JP2022538886A5 - - Google Patents
Info
- Publication number
- JP2022538886A5 JP2022538886A5 JP2021577915A JP2021577915A JP2022538886A5 JP 2022538886 A5 JP2022538886 A5 JP 2022538886A5 JP 2021577915 A JP2021577915 A JP 2021577915A JP 2021577915 A JP2021577915 A JP 2021577915A JP 2022538886 A5 JP2022538886 A5 JP 2022538886A5
- Authority
- JP
- Japan
- Prior art keywords
- rodent
- immunoglobulin
- canine
- transgenic
- gene segment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962869435P | 2019-07-01 | 2019-07-01 | |
| US62/869,435 | 2019-07-01 | ||
| PCT/US2020/040282 WO2021003149A1 (en) | 2019-07-01 | 2020-06-30 | Transgenic mammals and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022538886A JP2022538886A (ja) | 2022-09-06 |
| JP2022538886A5 true JP2022538886A5 (https=) | 2023-07-07 |
| JP7744248B2 JP7744248B2 (ja) | 2025-09-25 |
Family
ID=71784658
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021577915A Active JP7744248B2 (ja) | 2019-07-01 | 2020-06-30 | トランスジェニック哺乳動物およびその使用法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20210000087A1 (https=) |
| EP (1) | EP3993622A1 (https=) |
| JP (1) | JP7744248B2 (https=) |
| CN (1) | CN114502725B (https=) |
| AU (1) | AU2020299569A1 (https=) |
| CA (1) | CA3144956A1 (https=) |
| IL (1) | IL289473A (https=) |
| WO (1) | WO2021003149A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022235759A1 (en) * | 2021-05-05 | 2022-11-10 | Trianni, Inc. | Transgenic rodents expressing chimeric equine-rodent antibodies and methods of use thereof |
| GB202107372D0 (en) | 2021-05-24 | 2021-07-07 | Petmedix Ltd | Animal models and therapeutics molecules |
| US20250320520A1 (en) | 2021-10-01 | 2025-10-16 | Abcellera Biologics Inc. | Trangenic rodents for cell line identification and enrichment |
| KR20240110577A (ko) * | 2021-11-10 | 2024-07-15 | 트리아니, 인코포레이티드 | 유전자이식 포유동물 및 이의 사용 방법 |
| GB202209247D0 (en) | 2022-06-23 | 2022-08-10 | Petmedix Ltd | Animal models and therapeutic molecules |
| GB202217978D0 (en) * | 2022-11-30 | 2023-01-11 | Petmedix Ltd | Rodents expressing a common light chain |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1293460C (en) | 1985-10-07 | 1991-12-24 | Brian Lee Sauer | Site-specific recombination of dna in yeast |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5175384A (en) | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
| GB8904009D0 (en) | 1989-02-22 | 1989-04-05 | Celltech Ltd | Vector |
| US6689610B1 (en) | 1989-08-22 | 2004-02-10 | University Of Utah Research Foundation | Cells and non-human organisms containing predetermined genomic modifications and positive-negative selection methods and vectors for making same |
| US5464764A (en) | 1989-08-22 | 1995-11-07 | University Of Utah Research Foundation | Positive-negative selection methods and vectors |
| US6673986B1 (en) | 1990-01-12 | 2004-01-06 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5789650A (en) | 1990-08-29 | 1998-08-04 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5877397A (en) | 1990-08-29 | 1999-03-02 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5874299A (en) | 1990-08-29 | 1999-02-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| DE69133557D1 (de) | 1990-08-29 | 2007-03-15 | Pharming Intellectual Pty Bv | Homologe rekombination in säugetier-zellen |
| US7041871B1 (en) | 1995-10-10 | 2006-05-09 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| WO1992015694A1 (en) | 1991-03-08 | 1992-09-17 | The Salk Institute For Biological Studies | Flp-mediated gene modification in mammalian cells, and compositions and cells useful therefor |
| DE4228162C1 (de) | 1992-08-25 | 1994-01-13 | Rajewsky Klaus Dr | Verfahren zum Ersetzen homologer Genabschnitte aus Säugern in der Keimbahn von nicht-menschlichen Säugern |
| US5593598A (en) | 1994-04-20 | 1997-01-14 | Mcginness; Michael P. | Method and apparatus for closed loop recycling of contaminated cleaning solution |
| US6130364A (en) | 1995-03-29 | 2000-10-10 | Abgenix, Inc. | Production of antibodies using Cre-mediated site-specific recombination |
| US6091001A (en) | 1995-03-29 | 2000-07-18 | Abgenix, Inc. | Production of antibodies using Cre-mediated site-specific recombination |
| CA2722378C (en) | 1996-12-03 | 2015-02-03 | Amgen Fremont Inc. | Human antibodies that bind tnf.alpha. |
| US6774279B2 (en) | 1997-05-30 | 2004-08-10 | Carnegie Institution Of Washington | Use of FLP recombinase in mice |
| FR2814642B1 (fr) | 2000-10-03 | 2005-07-01 | Ass Pour Le Dev De La Rech En | Souris transgenique pour la recombinaison ciblee mediee par la cre-er modifiee |
| US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| US7422889B2 (en) | 2004-10-29 | 2008-09-09 | Stowers Institute For Medical Research | Dre recombinase and recombinase systems employing Dre recombinase |
| EP2147594B1 (en) * | 2008-06-27 | 2013-11-13 | Merus B.V. | Antibody producing non-human mammals |
| US9445581B2 (en) * | 2012-03-28 | 2016-09-20 | Kymab Limited | Animal models and therapeutic molecules |
| US10662256B2 (en) * | 2010-07-26 | 2020-05-26 | Trianni, Inc. | Transgenic mammals and methods of use thereof |
| CN103025884B (zh) * | 2010-07-26 | 2015-11-25 | 特里安尼公司 | 转基因动物和使用方法 |
| US9253965B2 (en) * | 2012-03-28 | 2016-02-09 | Kymab Limited | Animal models and therapeutic molecules |
| GB2561352B (en) * | 2017-04-10 | 2023-01-18 | Genome Res Ltd | Animal models and therapeutic molecules |
| HUE060608T2 (hu) | 2017-12-05 | 2023-03-28 | Regeneron Pharma | Genetikailag módosított immunglobulin lambda könnyûlánccal rendelkezõ egerek és azok alkalmazása |
| GB2578867A (en) * | 2018-10-09 | 2020-06-03 | Genome Res Ltd | Animal models and therapeutic molecules |
-
2020
- 2020-06-30 CN CN202080059181.9A patent/CN114502725B/zh active Active
- 2020-06-30 JP JP2021577915A patent/JP7744248B2/ja active Active
- 2020-06-30 EP EP20745375.4A patent/EP3993622A1/en active Pending
- 2020-06-30 CA CA3144956A patent/CA3144956A1/en active Pending
- 2020-06-30 US US16/916,492 patent/US20210000087A1/en not_active Abandoned
- 2020-06-30 AU AU2020299569A patent/AU2020299569A1/en active Pending
- 2020-06-30 WO PCT/US2020/040282 patent/WO2021003149A1/en not_active Ceased
-
2021
- 2021-12-28 IL IL289473A patent/IL289473A/en unknown
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