JP2022542937A5 - - Google Patents

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Publication number
JP2022542937A5
JP2022542937A5 JP2022505602A JP2022505602A JP2022542937A5 JP 2022542937 A5 JP2022542937 A5 JP 2022542937A5 JP 2022505602 A JP2022505602 A JP 2022505602A JP 2022505602 A JP2022505602 A JP 2022505602A JP 2022542937 A5 JP2022542937 A5 JP 2022542937A5
Authority
JP
Japan
Prior art keywords
amino
methyl
propyl
benzothiazole
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022505602A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022542937A (ja
JP7646626B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2020/071179 external-priority patent/WO2021018857A1/en
Publication of JP2022542937A publication Critical patent/JP2022542937A/ja
Publication of JP2022542937A5 publication Critical patent/JP2022542937A5/ja
Application granted granted Critical
Publication of JP7646626B2 publication Critical patent/JP7646626B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022505602A 2019-07-29 2020-07-28 3,6-ジアミノ-ピリダジン-3-イル誘導体、それを含有する医薬組成物及びアポトーシス促進剤としてのその使用 Active JP7646626B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19188747.0 2019-07-29
EP19188747 2019-07-29
PCT/EP2020/071179 WO2021018857A1 (en) 2019-07-29 2020-07-28 3,6-diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their uses as pro-apoptotic agents

Publications (3)

Publication Number Publication Date
JP2022542937A JP2022542937A (ja) 2022-10-07
JP2022542937A5 true JP2022542937A5 (enExample) 2023-07-14
JP7646626B2 JP7646626B2 (ja) 2025-03-17

Family

ID=67514281

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022505602A Active JP7646626B2 (ja) 2019-07-29 2020-07-28 3,6-ジアミノ-ピリダジン-3-イル誘導体、それを含有する医薬組成物及びアポトーシス促進剤としてのその使用

Country Status (24)

Country Link
US (1) US20220289734A1 (enExample)
EP (1) EP4003988A1 (enExample)
JP (1) JP7646626B2 (enExample)
KR (1) KR20220042182A (enExample)
CN (1) CN114450283B (enExample)
AR (1) AR119493A1 (enExample)
AU (1) AU2020322072A1 (enExample)
BR (1) BR112022001330A2 (enExample)
CA (1) CA3148502A1 (enExample)
CL (1) CL2021003594A1 (enExample)
CO (1) CO2022000700A2 (enExample)
CR (1) CR20220014A (enExample)
DO (1) DOP2022000015A (enExample)
GE (2) GEAP202415866A (enExample)
IL (1) IL289932B2 (enExample)
JO (1) JOP20220006A1 (enExample)
MX (1) MX2022001161A (enExample)
PE (1) PE20220704A1 (enExample)
PH (1) PH12022550018A1 (enExample)
PY (1) PY2039849A (enExample)
SA (1) SA522431498B1 (enExample)
TW (1) TWI900486B (enExample)
UY (1) UY38809A (enExample)
WO (1) WO2021018857A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021386367A1 (en) * 2020-11-24 2023-06-22 Les Laboratoires Servier Bcl-xl inhibitor antibody-drug conjugates and methods of use thereof
JP2024505562A (ja) * 2021-02-02 2024-02-06 レス ラボラトイレス セルビエル 選択的bcl-xl protac化合物及び使用の方法
CN119562832A (zh) 2022-05-20 2025-03-04 诺华股份有限公司 Met bcl-xl抑制剂抗体-药物缀合物及其使用方法
AU2023271885A1 (en) 2022-05-20 2024-12-12 Les Laboratoires Servier Epha2 bcl-xl inhibitor antibody-drug conjugates and methods of use thereof
US20250387504A1 (en) 2022-05-20 2025-12-25 Novartis Ag Antibody-drug conjugates of antineoplastic compounds and methods of use thereof
PY24103486A (es) 2023-11-22 2025-06-06 Servier Lab Conjugados de anticuerpo anti-cd74-fármaco y métodos de uso de los mismos
AR134424A1 (es) 2023-11-22 2026-01-14 Novartis Ag Conjugados de anticuerpo anti-cd7-fármaco y métodos de uso de los mismos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003059354A2 (en) * 2001-12-21 2003-07-24 Bayer Pharmaceuticals Corporation Anti-angiogenesis combination therapies comprising pyridazine or pyridine derivatives
WO2009020603A2 (en) * 2007-08-08 2009-02-12 The Scripps Research Institute Upp amphiphilic alpha-helix mimetics
EA201001030A1 (ru) * 2007-12-19 2011-02-28 Амген Инк. Конденсированные соединения пиридина, пиримидина и триазина в качестве ингибиторов клеточного цикла
FR3015483B1 (fr) 2013-12-23 2016-01-01 Servier Lab Nouveaux derives de thienopyrimidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
SG11201709837RA (en) * 2015-05-29 2017-12-28 Teijin Pharma Ltd PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF

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