JP2022534778A5 - - Google Patents
Info
- Publication number
- JP2022534778A5 JP2022534778A5 JP2021571518A JP2021571518A JP2022534778A5 JP 2022534778 A5 JP2022534778 A5 JP 2022534778A5 JP 2021571518 A JP2021571518 A JP 2021571518A JP 2021571518 A JP2021571518 A JP 2021571518A JP 2022534778 A5 JP2022534778 A5 JP 2022534778A5
- Authority
- JP
- Japan
- Prior art keywords
- patient
- cells
- derived
- microorganospheres
- tissue sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962853219P | 2019-05-28 | 2019-05-28 | |
| US62/853,219 | 2019-05-28 | ||
| PCT/US2020/026275 WO2020242594A1 (en) | 2019-05-28 | 2020-04-01 | Methods and apparatuses for patient-derived micro-organospheres |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022534778A JP2022534778A (ja) | 2022-08-03 |
| JP2022534778A5 true JP2022534778A5 (enExample) | 2023-04-07 |
Family
ID=73549270
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021571518A Pending JP2022534778A (ja) | 2019-05-28 | 2020-04-01 | 患者由来ミクロオルガノスフェアのための方法及び装置 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11555180B2 (enExample) |
| EP (1) | EP3976064A4 (enExample) |
| JP (1) | JP2022534778A (enExample) |
| CN (1) | CN116157134A (enExample) |
| AU (1) | AU2020283390A1 (enExample) |
| CA (1) | CA3142113A1 (enExample) |
| IL (1) | IL288370A (enExample) |
| MX (1) | MX2021014439A (enExample) |
| SG (1) | SG11202113122SA (enExample) |
| WO (1) | WO2020242594A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114410466A (zh) * | 2020-04-01 | 2022-04-29 | 沈西凌 | 用于个性化癌症治疗的精确药物筛选 |
| WO2022115455A1 (en) * | 2020-11-24 | 2022-06-02 | Duke University | Droplet organoid-based immuno-oncology assays and methods of using same |
| DE102022100146B4 (de) | 2022-01-04 | 2023-11-30 | Precomb Therapeutics Ag | Verfahren zur analyse von personalisierten anti-krebs-wirkstoffen in zellkulturen |
| JP2025514291A (ja) * | 2022-04-29 | 2025-05-02 | ザイリス, インク. | マイクロオルガノスフェアを使用して肝細胞毒性を試験するための方法及び装置 |
| EP4519686A4 (en) * | 2022-05-03 | 2026-05-06 | Xilis Inc | Patient-Derived Microorganospheres (MOS) Enabling Clinical Precision Oncology |
| WO2024039770A2 (en) * | 2022-08-17 | 2024-02-22 | Xilis, Inc. | Imaging-based microorganosphere drug assays |
| JP2025532497A (ja) * | 2022-09-07 | 2025-10-01 | ザイリス, インク. | 多発性骨髄腫MicroOrganoSphere |
| EP4601758A1 (en) | 2022-10-11 | 2025-08-20 | Xilis, Inc. | Integrated microfluidic system for generation of microorganospheres (mos) |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5266480A (en) | 1986-04-18 | 1993-11-30 | Advanced Tissue Sciences, Inc. | Three-dimensional skin culture system |
| PT671923E (pt) | 1992-10-09 | 2001-10-30 | Advanced Tissue Sciences Inc | Celulas de reserva do figado |
| WO2005047863A2 (en) | 2003-11-10 | 2005-05-26 | Platypus Technologies, Llc | Substrates, devices, and methods for cellular assays |
| US7759111B2 (en) * | 2004-08-27 | 2010-07-20 | The Regents Of The University Of California | Cell encapsulation microfluidic device |
| WO2006078814A2 (en) | 2005-01-20 | 2006-07-27 | The Regents Of The University Of California | Cellular microarrays for screening differentiation factors |
| US20070134209A1 (en) * | 2005-12-12 | 2007-06-14 | Metafluidics, Inc. | Cellular encapsulation for self-assembly of engineered tissue |
| US20120135875A1 (en) * | 2008-02-29 | 2012-05-31 | Bristol-Myers Squibb Company | Methods for determining sensitivity to vascular endothelial growth factor receptor-2 modulators |
| CN103635587A (zh) | 2008-04-08 | 2014-03-12 | 麻省理工学院 | 三维微流平台和其使用方法 |
| WO2012018982A2 (en) * | 2010-08-05 | 2012-02-09 | Tufts Medical Center, Inc. | Methods and kits for modulating tumor invasiveness and metastatic potential |
| GB201105226D0 (en) * | 2011-03-29 | 2011-05-11 | Univ Leiden | Methods |
