JP2022538312A5 - - Google Patents

Info

Publication number
JP2022538312A5
JP2022538312A5 JP2021577497A JP2021577497A JP2022538312A5 JP 2022538312 A5 JP2022538312 A5 JP 2022538312A5 JP 2021577497 A JP2021577497 A JP 2021577497A JP 2021577497 A JP2021577497 A JP 2021577497A JP 2022538312 A5 JP2022538312 A5 JP 2022538312A5
Authority
JP
Japan
Prior art keywords
triazole
alkyl
group
substituted
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP2021577497A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022538312A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2020/068834 external-priority patent/WO2021004940A1/en
Publication of JP2022538312A publication Critical patent/JP2022538312A/ja
Publication of JP2022538312A5 publication Critical patent/JP2022538312A5/ja
Abandoned legal-status Critical Current

Links

JP2021577497A 2019-07-05 2020-07-03 ガレクチンの新規なガラクトシド阻害剤 Abandoned JP2022538312A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19184577 2019-07-05
EP19184577.5 2019-07-05
PCT/EP2020/068834 WO2021004940A1 (en) 2019-07-05 2020-07-03 Novel galactoside inhibitor of galectins

Publications (2)

Publication Number Publication Date
JP2022538312A JP2022538312A (ja) 2022-09-01
JP2022538312A5 true JP2022538312A5 (https=) 2023-07-07

Family

ID=67184824

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021577497A Abandoned JP2022538312A (ja) 2019-07-05 2020-07-03 ガレクチンの新規なガラクトシド阻害剤

Country Status (6)

Country Link
US (1) US12441755B2 (https=)
EP (1) EP3994135A1 (https=)
JP (1) JP2022538312A (https=)
CN (1) CN114450282A (https=)
CA (1) CA3143078A1 (https=)
WO (1) WO2021004940A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022508720A (ja) * 2018-10-15 2022-01-19 ガレクト バイオテック エービー ガレクチンのガラクトシド阻害剤
CN114206893A (zh) 2019-08-09 2022-03-18 爱杜西亚药品有限公司 (杂)芳基-甲基-硫代-β-D-吡喃半乳糖苷衍生物
WO2021028323A1 (en) 2019-08-09 2021-02-18 Idorsia Pharmaceuticals Ltd (2-acetamidyl)thio-beta-d-galactopyranoside derivatives
MA56883B1 (fr) 2019-08-15 2025-04-30 Idorsia Pharmaceuticals Ltd Dérivés de 2-hydroxycycloalcane-1-carbamoyle
CN114585619B (zh) 2019-08-29 2024-09-27 爱杜西亚药品有限公司 α-D-吡喃半乳糖苷衍生物
US12312362B2 (en) 2020-10-06 2025-05-27 Idorsia Pharmaceuticals Ltd Spiro derivatives of Alpha-D-galactopyranosides
EP4237419A1 (en) 2020-11-02 2023-09-06 Idorsia Pharmaceuticals Ltd Galectin-3 inhibiting 2-hydroxycycloalkane-1 -carbamoyl derivatives
CA3205493A1 (en) * 2020-12-22 2022-06-30 Galecto Biotech Ab Novel galactoside inhibitor of galectins
CN116806219A (zh) 2021-02-09 2023-09-26 爱杜西亚药品有限公司 羟基杂环烷-氨甲酰基衍生物
RS67032B1 (sr) 2021-03-03 2025-08-29 Idorsia Pharmaceuticals Ltd Alfa-d-galaktopiranozidni derivati supstituisani triazolil-metilom
EP4337694A1 (en) 2021-05-12 2024-03-20 Dana-Farber Cancer Institute, Inc. Lag3 and gal3 inhibitory agents, xbp1, cs1, and cd138 peptides, and methods of use thereof
WO2023118267A1 (en) * 2021-12-22 2023-06-29 Galecto Biotech Ab Novel galactoside inhibitor of galectins

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6849607B2 (en) 2001-05-09 2005-02-01 Health Research, Inc. Galectin recognized photosensitizers for photodynamic therapy
SE0401301D0 (sv) 2004-05-21 2004-05-21 Forskarpatent I Syd Ab Novel 3-triazolyl-galactoside inhibitors of galectins
SE0401300D0 (sv) 2004-05-21 2004-05-21 Forskarpatent I Syd Ab Novel Galactoside Inhibitors of Galectins
ES2652488T3 (es) 2009-04-28 2018-02-02 Galecto Biotech Ab Nuevos inhibidores de galactósidos de galectinas
DK2906227T3 (en) 2012-10-10 2018-12-10 Galectin Therapeutics Inc GALACTOSE-CONTAINING CARBOHYDRATE COMPOUNDS FOR THE TREATMENT OF DIABETIC Nephropathy
CN104755088A (zh) 2012-10-31 2015-07-01 格莱克特生物技术公司 半乳凝集素-3的半乳糖苷抑制剂及其用于治疗肺纤维化的应用
CA2970062C (en) * 2015-01-30 2023-02-28 Galecto Biotech Ab Alpha-d-galactoside inhibitors of galectins
WO2019067702A1 (en) * 2017-09-27 2019-04-04 Bristol-Myers Squibb Company INHIBITORS WITH SMALL MOLECULES OF GALECTIN-3
US11072626B2 (en) * 2017-10-11 2021-07-27 Bristol-Myers Squibb Company Small molecule inhibitors of Galectin-3

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