JP2022531892A5 - - Google Patents

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Publication number
JP2022531892A5
JP2022531892A5 JP2021566142A JP2021566142A JP2022531892A5 JP 2022531892 A5 JP2022531892 A5 JP 2022531892A5 JP 2021566142 A JP2021566142 A JP 2021566142A JP 2021566142 A JP2021566142 A JP 2021566142A JP 2022531892 A5 JP2022531892 A5 JP 2022531892A5
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JP
Japan
Prior art keywords
ligand
binding site
particle according
capsid protein
group
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JP2021566142A
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English (en)
Japanese (ja)
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JP2022531892A (ja
JP7737312B2 (ja
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Priority claimed from EP19173365.8A external-priority patent/EP3736330A1/en
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Publication of JP2022531892A5 publication Critical patent/JP2022531892A5/ja
Priority to JP2025077923A priority Critical patent/JP2025121993A/ja
Application granted granted Critical
Publication of JP7737312B2 publication Critical patent/JP7737312B2/ja
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JP2021566142A 2019-05-08 2020-05-07 遺伝子治療のための改変型アデノ随伴ウイルス （ａａｖ） 粒子 Active JP7737312B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025077923A JP2025121993A (ja) 2019-05-08 2025-05-08 遺伝子治療のための改変型アデノ随伴ウイルス （ａａｖ） 粒子

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19173365.8 2019-05-08
EP19173365.8A EP3736330A1 (en) 2019-05-08 2019-05-08 Modified adeno-associated virus (aav) particles for gene therapy
PCT/EP2020/062713 WO2020225363A2 (en) 2019-05-08 2020-05-07 Modified adeno-associated virus (aav) particles for gene therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025077923A Division JP2025121993A (ja) 2019-05-08 2025-05-08 遺伝子治療のための改変型アデノ随伴ウイルス （ａａｖ） 粒子

Publications (3)

Publication Number Publication Date
JP2022531892A JP2022531892A (ja) 2022-07-12
JP2022531892A5 true JP2022531892A5 (https=) 2023-05-15
JP7737312B2 JP7737312B2 (ja) 2025-09-10

Family

ID=66483846

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021566142A Active JP7737312B2 (ja) 2019-05-08 2020-05-07 遺伝子治療のための改変型アデノ随伴ウイルス （ａａｖ） 粒子
JP2025077923A Withdrawn JP2025121993A (ja) 2019-05-08 2025-05-08 遺伝子治療のための改変型アデノ随伴ウイルス （ａａｖ） 粒子

Family Applications After (1)

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JP2025077923A Withdrawn JP2025121993A (ja) 2019-05-08 2025-05-08 遺伝子治療のための改変型アデノ随伴ウイルス （ａａｖ） 粒子

Country Status (12)

Country Link
US (1) US20220288234A1 (https=)
EP (2) EP3736330A1 (https=)
JP (2) JP7737312B2 (https=)
KR (1) KR20220008863A (https=)
CN (1) CN114008194A (https=)
AU (1) AU2020268759A1 (https=)
BR (1) BR112021022385A2 (https=)
CA (1) CA3139183A1 (https=)
IL (1) IL287614A (https=)
MX (1) MX2021013619A (https=)
SG (1) SG11202112029XA (https=)
WO (1) WO2020225363A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021378075B2 (en) 2020-11-11 2025-03-27 Borea Therapeutics S.R.L. Modified viral particles for gene therapy
CN118109515A (zh) * 2022-11-29 2024-05-31 中国科学院深圳先进技术研究院 一种基于生物正交技术的病毒载体及其制备方法和应用
CN121889172A (zh) 2023-07-21 2026-04-17 意大利商博雷亚医疗有限责任公司 制备表面修饰病毒衣壳的方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797368A (en) 1985-03-15 1989-01-10 The United States Of America As Represented By The Department Of Health And Human Services Adeno-associated virus as eukaryotic expression vector
US5139941A (en) 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors
US5173414A (en) 1990-10-30 1992-12-22 Applied Immune Sciences, Inc. Production of recombinant adeno-associated virus vectors
US5252479A (en) 1991-11-08 1993-10-12 Research Corporation Technologies, Inc. Safe vector for gene therapy
US5756283A (en) 1995-06-05 1998-05-26 The Trustees Of The University Of Pennsylvania Method for improved production of recombinant adeno-associated viruses for gene therapy
EP1486567A1 (en) 2003-06-11 2004-12-15 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Improved adeno-associated virus (AAV) vector for gene therapy
BR112014029417B1 (pt) 2012-05-25 2023-03-07 Cellectis Método ex vivo para a preparação de células t para imunoterapia
EP3492597A3 (en) * 2013-05-21 2019-08-28 University of Florida Research Foundation, Inc. Capsid-modified, raav3 vector compositions and methods of use in gene therapy of human liver cancer
WO2014191128A1 (en) 2013-05-29 2014-12-04 Cellectis Methods for engineering t cells for immunotherapy by using rna-guided cas nuclease system
CN104592364B (zh) * 2013-10-30 2018-05-01 北京大学 定点突变和定点修饰的腺相关病毒、其制备方法及应用
JP6947739B2 (ja) 2016-02-16 2021-10-13 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 既存のヒト中和抗体に対して耐性である新規組換えアデノ随伴ウイルスカプシド
US20190224339A1 (en) * 2016-04-29 2019-07-25 Voyager Therapeutics, Inc. Compositions for the treatment of disease
US11364308B2 (en) * 2016-05-13 2022-06-21 4D Molecular Therapeutics Inc. