JP2022537562A5 - - Google Patents

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Publication number
JP2022537562A5
JP2022537562A5 JP2021575438A JP2021575438A JP2022537562A5 JP 2022537562 A5 JP2022537562 A5 JP 2022537562A5 JP 2021575438 A JP2021575438 A JP 2021575438A JP 2021575438 A JP2021575438 A JP 2021575438A JP 2022537562 A5 JP2022537562 A5 JP 2022537562A5
Authority
JP
Japan
Prior art keywords
rna
construct
fragment
variant
nucleotide sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021575438A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022537562A (ja
Filing date
Publication date
Priority claimed from GBGB1908729.5A external-priority patent/GB201908729D0/en
Application filed filed Critical
Publication of JP2022537562A publication Critical patent/JP2022537562A/ja
Publication of JP2022537562A5 publication Critical patent/JP2022537562A5/ja
Priority to JP2025081437A priority Critical patent/JP2025118871A/ja
Pending legal-status Critical Current

Links

JP2021575438A 2019-06-18 2020-06-18 Rna構築物 Pending JP2022537562A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025081437A JP2025118871A (ja) 2019-06-18 2025-05-14 Rna構築物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1908729.5A GB201908729D0 (en) 2019-06-18 2019-06-18 RNA construct
GB1908729.5 2019-06-18
PCT/GB2020/051465 WO2020254804A1 (en) 2019-06-18 2020-06-18 Rna construct

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025081437A Division JP2025118871A (ja) 2019-06-18 2025-05-14 Rna構築物

Publications (2)

Publication Number Publication Date
JP2022537562A JP2022537562A (ja) 2022-08-26
JP2022537562A5 true JP2022537562A5 (https=) 2023-06-22

Family

ID=67432317

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021575438A Pending JP2022537562A (ja) 2019-06-18 2020-06-18 Rna構築物
JP2025081437A Pending JP2025118871A (ja) 2019-06-18 2025-05-14 Rna構築物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025081437A Pending JP2025118871A (ja) 2019-06-18 2025-05-14 Rna構築物

Country Status (12)

Country Link
US (1) US12569548B2 (https=)
EP (1) EP3987042A1 (https=)
JP (2) JP2022537562A (https=)
KR (1) KR20220038669A (https=)
CN (1) CN114402078B (https=)
AU (1) AU2020296337B2 (https=)
BR (1) BR112021024786A2 (https=)
CA (1) CA3143117A1 (https=)
GB (1) GB201908729D0 (https=)
IL (1) IL288956A (https=)
MX (1) MX2021015753A (https=)
WO (1) WO2020254804A1 (https=)

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CN110168093B (zh) * 2017-09-12 2023-08-15 中科蓝华(广州)生物医药技术有限公司 一种转染细胞内寄生虫的试剂盒及其应用
US11679163B2 (en) 2019-09-20 2023-06-20 Hdt Bio Corp. Compositions and methods for delivery of RNA
US20210369759A1 (en) * 2020-01-29 2021-12-02 Helix Nanotechnologies, Inc. METHODS AND COMPOSITIONS FOR NUCLEIC ACID EXPRESSION INVOLVING INHIBITION of NF-kB PATHWAYS AND/OR IRF PATHWAYS
AU2021236068A1 (en) 2020-03-09 2022-10-06 Arcturus Therapeutics, Inc. Compositions and methods for inducing immune responses
KR20220156933A (ko) 2020-03-23 2022-11-28 에이치디티 바이오 코포레이션 Rna의 전달을 위한 조성물 및 방법
EP4196128A4 (en) 2020-08-14 2024-06-12 Arcturus Therapeutics, Inc. METHOD FOR FREEZE DILIZATION OF LIPID NANOPARTICLES
GB202020061D0 (en) * 2020-12-17 2021-02-03 Imp College Innovations Ltd RNA construct
EP4267593A2 (en) 2020-12-23 2023-11-01 GlaxoSmithKline Biologicals SA Self-amplifying messenger rna
US20240240201A1 (en) 2021-05-04 2024-07-18 Mogrify Limited Cell conversion
CN113249408B (zh) * 2021-06-23 2021-11-02 深圳湾实验室 一种靶向激活体液免疫和细胞免疫的核酸疫苗载体构建及应用
JP2024535354A (ja) 2021-09-22 2024-09-30 エイチディーティー バイオ コーポレーション がん治療組成物およびその使用
CA3232719A1 (en) 2021-09-22 2023-03-30 Steven Gregory REED Sars-cov-2 rna vaccine compositions and methods of use
WO2023048760A1 (en) 2021-09-22 2023-03-30 Hdt Bio Corp. Rna vaccines against infectious diseases
EP4404919A4 (en) 2021-09-22 2025-08-20 Hdt Bio Corp DRIED NANOPARTICLE COMPOSITIONS
CN118715325A (zh) * 2021-12-17 2024-09-27 帝国理工创新有限公司 Rna构建体
GB202203060D0 (en) 2022-03-04 2022-04-20 Imperial College Innovations Ltd RNA molecule
CN119563028A (zh) * 2022-05-12 2025-03-04 尚威天成信使核糖核酸治疗公司 具有分泌抗原和免疫调节物的合成自扩增mRNA分子
CN115820696A (zh) * 2022-07-28 2023-03-21 怡道生物科技(苏州)有限公司 治疗性多价HPV mRNA疫苗及其制备方法
KR20240133629A (ko) * 2023-02-27 2024-09-04 주식회사 마이크로유니 자가 증폭 rna 컨스트럭트 및 이의 용도
WO2025008641A2 (en) 2023-07-06 2025-01-09 Imperial College Innovations Limited Rna molecule
CN121586776A (zh) * 2023-07-19 2026-02-27 上海复诺健生物科技有限公司 自扩增核酸分子及其应用
GB202313445D0 (en) 2023-09-04 2023-10-18 Imperial College Innovations Ltd Rna molecule
WO2025217136A2 (en) * 2024-04-08 2025-10-16 Amplitude Therapeutics, Inc. Trans-amplifying rnas encoding immunomodulators

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110117124A1 (en) 2007-08-31 2011-05-19 Sadoff Jerald C Enhancement of transgene expression from viral-based vaccine vectors by expression of suppressors of the type i interferon response
US7608256B2 (en) 2007-09-12 2009-10-27 Aeras Global Tb Vaccine Foundation Methods to increase transgene expression from bacterial-based delivery systems by co-expressing suppressors of the eukaryotic type I interferon response
US20140037680A1 (en) * 2012-08-06 2014-02-06 Glaxosmithkline Biologicals, S.A. Novel method
TR201809547T4 (tr) * 2012-11-09 2018-07-23 Biontech Rna Pharmaceuticals Gmbh Hücresel RNA ifadesine yönelik yöntem.
GB2592821B (en) * 2015-07-31 2022-01-12 Univ Minnesota Modified cells and methods of therapy
CA3045650A1 (en) * 2016-12-05 2018-06-14 Janssen Pharmaceuticals, Inc. Compositions and methods for enhancing gene expression

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