JP2022537521A5 - - Google Patents
Info
- Publication number
- JP2022537521A5 JP2022537521A5 JP2021573829A JP2021573829A JP2022537521A5 JP 2022537521 A5 JP2022537521 A5 JP 2022537521A5 JP 2021573829 A JP2021573829 A JP 2021573829A JP 2021573829 A JP2021573829 A JP 2021573829A JP 2022537521 A5 JP2022537521 A5 JP 2022537521A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- bispecific compound
- pharmaceutically acceptable
- compound according
- stereoisomer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962862879P | 2019-06-18 | 2019-06-18 | |
| US62/862,879 | 2019-06-18 | ||
| PCT/US2020/038130 WO2020257278A2 (en) | 2019-06-18 | 2020-06-17 | Small molecule target bromo/acetyl proteins and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022537521A JP2022537521A (ja) | 2022-08-26 |
| JP2022537521A5 true JP2022537521A5 (enExample) | 2023-06-26 |
| JP7626721B2 JP7626721B2 (ja) | 2025-02-04 |
Family
ID=74037322
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021573829A Active JP7626721B2 (ja) | 2019-06-18 | 2020-06-17 | 小分子標的ブロモ／アセチルタンパク質およびその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US12496348B2 (enExample) |
| EP (1) | EP3986470A4 (enExample) |
| JP (1) | JP7626721B2 (enExample) |
| CN (1) | CN114007652A (enExample) |
| AU (1) | AU2020295399B2 (enExample) |
| CA (1) | CA3143507A1 (enExample) |
| WO (1) | WO2020257278A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112969696B (zh) * | 2018-11-02 | 2024-06-11 | 达纳-法伯癌症研究公司 | 乙酰化书写器抑制剂的开发及其用途 |
| AU2022207648A1 (en) | 2021-01-13 | 2023-07-27 | Monte Rosa Therapeutics Ag | Isoindolinone compounds |
| CN114989158A (zh) * | 2021-03-02 | 2022-09-02 | 复旦大学 | 组蛋白乙酰转移酶p300溴结构域抑制剂及其药用组合物及其应用 |
| WO2022257894A1 (zh) * | 2021-06-07 | 2022-12-15 | 贝达药业股份有限公司 | P300抑制剂及其在医药上的应用 |
| CN118359600A (zh) * | 2023-01-17 | 2024-07-19 | 中国科学院广州生物医药与健康研究院 | 一种芳基咪唑基异恶唑类化合物及其制备方法和应用 |
| CN121005703A (zh) * | 2024-05-24 | 2025-11-25 | 中国科学院广州生物医药与健康研究院 | 一种酰胺吲嗪类化合物及其制备方法和应用 |
| CN119707936B (zh) * | 2025-02-25 | 2025-07-25 | 中南大学 | 一种2,4-二取代-5-氟嘧啶衍生物的盐的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2016004570A (es) | 2013-10-11 | 2016-09-08 | Genentech Inc | Uso de inhibidores del bromodominio de cbp/ep300 para la inmunoterapia del cáncer. |
| JP6820254B2 (ja) | 2014-10-10 | 2021-01-27 | ジェネンテック， インコーポレイテッド | 治療用化合物およびその使用 |
| WO2016105518A1 (en) | 2014-12-23 | 2016-06-30 | Dana-Farber Cancer Institute, Inc. | Methods to induce targeted protein degradation through bifunctional molecules |
| US9694084B2 (en) | 2014-12-23 | 2017-07-04 | Dana-Farber Cancer Institute, Inc. | Methods to induce targeted protein degradation through bifunctional molecules |
| GB201506658D0 (en) | 2015-04-20 | 2015-06-03 | Cellcentric Ltd | Pharmaceutical compounds |
| CN109641874A (zh) * | 2016-05-10 | 2019-04-16 | C4医药公司 | 用于靶蛋白降解的c3-碳连接的戊二酰亚胺降解决定子体 |
| CN110769822A (zh) * | 2017-06-20 | 2020-02-07 | C4医药公司 | 用于蛋白降解的n/o-连接的降解决定子和降解决定子体 |
| WO2019060742A1 (en) | 2017-09-22 | 2019-03-28 | Kymera Therapeutics, Inc | AGENTS FOR DEGRADING PROTEINS AND USES THEREOF |
| CN112969696B (zh) | 2018-11-02 | 2024-06-11 | 达纳-法伯癌症研究公司 | 乙酰化书写器抑制剂的开发及其用途 |
-
2020
- 2020-06-17 WO PCT/US2020/038130 patent/WO2020257278A2/en not_active Ceased
- 2020-06-17 CA CA3143507A patent/CA3143507A1/en active Pending
- 2020-06-17 JP JP2021573829A patent/JP7626721B2/ja active Active
- 2020-06-17 EP EP20825420.1A patent/EP3986470A4/en active Pending
- 2020-06-17 CN CN202080044388.9A patent/CN114007652A/zh active Pending
- 2020-06-17 AU AU2020295399A patent/AU2020295399B2/en active Active
- 2020-06-17 US US17/617,226 patent/US12496348B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022537521A5 (enExample) | ||
| IL278297B2 (en) | Substituted heterocyclic inhibitors of ptpn11 | |
| JP2021511342A5 (enExample) | ||
| ES2750309T3 (es) | Nuevos derivados de arilamida que tienen propiedades antiandrogénicas | |
| JP2018502902A5 (enExample) | ||
| JP2009536620A5 (enExample) | ||
| JP2017528498A5 (enExample) | ||
| US12187720B2 (en) | Compounds for treatment of cancer | |
| CA2448356A1 (en) | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | |
| CN109843872A (zh) | 作为ido抑制剂和/或ido-hdac双重抑制剂的多环化合物 | |
| JP2023538524A5 (enExample) | ||
| JP2007505044A5 (enExample) | ||
| JP2023513793A5 (enExample) | ||
| EP0676201B1 (en) | Use of a riminophenazine for treating MDR resistance | |
| CN116113416A (zh) | 四环类衍生物、其制备方法和其医药上的用途 | |
| JP2015512430A (ja) | 癌を治療するための官能性チエノ−インドール誘導体 | |
| TW201641492A (zh) | 經取代1,2,3-三唑、其用途、以及包含其之醫藥組成物 | |
| JPH01128962A (ja) | 抗新生物剤としてのポリアミン誘導体類 | |
| JPWO2019031614A5 (enExample) | ||
| JP2022502378A5 (enExample) | ||
| CA2504496A1 (en) | N-oxides and derivatives of melphalan for treating diseased states associated with hypoxia inducible factor | |
| JP2005531563A5 (enExample) | ||
| RU2004111787A (ru) | Ретиноидные агонисты (1), производные алкилмочевины | |
| JP2022521474A5 (enExample) | ||
| CN108473449B (zh) | 一种作为吲哚胺-2,3-双加氧酶抑制剂的砜脒及其制备方法和用途 |