JP2022541459A5 - - Google Patents
Info
- Publication number
- JP2022541459A5 JP2022541459A5 JP2022502422A JP2022502422A JP2022541459A5 JP 2022541459 A5 JP2022541459 A5 JP 2022541459A5 JP 2022502422 A JP2022502422 A JP 2022502422A JP 2022502422 A JP2022502422 A JP 2022502422A JP 2022541459 A5 JP2022541459 A5 JP 2022541459A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide according
- subject
- conjugated polypeptide
- soluble
- sequence numbers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962874724P | 2019-07-16 | 2019-07-16 | |
| US62/874,724 | 2019-07-16 | ||
| PCT/US2020/042161 WO2021011673A2 (en) | 2019-07-16 | 2020-07-15 | Neutralizing anti-amyloid beta antibodies for the treatment of alzheimer's disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022541459A JP2022541459A (ja) | 2022-09-26 |
| JP2022541459A5 true JP2022541459A5 (cg-RX-API-DMAC7.html) | 2023-07-24 |
| JP7685985B2 JP7685985B2 (ja) | 2025-05-30 |
Family
ID=71895293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022502422A Active JP7685985B2 (ja) | 2019-07-16 | 2020-07-15 | アルツハイマー病の処置のための中和抗アミロイドベータ抗体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US12630615B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3999532A2 (cg-RX-API-DMAC7.html) |
| JP (1) | JP7685985B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20220034857A (cg-RX-API-DMAC7.html) |
| CN (3) | CN121800915A (cg-RX-API-DMAC7.html) |
| CA (2) | CA3313684A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2021011673A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111201030B (zh) | 2017-07-25 | 2024-11-01 | 真和制药有限公司 | 通过阻断tim-3和其配体的相互作用治疗癌症 |
| KR20210124308A (ko) | 2019-01-30 | 2021-10-14 | 트루바인딩 아이엔씨. | 항-gal3 항체 및 이의 용도 |
| MX2022014786A (es) | 2020-05-26 | 2023-01-16 | Truebinding Inc | Metodos para tratar enfermedades inflamatorias mediante el bloqueo de galectina-3. |
| WO2026082154A1 (en) * | 2024-10-18 | 2026-04-23 | Lepu Biopharma Co., Ltd. | Anti-beta amyloid antibodies and uses thereof |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| WO1993008829A1 (en) | 1991-11-04 | 1993-05-13 | The Regents Of The University Of California | Compositions that mediate killing of hiv-infected cells |
| CA2126967A1 (en) | 1992-11-04 | 1994-05-11 | Anna M. Wu | Novel antibody construct |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| AU5545596A (en) | 1995-04-28 | 1996-11-18 | Medtronic, Inc. | Intraparenchymal infusion catheter system |
| US5989830A (en) | 1995-10-16 | 1999-11-23 | Unilever Patent Holdings Bv | Bifunctional or bivalent antibody fragment analogue |
| GB9524973D0 (en) | 1995-12-06 | 1996-02-07 | Lynxvale Ltd | Viral vectors |
| US5735814A (en) | 1996-04-30 | 1998-04-07 | Medtronic, Inc. | Techniques of treating neurodegenerative disorders by brain infusion |
| US20030068316A1 (en) | 1997-02-05 | 2003-04-10 | Klein William L. | Anti-ADDL antibodies and uses thereof |
| EP0979281B1 (en) | 1997-05-02 | 2005-07-20 | Genentech, Inc. | A method for making multispecific antibodies having heteromultimeric and common components |
| AU2001270609A1 (en) | 2000-06-30 | 2002-01-14 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Heterodimeric fusion proteins |
| JP2006508072A (ja) * | 2002-10-01 | 2006-03-09 | ノースウエスタン ユニバーシティ | アミロイドベータ由来拡散性リガンド（ＡＤＤＬｓ）、ＡＤＤＬ代替物、ＡＤＤＬ結合性分子、およびそれらの使用 |
| US20160213794A1 (en) * | 2002-10-01 | 2016-07-28 | Northwestern University | Amyloid beta-derived diffusible ligands (addls), addl-surrogates, addl-binding molecules and uses thereof |
| AU2004266159A1 (en) | 2003-08-22 | 2005-03-03 | Biogen Idec Ma Inc. | Improved antibodies having altered effector function and methods for making the same |
| KR101374454B1 (ko) | 2005-03-31 | 2014-03-17 | 추가이 세이야쿠 가부시키가이샤 | 회합제어에 의한 폴리펩티드 제조방법 |
| US7612181B2 (en) | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
| PE20090329A1 (es) | 2007-05-30 | 2009-03-27 | Abbott Lab | Anticuerpos humanizados contra el globulomero ab(20-42) y sus usos |
| HRP20150086T1 (xx) * | 2007-06-12 | 2015-02-27 | Ac Immune S.A. | Humanizirana antitijela za beta amiloid |
| EP2050764A1 (en) | 2007-10-15 | 2009-04-22 | sanofi-aventis | Novel polyvalent bispecific antibody format and uses thereof |
| WO2011133919A1 (en) * | 2010-04-22 | 2011-10-27 | Janssen Alzheimer Immunotherapy | Use of tau to monitor immunotherapy |
| EP3663318A1 (en) | 2008-01-07 | 2020-06-10 | Amgen Inc. | Method for making antibody fc-heterodimeric molecules using electrostatic steering effects |
| US9221902B2 (en) * | 2008-11-07 | 2015-12-29 | Fabrus, Inc. | Combinatorial antibody libraries and uses thereof |
| US20130115227A1 (en) * | 2010-07-14 | 2013-05-09 | Renee C. Gaspar | Anti-addl monoclonal antibody and uses thereof |
| KR102308915B1 (ko) * | 2012-10-15 | 2021-10-06 | 메디뮨 리미티드 | 아밀로이드 베타에 대한 항체 |
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2020
- 2020-07-15 CA CA3313684A patent/CA3313684A1/en active Pending
- 2020-07-15 CN CN202511495657.4A patent/CN121800915A/zh active Pending
- 2020-07-15 EP EP20750124.8A patent/EP3999532A2/en active Pending
- 2020-07-15 JP JP2022502422A patent/JP7685985B2/ja active Active
- 2020-07-15 CN CN202080063538.0A patent/CN115175932B/zh active Active
- 2020-07-15 US US17/624,309 patent/US12630615B2/en active Active
- 2020-07-15 KR KR1020227004730A patent/KR20220034857A/ko active Pending
- 2020-07-15 WO PCT/US2020/042161 patent/WO2021011673A2/en not_active Ceased
- 2020-07-15 CA CA3147239A patent/CA3147239A1/en active Pending
- 2020-07-15 CN CN202511495659.3A patent/CN121949538A/zh active Pending