JP2022540993A5 - - Google Patents
Info
- Publication number
- JP2022540993A5 JP2022540993A5 JP2022500671A JP2022500671A JP2022540993A5 JP 2022540993 A5 JP2022540993 A5 JP 2022540993A5 JP 2022500671 A JP2022500671 A JP 2022500671A JP 2022500671 A JP2022500671 A JP 2022500671A JP 2022540993 A5 JP2022540993 A5 JP 2022540993A5
- Authority
- JP
- Japan
- Prior art keywords
- antisense compound
- salt
- administered
- dose
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023077805A JP7665678B2 (ja) | 2019-07-19 | 2023-05-10 | 脊髄性筋萎縮症を処置または予防する方法 |
| JP2025064592A JP2025096486A (ja) | 2019-07-19 | 2025-04-09 | 脊髄性筋萎縮症を処置または予防する方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962876360P | 2019-07-19 | 2019-07-19 | |
| US62/876,360 | 2019-07-19 | ||
| PCT/US2020/042312 WO2021016032A1 (en) | 2019-07-19 | 2020-07-16 | Methods of treating or preventing spinal muscular atrophy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023077805A Division JP7665678B2 (ja) | 2019-07-19 | 2023-05-10 | 脊髄性筋萎縮症を処置または予防する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022540993A JP2022540993A (ja) | 2022-09-21 |
| JP2022540993A5 true JP2022540993A5 (https=) | 2023-03-10 |
| JP7279253B2 JP7279253B2 (ja) | 2023-05-22 |
Family
ID=71995097
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022500671A Active JP7279253B2 (ja) | 2019-07-19 | 2020-07-16 | 脊髄性筋萎縮症を処置または予防する方法 |
| JP2023077805A Active JP7665678B2 (ja) | 2019-07-19 | 2023-05-10 | 脊髄性筋萎縮症を処置または予防する方法 |
| JP2025064592A Pending JP2025096486A (ja) | 2019-07-19 | 2025-04-09 | 脊髄性筋萎縮症を処置または予防する方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023077805A Active JP7665678B2 (ja) | 2019-07-19 | 2023-05-10 | 脊髄性筋萎縮症を処置または予防する方法 |
| JP2025064592A Pending JP2025096486A (ja) | 2019-07-19 | 2025-04-09 | 脊髄性筋萎縮症を処置または予防する方法 |
Country Status (33)
| Country | Link |
|---|---|
| US (3) | US20220325282A1 (https=) |
| EP (2) | EP4335503A3 (https=) |
| JP (3) | JP7279253B2 (https=) |
| KR (1) | KR20220042113A (https=) |
| CN (1) | CN114302727A (https=) |
| AR (1) | AR119430A1 (https=) |
| AU (1) | AU2020316997A1 (https=) |
| BR (1) | BR112022000870A2 (https=) |
| CA (1) | CA3149906A1 (https=) |
| CL (1) | CL2021003602A1 (https=) |
| CO (1) | CO2022001354A2 (https=) |
| CR (1) | CR20220071A (https=) |
| DK (1) | DK3999643T5 (https=) |
| ES (1) | ES2966791T3 (https=) |
| FI (1) | FI3999643T3 (https=) |
| HR (1) | HRP20231515T1 (https=) |
| HU (1) | HUE064071T2 (https=) |
| IL (1) | IL289745A (https=) |
| JO (2) | JOP20220007A1 (https=) |
| LT (1) | LT3999643T (https=) |
| MA (1) | MA62935B1 (https=) |
| MD (1) | MD3999643T2 (https=) |
| MX (1) | MX2022000441A (https=) |
| PE (1) | PE20220941A1 (https=) |
| PH (1) | PH12022550114A1 (https=) |
| PL (1) | PL3999643T3 (https=) |
| PT (1) | PT3999643T (https=) |
| RS (1) | RS64879B1 (https=) |
| SI (1) | SI3999643T1 (https=) |
| SM (1) | SMT202300442T1 (https=) |
| TW (2) | TW202438086A (https=) |
| UY (1) | UY38790A (https=) |
| WO (1) | WO2021016032A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3797780B1 (en) | 2014-04-17 | 2022-09-14 | Biogen MA Inc. | Compositions and methods for modulation of smn2 splicing in a subject |
| US10436802B2 (en) | 2014-09-12 | 2019-10-08 | Biogen Ma Inc. | Methods for treating spinal muscular atrophy |
| PT3999643T (pt) | 2019-07-19 | 2023-12-11 | Biogen Ma Inc | Métodos de tratamento da atrofia muscular espinhal |
| WO2024138018A1 (en) * | 2022-12-23 | 2024-06-27 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Treatment of gemin5-mediated disorders |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3470072A1 (en) * | 2005-06-23 | 2019-04-17 | Biogen MA Inc. | Compositions and methods for modulation of smn2 splicing |
| WO2008157753A1 (en) * | 2007-06-21 | 2008-12-24 | Sma Foundation | Methods of treatment for spinal muscular atrophy |
| ES2699827T3 (es) | 2009-06-17 | 2019-02-13 | Biogen Ma Inc | Composiciones y métodos para la modulación de corte y empalme de SMN2 en un sujeto |
