JP2022536088A - 抗ｉｌ２３特異的抗体で乾癬性関節炎を治療する安全かつ有効な方法 - Google Patents

抗ｉｌ２３特異的抗体で乾癬性関節炎を治療する安全かつ有効な方法 Download PDF

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JP2022536088A
JP2022536088A JP2021571955A JP2021571955A JP2022536088A JP 2022536088 A JP2022536088 A JP 2022536088A JP 2021571955 A JP2021571955 A JP 2021571955A JP 2021571955 A JP2021571955 A JP 2021571955A JP 2022536088 A JP2022536088 A JP 2022536088A
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antibody
guselkumab
week
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treatment
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JP2022536088A5 (https=
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シャー，エリザベス
コルマイアー，アレクサ
シュ，シエ
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ヤンセン バイオテツク，インコーポレーテツド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
JP2021571955A 2019-06-04 2020-06-04 抗ｉｌ２３特異的抗体で乾癬性関節炎を治療する安全かつ有効な方法 Pending JP2022536088A (ja)

Priority Applications (1)

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JP2025093642A JP2025143278A (ja) 2019-06-04 2025-06-04 抗ｉｌ２３特異的抗体で乾癬性関節炎を治療する安全かつ有効な方法

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US201962856997P 2019-06-04 2019-06-04
US62/856,997 2019-06-04
US202062993259P 2020-03-23 2020-03-23
US62/993,259 2020-03-23
PCT/IB2020/055278 WO2020245766A1 (en) 2019-06-04 2020-06-04 Safe and effective method of treating psoriatic arthritis with anti-il23 specific antibody

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JP2025093642A Division JP2025143278A (ja) 2019-06-04 2025-06-04 抗ｉｌ２３特異的抗体で乾癬性関節炎を治療する安全かつ有効な方法

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JP2022536088A true JP2022536088A (ja) 2022-08-12
JP2022536088A5 JP2022536088A5 (https=) 2023-05-30

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JP2021571955A Pending JP2022536088A (ja) 2019-06-04 2020-06-04 抗ｉｌ２３特異的抗体で乾癬性関節炎を治療する安全かつ有効な方法
JP2025093642A Pending JP2025143278A (ja) 2019-06-04 2025-06-04 抗ｉｌ２３特異的抗体で乾癬性関節炎を治療する安全かつ有効な方法

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US (2) US20200385453A1 (https=)
EP (1) EP3980065A4 (https=)
JP (2) JP2022536088A (https=)
KR (1) KR20220016954A (https=)
CN (1) CN114025796A (https=)
AU (1) AU2020288749A1 (https=)
BR (1) BR112021024349A2 (https=)
CA (1) CA3142667A1 (https=)
IL (1) IL288496A (https=)
MA (1) MA56124A (https=)
MX (1) MX2021014953A (https=)
WO (1) WO2020245766A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4305062A1 (en) * 2021-03-12 2024-01-17 Janssen Biotech, Inc. Method of treating psoriatic arthritis patients with inadequate response to tnf therapy with anti-il23 specific antibody
IL305802A (en) * 2021-03-12 2023-11-01 Janssen Biotech Inc A safe and effective method for the treatment of rheumatoid arthritis with a specific anti-IL23 antibody
JP2024536932A (ja) * 2021-10-11 2024-10-08 ワイ－トラップ， インコーポレイテッド Ｉｌ－２３シグナル伝達を阻害する組成物および方法
EP4526342A1 (en) * 2022-05-18 2025-03-26 Janssen Biotech, Inc. Method for evaluating and treating psoriatic arthritis with il23 antibody

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018140121A1 (en) * 2017-01-30 2018-08-02 Janssen Biotech, Inc. Anti-tnf antibodies, compositions, and methods for the treatment of active psoriatic arthritis
JP2019511532A (ja) * 2016-04-15 2019-04-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 炎症性疾患の処置法
WO2019090329A1 (en) * 2017-11-06 2019-05-09 Janssen Biotech, Inc. Safe and effective method of treating psoriatic arthritis with anti-il23 specific antibody

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