| SG10201805199RA (en) * | 2011-06-02 | 2018-07-30 | Harvard College | Methods and Uses for Ex Vivo Tissue Culture Systems |
| US9334473B2 (en) | 2012-08-17 | 2016-05-10 | Jelena Vukasinovic | Three dimensional cell culture compositions and methods of use |
| WO2014082096A1 (en) * | 2012-11-26 | 2014-05-30 | The Trustees Of Columbia University In The City Of New York | Method for culture of human and mouse prostate organoids and uses thereof |
| KR102257305B1 (ko) | 2013-03-28 | 2021-05-28 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 미세유동 장치 및 분비물의 다세포 검정법에서의 그의 사용 방법 |
| AU2014275006A1 (en) * | 2013-06-04 | 2015-12-24 | University Of Miami | Assays, methods and kits for analyzing sensitivity and resistance to anti-cancer drugs, predicting a cancer patient's prognosis, and personalized treatment strategies |
| WO2015027086A1 (en) | 2013-08-21 | 2015-02-26 | University Of Louisville Research Foundation, Inc. | Methods of making spheroids including biologically-relevant materials |
| US10928382B2 (en) * | 2014-06-26 | 2021-02-23 | Northeastern University | Microfluidic device and method for analysis of tumor cell microenvironments |
| EP3242930A4 (en) | 2015-01-07 | 2019-01-16 | Dana-Farber Cancer Institute, Inc. | MICROFLUIDIC CELL CULTURE OF TUMOR CELL SPHEROIDS FROM PATIENTS |
| WO2016145242A1 (en) * | 2015-03-11 | 2016-09-15 | Agenus Inc. | Methods and compositions for high throughput screening of biomolecules using gel microdrops |
| AU2016346332B2 (en) * | 2015-10-26 | 2022-03-03 | University Of Wyoming | Methods of generating microparticles and porous hydrogels using microfluidics |
| TWM516858U (zh) | 2015-11-19 | 2016-02-11 | 金鼎聯合科技纖維股份有限公司 | 膠線改良結構 |
| GB2564582B (en) | 2016-02-01 | 2021-09-22 | Emulate Inc | Systems and methods for growth of intestinal cells in microfluidic devices |
| JP6967535B2 (ja) * | 2016-06-15 | 2021-11-17 | ミメタス ビー.ブイ. | 細胞培養装置及び方法 |
| EP3484487A4 (en) * | 2016-07-12 | 2020-06-17 | The University of North Carolina at Chapel Hill | BIOMATRIX SCALES FOR USE IN THE DIAGNOSIS AND MODELING OF CANCER |
| US11180735B2 (en) * | 2016-10-28 | 2021-11-23 | The Board Of Trustees Of The Leland Stanford Junior University | Methods to preserve tumor-stromal interactions in culture and therapeutic predictive applications thereof |
| CN110997900B (zh) * | 2017-07-14 | 2024-06-14 | 多伦多大学管理委员会 | 用于快速产生用于化合物筛选的类器官/球状体的微流体平台 |
| WO2019067795A1 (en) | 2017-09-27 | 2019-04-04 | Duke University | PATIENT-SPECIFIC CLINICAL TRIALS AND METHODS OF TREATMENT THEREOF |
| US11166920B2 (en) * | 2017-10-05 | 2021-11-09 | Auburn University | Microfluidics device for fabrication of large, uniform, injectable hydrogel microparticles for cell encapsulation |
| WO2019111998A1 (ja) * | 2017-12-08 | 2019-06-13 | 京ダイアグノスティクス株式会社 | 癌スフェロイドの製造方法および大腸癌患者の選択方法 |
| GB201721615D0 (en) * | 2017-12-21 | 2018-02-07 | Koninklijke Nederlandse Akademie Van Wetenschappen | Immune cell organoid co-cultures |
| CN110004111B (zh) * | 2019-04-22 | 2021-10-08 | 清华-伯克利深圳学院筹备办公室 | 一种类器官球体的制备方法 |
-
2020
- 2020-04-01 AU AU2020283390A patent/AU2020283390A1/en active Pending
- 2020-04-01 CN CN202080006103.2A patent/CN116157134A/zh active Pending
- 2020-04-01 WO PCT/US2020/026275 patent/WO2020242594A1/en not_active Ceased
- 2020-04-01 MX MX2021014439A patent/MX2021014439A/es unknown
- 2020-04-01 EP EP20812521.1A patent/EP3976064A4/en active Pending
- 2020-04-01 US US16/838,010 patent/US11555180B2/en active Active
- 2020-04-01 JP JP2021571518A patent/JP2022534778A/ja active Pending
- 2020-04-01 SG SG11202113122SA patent/SG11202113122SA/en unknown
- 2020-04-01 CA CA3142113A patent/CA3142113A1/en active Pending
-
2021
- 2021-11-24 IL IL288370A patent/IL288370A/en unknown
-
2022
- 2022-07-26 US US17/874,136 patent/US20230002737A1/en active Pending
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