| WO2011032109A1 (en) | 2009-09-11 | 2011-03-17 | Sma Foundation | Biomarkers for spinal muscular atrophy |
| EP2714037B1 (en) * | 2011-05-25 | 2016-07-13 | Université Paris Descartes | Erk inhibitors for use in treating spinal muscular atrophy |
| WO2014110291A1 (en) | 2013-01-09 | 2014-07-17 | Isis Pharmaceuticals, Inc. | Compositions and methods for modulation of smn2 splicing in a subject |
| US10436802B2 (en) | 2014-09-12 | 2019-10-08 | Biogen Ma Inc. | Methods for treating spinal muscular atrophy |
| EP3484524B1 (en) * | 2016-07-15 | 2022-11-09 | Ionis Pharmaceuticals, Inc. | Compounds and methods for modulation of smn2 |
| TW201927241A (zh) | 2017-12-21 | 2019-07-16 | 瑞士商赫孚孟拉羅股份公司 | 用於肌肉失能之數位生物標記 |
| CN119679944A (zh) | 2018-01-25 | 2025-03-25 | 渤健马萨诸塞州股份有限公司 | 治疗脊髓性肌萎缩症的方法 |
| IT201800004359A1 (it) | 2018-04-10 | 2019-10-10 | IDENTIFICAZIONE DI miRNA MUSCOLARI COME BIOMARCATORI E TRATTAMENTO CO-ADIUVANTE PER L’ATROFIA MUSCOLARE SPINALE | |
| US20210308281A1 (en) * | 2018-08-15 | 2021-10-07 | Biogen Ma Inc. | Combination therapy for spinal muscular atrophy |
| PT3999643T (pt) | 2019-07-19 | 2023-12-11 | Biogen Ma Inc | Métodos de tratamento da atrofia muscular espinhal |
-
2020
- 2020-07-16 PT PT207535568T patent/PT3999643T/pt unknown
- 2020-07-16 EP EP23210526.2A patent/EP4335503A3/en active Pending
- 2020-07-16 BR BR112022000870A patent/BR112022000870A2/pt unknown
- 2020-07-16 ES ES20753556T patent/ES2966791T3/es active Active
- 2020-07-16 PH PH1/2022/550114A patent/PH12022550114A1/en unknown
- 2020-07-16 SI SI202030323T patent/SI3999643T1/sl unknown
- 2020-07-16 DK DK20753556.8T patent/DK3999643T5/da active
- 2020-07-16 MX MX2022000441A patent/MX2022000441A/es unknown
- 2020-07-16 LT LTEPPCT/US2020/042312T patent/LT3999643T/lt unknown
- 2020-07-16 JP JP2022500671A patent/JP7279253B2/ja active Active
- 2020-07-16 FI FIEP20753556.8T patent/FI3999643T3/fi active
- 2020-07-16 HR HRP20231515TT patent/HRP20231515T1/hr unknown
- 2020-07-16 US US17/626,324 patent/US20220325282A1/en not_active Abandoned
- 2020-07-16 AU AU2020316997A patent/AU2020316997A1/en active Pending
- 2020-07-16 HU HUE20753556A patent/HUE064071T2/hu unknown
- 2020-07-16 EP EP20753556.8A patent/EP3999643B1/en active Active
- 2020-07-16 PL PL20753556.8T patent/PL3999643T3/pl unknown
- 2020-07-16 RS RS20231128A patent/RS64879B1/sr unknown
- 2020-07-16 UY UY0001038790A patent/UY38790A/es not_active Application Discontinuation
- 2020-07-16 WO PCT/US2020/042312 patent/WO2021016032A1/en not_active Ceased
- 2020-07-16 SM SM20230442T patent/SMT202300442T1/it unknown
- 2020-07-16 MA MA62935A patent/MA62935B1/fr unknown
- 2020-07-16 CR CR20220071A patent/CR20220071A/es unknown
- 2020-07-16 CN CN202080049461.1A patent/CN114302727A/zh active Pending
- 2020-07-16 MD MDE20220574T patent/MD3999643T2/ro unknown
- 2020-07-16 CA CA3149906A patent/CA3149906A1/en active Pending
- 2020-07-16 KR KR1020227001151A patent/KR20220042113A/ko active Pending
- 2020-07-16 PE PE2021002322A patent/PE20220941A1/es unknown
- 2020-07-17 TW TW113114478A patent/TW202438086A/zh unknown
- 2020-07-17 AR ARP200102019A patent/AR119430A1/es unknown
- 2020-07-17 TW TW109124224A patent/TWI841762B/zh active
-
2021
- 2021-12-31 CL CL2021003602A patent/CL2021003602A1/es unknown
-
2022
- 2022-01-10 IL IL289745A patent/IL289745A/en unknown
- 2022-01-16 JO JOP/2022/0007A patent/JOP20220007A1/ar unknown
- 2022-02-10 CO CONC2022/0001354A patent/CO2022001354A2/es unknown
-
2023
- 2023-05-10 JP JP2023077805A patent/JP7665678B2/ja active Active
-
2024
- 2024-05-10 US US18/661,339 patent/US20240318182A1/en not_active Abandoned
-
2025
- 2025-04-07 US US19/172,111 patent/US20250230440A1/en active Pending
- 2025-04-09 JP JP2025064592A patent/JP2025096486A/ja active Pending
- 2025-05-05 JO JOJO/P/2025/0103A patent/JOP20250103A1/ar unknown
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