145852A2 (en) * | 2013-03-15 | 2014-09-18 | Knopp Biosciences Llc | Imidazo(4,5-b) pyridin-2-yl amides as kv7 channel activators |
| SMT202300362T1 (it) * | 2014-09-12 | 2023-11-13 | Biohaven Therapeutics Ltd | Benzoimidazol-1,2-il-ammidi come attivatori di canale kv7 |
| JP2017095366A (ja) | 2015-11-18 | 2017-06-01 | 持田製薬株式会社 | 新規ビアリールアミド誘導体 |
| CN105663136A (zh) * | 2016-01-15 | 2016-06-15 | 河北中医学院 | 法舒地尔作为制备选择性Kv7离子通道激活剂药物的应用 |
| EP4241843B1 (en) * | 2018-02-20 | 2025-05-21 | H. Lundbeck A/S | Alcohol derivatives as kv7 potassium channel openers |
| RS66130B1 (sr) * | 2019-08-02 | 2024-11-29 | H Lundbeck As | Derivati alkohola kao otvarači kv7 kalijumovih kanala |
| CN114206328B (zh) * | 2019-08-02 | 2024-09-17 | H.隆德贝克有限公司 | 用于在癫痫或癫痫发作中使用的作为Kv7钾通道开放剂的醇衍生物 |
-
2020
- 2020-07-30 RS RS20241162A patent/RS66130B1/sr unknown
- 2020-07-30 PH PH1/2022/550192A patent/PH12022550192A1/en unknown
- 2020-07-30 HR HRP20241444TT patent/HRP20241444T1/hr unknown
- 2020-07-30 GE GEAP202415862A patent/GEAP202415862A/en unknown
- 2020-07-30 GE GEAP202015862A patent/GEP20247629B/en unknown
- 2020-07-30 CN CN202080051950.0A patent/CN114206830B/zh active Active
- 2020-07-30 MX MX2022001063A patent/MX2022001063A/es unknown
- 2020-07-30 EP EP20749879.1A patent/EP4007634B1/en active Active
- 2020-07-30 EP EP24203380.1A patent/EP4461725A3/en active Pending
- 2020-07-30 JP JP2022505198A patent/JP7720829B2/ja active Active
- 2020-07-30 SM SM20240445T patent/SMT202400445T1/it unknown
- 2020-07-30 PL PL20749879.1T patent/PL4007634T3/pl unknown
- 2020-07-30 AU AU2020325517A patent/AU2020325517B2/en active Active
- 2020-07-30 MA MA56708A patent/MA56708B1/fr unknown
- 2020-07-30 ES ES20749879T patent/ES2989376T3/es active Active
- 2020-07-30 HU HUE20749879A patent/HUE069310T2/hu unknown
- 2020-07-30 PE PE2022000184A patent/PE20220345A1/es unknown
- 2020-07-30 IL IL290193A patent/IL290193B2/en unknown
- 2020-07-30 CR CR20220028A patent/CR20220028A/es unknown
- 2020-07-30 WO PCT/EP2020/071520 patent/WO2021023617A1/en not_active Ceased
- 2020-07-30 CA CA3148719A patent/CA3148719A1/en active Pending
- 2020-07-30 BR BR112021006324A patent/BR112021006324A2/pt unknown
-
2021
- 2021-11-25 ZA ZA2021/09598A patent/ZA202109598B/en unknown
-
2022
- 2022-01-11 CO CONC2022/0000080A patent/CO2022000080A2/es unknown
- 2022-01-25 JO JOP/2022/0017A patent/JOP20220017A1/ar unknown
- 2022-01-27 CL CL2022000221A patent/CL2022000221A1/es unknown
- 2022-02-02 DO DO2022000026A patent/DOP2022000026A/es unknown
- 2022-02-04 EC ECSENADI20228993A patent/ECSP22008993A/es unknown
-
2025
- 2025-07-03 JP JP2025112976A patent/JP2025160211A/ja active Pending
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