JP2022542937A5 - - Google Patents
Info
- Publication number
- JP2022542937A5 JP2022542937A5 JP2022505602A JP2022505602A JP2022542937A5 JP 2022542937 A5 JP2022542937 A5 JP 2022542937A5 JP 2022505602 A JP2022505602 A JP 2022505602A JP 2022505602 A JP2022505602 A JP 2022505602A JP 2022542937 A5 JP2022542937 A5 JP 2022542937A5
- Authority
- JP
- Japan
- Prior art keywords
- amino
- methyl
- propyl
- benzothiazole
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19188747.0 | 2019-07-29 | ||
| EP19188747 | 2019-07-29 | ||
| PCT/EP2020/071179 WO2021018857A1 (en) | 2019-07-29 | 2020-07-28 | 3,6-diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their uses as pro-apoptotic agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022542937A JP2022542937A (ja) | 2022-10-07 |
| JP2022542937A5 true JP2022542937A5 (enExample) | 2023-07-14 |
| JP7646626B2 JP7646626B2 (ja) | 2025-03-17 |
Family
ID=67514281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022505602A Active JP7646626B2 (ja) | 2019-07-29 | 2020-07-28 | ３，６－ジアミノ－ピリダジン－３－イル誘導体、それを含有する医薬組成物及びアポトーシス促進剤としてのその使用 |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US12649733B2 (enExample) |
| EP (1) | EP4003988B1 (enExample) |
| JP (1) | JP7646626B2 (enExample) |
| KR (1) | KR102987770B1 (enExample) |
| CN (1) | CN114450283B (enExample) |
| AR (1) | AR119493A1 (enExample) |
| AU (1) | AU2020322072B2 (enExample) |
| BR (1) | BR112022001330A2 (enExample) |
| CL (1) | CL2021003594A1 (enExample) |
| CO (1) | CO2022000700A2 (enExample) |
| CR (1) | CR20220014A (enExample) |
| DK (1) | DK4003988T3 (enExample) |
| DO (1) | DOP2022000015A (enExample) |
| ES (1) | ES3074241T3 (enExample) |
| FI (1) | FI4003988T3 (enExample) |
| GE (2) | GEP20247670B (enExample) |
| IL (1) | IL289932B2 (enExample) |
| JO (1) | JOP20220006A1 (enExample) |
| LT (1) | LT4003988T (enExample) |
| MA (1) | MA56644B1 (enExample) |
| MX (1) | MX2022001161A (enExample) |
| PE (1) | PE20220704A1 (enExample) |
| PH (1) | PH12022550018A1 (enExample) |
| PT (1) | PT4003988T (enExample) |
| PY (1) | PY2039849A (enExample) |
| SA (1) | SA522431498B1 (enExample) |
| TW (1) | TWI900486B (enExample) |
| UA (1) | UA130870C2 (enExample) |
| UY (1) | UY38809A (enExample) |
| WO (1) | WO2021018857A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116761635A (zh) * | 2020-11-24 | 2023-09-15 | 诺华股份有限公司 | Bcl-xl抑制剂抗体药物缀合物及其使用方法 |
| JP2024505562A (ja) * | 2021-02-02 | 2024-02-06 | レス ラボラトイレス セルビエル | 選択的ｂｃｌ－ｘｌ ｐｒｏｔａｃ化合物及び使用の方法 |
| EP4525925A1 (en) | 2022-05-20 | 2025-03-26 | Novartis AG | Epha2 bcl-xl inhibitor antibody-drug conjugates and methods of use thereof |
| CN119562832A (zh) | 2022-05-20 | 2025-03-04 | 诺华股份有限公司 | Met bcl-xl抑制剂抗体-药物缀合物及其使用方法 |
| IL317101A (en) | 2022-05-20 | 2025-01-01 | Novartis Ag | Antibody-drug conjugates of anticancer compounds and methods of using them |
| AR134424A1 (es) | 2023-11-22 | 2026-01-14 | Novartis Ag | Conjugados de anticuerpo anti-cd7-fármaco y métodos de uso de los mismos |
| UY40985A (es) | 2023-11-22 | 2025-06-30 | Servier Lab | Conjugados de anticuerpo anti-cd74-fármaco y métodos de uso de los mismos |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2471314A1 (en) * | 2001-12-21 | 2003-07-24 | Bayer Pharmaceuticals Corporation | Anti-angiogenesis combination therapies comprising pyridazine or pyridine derivatives |
