JP2022534245A5 - - Google Patents
Info
- Publication number
- JP2022534245A5 JP2022534245A5 JP2021570258A JP2021570258A JP2022534245A5 JP 2022534245 A5 JP2022534245 A5 JP 2022534245A5 JP 2021570258 A JP2021570258 A JP 2021570258A JP 2021570258 A JP2021570258 A JP 2021570258A JP 2022534245 A5 JP2022534245 A5 JP 2022534245A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- formula
- independently
- polymer
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962853658P | 2019-05-28 | 2019-05-28 | |
| US62/853,658 | 2019-05-28 | ||
| US201962907458P | 2019-09-27 | 2019-09-27 | |
| US62/907,458 | 2019-09-27 | ||
| PCT/US2020/035007 WO2020243370A1 (en) | 2019-05-28 | 2020-05-28 | Polymer comprising multiple functionalized sidechains for biomolecule delivery |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022534245A JP2022534245A (ja) | 2022-07-28 |
| JP2022534245A5 true JP2022534245A5 (enExample) | 2023-06-05 |
| JP7805789B2 JP7805789B2 (ja) | 2026-01-26 |
Family
ID=71094892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021570258A Active JP7805789B2 (ja) | 2019-05-28 | 2020-05-28 | 生体分子送達のための複数の機能化側鎖を含むポリマー |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220340712A1 (enExample) |
| EP (1) | EP3976015A1 (enExample) |
| JP (1) | JP7805789B2 (enExample) |
| KR (1) | KR20220013570A (enExample) |
| AU (1) | AU2020282798A1 (enExample) |
| CA (1) | CA3142035A1 (enExample) |
| WO (1) | WO2020243370A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7568511B2 (ja) | 2018-04-27 | 2024-10-16 | ジーンエディット インコーポレイテッド | カチオン性ポリマーおよびその生体分子送達のための使用 |
| JP2022502384A (ja) | 2018-09-25 | 2022-01-11 | 国立大学法人 東京大学 | 両親媒性ポリアミノ酸、該両親媒性ポリアミノ酸を用いたブロックコポリマー、および該両親媒性ポリアミノ酸または該ブロックコポリマーと核酸とを含む複合体 |
| EP4352131A1 (en) | 2021-06-11 | 2024-04-17 | Genedit Inc. | Biodegradable polymer comprising side chains with polyamine and polyalkylene oxide groups |
| WO2024020332A1 (en) * | 2022-07-18 | 2024-01-25 | Bridgeway Innovations, Llc | Oxidatively degrading and ros scavenging polymers for medical applications |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9811059D0 (en) * | 1998-05-23 | 1998-07-22 | Univ Strathclyde | Polyamino acid vesicles |
| IL131074A0 (en) * | 1999-07-23 | 2001-03-19 | Polygene Ltd | A biodegradable polycation composition for delivery of an anionic macromolecule |
| WO2010075303A1 (en) | 2008-12-23 | 2010-07-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Splicing factors with a puf protein rna-binding domain and a splicing effector domain and uses of same |
| WO2010093036A1 (ja) * | 2009-02-13 | 2010-08-19 | 国立大学法人東京大学 | カチオン性のポリ（アミノ酸）およびその使用 |
| EP2462938B1 (en) * | 2009-07-23 | 2018-08-29 | The University of Tokyo | Anionic polymer, polyion complex and ternary polymer composite using anionic polymer, and pharmaceutical composition |
| JP4655298B1 (ja) * | 2010-02-23 | 2011-03-23 | ナノキャリア株式会社 | 短鎖のカチオン性ポリアミノ酸およびその使用 |
| US9580714B2 (en) | 2010-11-24 | 2017-02-28 | The University Of Western Australia | Peptides for the specific binding of RNA targets |
| US20120237565A1 (en) * | 2011-03-14 | 2012-09-20 | Intezyne Technologies, Incorporated | Pegylated polyplexes containing two or more different polymers for polynucleotide delivery |
| CA2873073A1 (en) | 2012-04-16 | 2013-10-24 | The University Of Western Australia | Peptides for the binding of nucleotide targets |
| US20140310830A1 (en) | 2012-12-12 | 2014-10-16 | Feng Zhang | CRISPR-Cas Nickase Systems, Methods And Compositions For Sequence Manipulation in Eukaryotes |
| ES2576126T3 (es) | 2012-12-12 | 2016-07-05 | The Broad Institute, Inc. | Modificación por tecnología genética y optimización de sistemas, métodos y composiciones enzimáticas mejorados para la manipulación de secuencias |
| CN114634950A (zh) | 2012-12-12 | 2022-06-17 | 布罗德研究所有限公司 | 用于序列操纵的crispr-cas组分系统、方法以及组合物 |
| EP2931898B1 (en) | 2012-12-12 | 2016-03-09 | The Broad Institute, Inc. | Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains |
| JP2016504026A (ja) | 2012-12-12 | 2016-02-12 | ザ・ブロード・インスティテュート・インコーポレイテッド | 配列操作のための系、方法および最適化ガイド組成物のエンジニアリング |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
| US20180237800A1 (en) * | 2015-09-21 | 2018-08-23 | The Regents Of The University Of California | Compositions and methods for target nucleic acid modification |
| EP3355936A4 (en) * | 2015-09-30 | 2019-06-12 | Ramot at Tel-Aviv University Ltd. | COMPOUNDS WITH POLYAMINATED POLYGLUTAMINIC ACID AND USES THEREOF FOR THE RELEASE OF OLIGONUCLEOTIDES |
| EP3541945A4 (en) * | 2016-11-18 | 2020-12-09 | Genedit Inc. | COMPOSITIONS AND METHODS OF MODIFICATION OF TARGET NUCLEIC ACIDS |
| WO2021217082A1 (en) * | 2020-04-23 | 2021-10-28 | Genedit Inc. | Polymer with cationic and hydrophobic side chains |
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2020
- 2020-05-28 JP JP2021570258A patent/JP7805789B2/ja active Active
- 2020-05-28 US US17/614,307 patent/US20220340712A1/en active Pending
- 2020-05-28 KR KR1020217042746A patent/KR20220013570A/ko not_active Ceased
- 2020-05-28 CA CA3142035A patent/CA3142035A1/en active Pending
- 2020-05-28 EP EP20733170.3A patent/EP3976015A1/en active Pending
- 2020-05-28 AU AU2020282798A patent/AU2020282798A1/en active Pending
- 2020-05-28 WO PCT/US2020/035007 patent/WO2020243370A1/en not_active Ceased