JP2022533009A5 - - Google Patents

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Publication number
JP2022533009A5
JP2022533009A5 JP2021564299A JP2021564299A JP2022533009A5 JP 2022533009 A5 JP2022533009 A5 JP 2022533009A5 JP 2021564299 A JP2021564299 A JP 2021564299A JP 2021564299 A JP2021564299 A JP 2021564299A JP 2022533009 A5 JP2022533009 A5 JP 2022533009A5
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JP
Japan
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composition according
seq
immune complex
amino acid
acid sequence
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JP2021564299A
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English (en)
Japanese (ja)
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JP7585231B2 (ja
JP2022533009A (ja
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Priority claimed from PCT/US2020/030478 external-priority patent/WO2020223351A1/en
Publication of JP2022533009A publication Critical patent/JP2022533009A/ja
Publication of JP2022533009A5 publication Critical patent/JP2022533009A5/ja
Priority to JP2024193438A priority Critical patent/JP2025023995A/ja
Application granted granted Critical
Publication of JP7585231B2 publication Critical patent/JP7585231B2/ja
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JP2021564299A 2019-04-29 2020-04-29 抗cd123免疫複合体を含む治療的組み合わせ Active JP7585231B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024193438A JP2025023995A (ja) 2019-04-29 2024-11-05 抗cd123免疫複合体を含む治療的組み合わせ

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962839974P 2019-04-29 2019-04-29
US62/839,974 2019-04-29
US201962860598P 2019-06-12 2019-06-12
US62/860,598 2019-06-12
PCT/US2020/030478 WO2020223351A1 (en) 2019-04-29 2020-04-29 Therapeutic combinations comprising anti-cd123 immunoconjugates

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024193438A Division JP2025023995A (ja) 2019-04-29 2024-11-05 抗cd123免疫複合体を含む治療的組み合わせ

Publications (3)

Publication Number Publication Date
JP2022533009A JP2022533009A (ja) 2022-07-21
JP2022533009A5 true JP2022533009A5 (enExample) 2023-04-13
JP7585231B2 JP7585231B2 (ja) 2024-11-18

Family

ID=73029177

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021564299A Active JP7585231B2 (ja) 2019-04-29 2020-04-29 抗cd123免疫複合体を含む治療的組み合わせ
JP2024193438A Pending JP2025023995A (ja) 2019-04-29 2024-11-05 抗cd123免疫複合体を含む治療的組み合わせ

Family Applications After (1)

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JP2024193438A Pending JP2025023995A (ja) 2019-04-29 2024-11-05 抗cd123免疫複合体を含む治療的組み合わせ

Country Status (12)

Country Link
US (2) US11701428B2 (enExample)
EP (1) EP3962528A4 (enExample)
JP (2) JP7585231B2 (enExample)
KR (1) KR20220004669A (enExample)
CN (1) CN113853217A (enExample)
AU (1) AU2020265225A1 (enExample)
CA (1) CA3137454A1 (enExample)
IL (1) IL287446A (enExample)
MA (1) MA55816A (enExample)
SG (1) SG11202110702WA (enExample)
TW (1) TWI865521B (enExample)
WO (1) WO2020223351A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220004669A (ko) 2019-04-29 2022-01-11 이뮤노젠 아이엔씨 항-cd123 면역접합체를 포함하는 치료적 조합물
IL308321A (en) * 2021-05-11 2024-01-01 Abbvie Inc Venetoclax dosing regimens for use in treating myelodysplastic syndromes in combination with azacitidine
WO2024123765A1 (en) * 2022-12-08 2024-06-13 Immunogen, Inc. Therapeutic combinations comprising anti-cd123 antibody-drug conjugates and anti-cd47 antibodies
US20260083749A1 (en) * 2024-05-10 2026-03-26 Immunogen, Inc. Anti-cd123 immunoconjugates for the treatment of acute myeloid leukemia

Family Cites Families (22)

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Publication number Priority date Publication date Assignee Title
US8163279B2 (en) 2007-04-13 2012-04-24 Stemline Therapeutics, Inc. IL3Rα antibody conjugates and uses thereof
WO2009080831A1 (en) * 2007-12-26 2009-07-02 Biotest Ag Method of decreasing cytotoxic side-effects and improving efficacy of immunoconjugates
WO2012142411A1 (en) * 2011-04-15 2012-10-18 Clavis Pharma Asa Systems and methods for detecting hent1 expression in hematological disorders
TW201709932A (zh) 2015-06-12 2017-03-16 西雅圖遺傳學公司 Cd123抗體及其共軛物
SMT202000614T1 (it) 2015-06-29 2021-01-05 Immunogen Inc Coniugati di anticorpi ingegnerizzati con cisteina
AU2016285552B2 (en) 2015-06-29 2022-10-13 Immunogen, Inc. Anti-CD123 antibodies and conjugates and derivatives thereof
US10695352B2 (en) * 2015-10-15 2020-06-30 Celgene Corporation Combination therapy for treating malignancies
KR102124715B1 (ko) * 2015-11-03 2020-06-18 제넨테크, 인크. 암의 치료를 위한 bcl-2 억제제 및 mek 억제제의 조합물
US20170189548A1 (en) 2015-11-25 2017-07-06 Immunogen, Inc. Pharmaceutical formulations and methods of use thereof
WO2017160954A1 (en) 2016-03-15 2017-09-21 Seattle Genetics, Inc. Combinations of pbd-based antibody drug conjugates with bcl-2 inhibitors
EP3318276A1 (en) * 2016-11-04 2018-05-09 Janssen Biotech, Inc. Combinations of a telomerase inhibitor and a bcl-2 inhibitor for the treatment of hematological cancers
WO2018098258A2 (en) 2016-11-23 2018-05-31 Immunogen, Inc. Selective sulfonation of benzodiazepine derivatives
KR20200041834A (ko) * 2017-06-01 2020-04-22 젠코어 인코포레이티드 Cd123 및 cd3에 결합하는 이중특이성 항체
GB2567613A (en) * 2017-06-16 2019-04-24 Argenx Bvba Treatment for acute myeloid leukaemia
US20190062428A1 (en) * 2017-06-19 2019-02-28 Surface Oncology, Inc. Combination of anti-cd47 antibodies and cell death-inducing agents, and uses thereof
CA3069558A1 (en) 2017-07-09 2019-01-17 Biosight Ltd. Combination cancer therapy
JP2020528061A (ja) * 2017-07-26 2020-09-17 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト BET阻害剤、Bcl−2阻害剤及び抗CD20抗体を用いた併用療法
EP3684409A4 (en) * 2017-09-22 2021-06-23 Immunogen, Inc. SEPARATION OF TRIPLE LIGHT CHAIN ANTIBODIES USING CATION EXCHANGE CHROMATOGRAPHY
KR20200070254A (ko) * 2017-09-22 2020-06-17 이뮤노젠 아이엔씨 면역접합체에서 메티오닌 산화를 방지하는 방법
MA54088A (fr) * 2018-10-30 2022-03-16 Immunogen Inc Procédés de traitement faisant appel à des immunoconjugués anti-cd123
WO2020092344A1 (en) * 2018-10-31 2020-05-07 Health Research, Inc. Combination treatment with anti-cd123 antibody drug conjugate and parp inhibitor
KR20220004669A (ko) 2019-04-29 2022-01-11 이뮤노젠 아이엔씨 항-cd123 면역접합체를 포함하는 치료적 조합물

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