JP2022537877A - アプレミラストおよびｔｙｋ２阻害剤を含む併用療法 - Google Patents
アプレミラストおよびｔｙｋ２阻害剤を含む併用療法 Download PDFInfo
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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| TW202246232A (zh) | 2021-02-19 | 2022-12-01 | 英商蘇多生物科學有限公司 | Ｔｙｋ２抑制劑及其用途 |
| AU2022350509A1 (en) * | 2021-09-23 | 2024-04-04 | Bristol-Myers Squibb Company | Methods of treating hair-loss disorders with tyk2 inhibitors |
| CA3236262A1 (en) | 2021-10-25 | 2023-05-04 | Isaac Marx | Tyk2 degraders and uses thereof |
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| US20160045475A1 (en) * | 2014-08-15 | 2016-02-18 | Celgene Corporation | Methods for the treatment of diseases ameliorated by pde4 inhibition using dosage titration of apremilast |
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| US7893101B2 (en) | 2002-03-20 | 2011-02-22 | Celgene Corporation | Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof |
| GB0709031D0 (en) | 2007-05-10 | 2007-06-20 | Sareum Ltd | Pharmaceutical compounds |
| GB0820819D0 (en) | 2008-11-13 | 2008-12-24 | Sareum Ltd | Pharmaceutical compounds |
| US8367689B2 (en) * | 2009-05-06 | 2013-02-05 | Portola Pharmaceuticals, Inc. | Inhibitors of JAK |
| AU2011328237A1 (en) | 2010-11-09 | 2013-05-23 | Cellzome Limited | Pyridine compounds and aza analogues thereof as TYK2 inhibitors |
| UA113750C2 (xx) | 2011-12-27 | 2017-03-10 | Склад (+)-2-$1-(3-етокси-4-метоксифеніл)-2-метансульфонілетил]-4-ацетиламіноізоіндолін-1,3-діону | |
| RU2627661C2 (ru) | 2012-01-10 | 2017-08-09 | Ф. Хоффманн-Ля Рош Аг | Соединения пиридазинамида и их применение в качестве ингибиторов тирозинкиназы селезенки (syk) |
| EP2832734A4 (en) | 2012-03-28 | 2015-08-26 | Takeda Pharmaceutical | HETEROCYCLIC CONNECTION |
| US9296725B2 (en) | 2012-05-24 | 2016-03-29 | Cellzome Limited | Heterocyclyl pyrimidine analogues as TYK2 inhibitors |
| UY35126A (es) | 2012-11-08 | 2014-05-30 | Bristol Myers Squibb Co | Ojo es alfa |
| EA028052B1 (ru) * | 2012-11-08 | 2017-10-31 | Бристол-Майерс Сквибб Компани | АЛКИЛАМИДЗАМЕЩЁННЫЕ ПИРИМИДИНОВЫЕ СОЕДИНЕНИЯ, ПРИГОДНЫЕ ДЛЯ МОДУЛЯЦИИ IL-12, IL-23 И/ИЛИ IFNα |
| WO2014151180A1 (en) * | 2013-03-14 | 2014-09-25 | Celgene Corporation | Treatment of psoriatic arthritis using apremilast |
| EP3029031A4 (en) | 2013-07-30 | 2017-01-11 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
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| AR094537A1 (es) | 2013-11-07 | 2015-08-12 | Bristol Myers Squibb Co | COMPUESTOS DE PIRIDILO SUSTITUIDOS CON ALQUILAMIDA ÚTILES COMO MODULADORES DE LAS RESPUESTAS DE IL-12, IL-23 Y/O IFNa |
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Cited By (1)
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|---|---|---|---|---|
| JP7453251B2 (ja) | 2019-04-30 | 2024-03-19 | セルジーン コーポレイション | アプレミラストおよびｔｙｋ２阻害剤を含む併用療法 |
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| CL2021002847A1 (es) | 2022-07-22 |
| CA3138473A1 (en) | 2020-11-05 |
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| WO2020222773A1 (en) | 2020-11-05 |
| KR20220002488A (ko) | 2022-01-06 |
| BR112021021809A2 (pt) | 2022-01-04 |
| BR112021021826A2 (pt) | 2022-01-04 |
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| BR112021021826A8 (pt) | 2022-06-21 |
| WO2020223431A1 (en) | 2020-11-05 |
| CO2021015614A2 (es) | 2021-12-10 |
| SG11202112043PA (en) | 2021-11-29 |
| JP2022537878A (ja) | 2022-08-31 |
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