| WO2009020603A2 (en) * | 2007-08-08 | 2009-02-12 | The Scripps Research Institute | Upp amphiphilic alpha-helix mimetics |
| AU2008343932B2 (en) * | 2007-12-19 | 2013-08-15 | Amgen Inc. | Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors |
| FR3015483B1 (fr) | 2013-12-23 | 2016-01-01 | Servier Lab | Nouveaux derives de thienopyrimidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| EP3229844B1 (en) | 2014-12-09 | 2020-03-04 | AbbVie Inc. | Antibody drug conjugates with cell permeable bcl-xl inhibitors |
| JP2018502839A (ja) | 2014-12-09 | 2018-02-01 | アッヴィ・インコーポレイテッド | Ｂｃｌ−ｘＬ阻害性化合物およびこれを含む抗体薬物コンジュゲート |
| RU2017123942A (ru) | 2014-12-09 | 2019-01-11 | Эббви Инк. | Ингибирующие bcl-xl соединения, обладающие низкой клеточной проницаемостью, и коньюгаты антитело-лекарственное средство, включающие их |
| US10124004B2 (en) * | 2015-05-29 | 2018-11-13 | Teijin Pharma Limited | Pyrido[3,4-d]pyrimidine derivative and pharmaceutically acceptable salt thereof |
| MX2018015284A (es) | 2016-06-08 | 2019-09-18 | Abbvie Inc | Conjugados de anticuerpo anti-egfr y fármaco. |
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2020
- 2020-07-27 AR ARP200102095A patent/AR119493A1/es unknown
- 2020-07-28 LT LTEPPCT/EP2020/071179T patent/LT4003988T/lt unknown
- 2020-07-28 UA UAA202200226A patent/UA130870C2/uk unknown
- 2020-07-28 WO PCT/EP2020/071179 patent/WO2021018857A1/en not_active Ceased
- 2020-07-28 GE GEAP202015866A patent/GEP20247670B/en unknown
- 2020-07-28 MX MX2022001161A patent/MX2022001161A/es unknown
- 2020-07-28 PE PE2022000148A patent/PE20220704A1/es unknown
- 2020-07-28 CN CN202080068042.2A patent/CN114450283B/zh active Active
- 2020-07-28 JP JP2022505602A patent/JP7646626B2/ja active Active
- 2020-07-28 ES ES20749833T patent/ES3074241T3/es active Active
- 2020-07-28 AU AU2020322072A patent/AU2020322072B2/en active Active
- 2020-07-28 PT PT207498338T patent/PT4003988T/pt unknown
- 2020-07-28 MA MA56644A patent/MA56644B1/fr unknown
- 2020-07-28 GE GEAP202415866A patent/GEAP202415866A/en unknown
- 2020-07-28 PH PH1/2022/550018A patent/PH12022550018A1/en unknown
- 2020-07-28 JO JOP/2022/0006A patent/JOP20220006A1/ar unknown
- 2020-07-28 BR BR112022001330A patent/BR112022001330A2/pt unknown
- 2020-07-28 CR CR20220014A patent/CR20220014A/es unknown
- 2020-07-28 US US17/630,655 patent/US12649733B2/en active Active
- 2020-07-28 KR KR1020227006624A patent/KR102987770B1/ko active Active
- 2020-07-28 FI FIEP20749833.8T patent/FI4003988T3/fi active
- 2020-07-28 IL IL289932A patent/IL289932B2/en unknown
- 2020-07-28 EP EP20749833.8A patent/EP4003988B1/en active Active
- 2020-07-28 TW TW109125418A patent/TWI900486B/zh active
- 2020-07-28 UY UY0001038809A patent/UY38809A/es active IP Right Grant
- 2020-07-28 DK DK20749833.8T patent/DK4003988T3/da active
- 2020-07-28 PY PY202002039849A patent/PY2039849A/es unknown
-
2021
- 2021-12-30 CL CL2021003594A patent/CL2021003594A1/es unknown
-
2022
- 2022-01-25 DO DO2022000015A patent/DOP2022000015A/es unknown
- 2022-01-26 CO CONC2022/0000700A patent/CO2022000700A2/es unknown
- 2022-01-26 SA SA522431498A patent/SA522431498B1/ar unknown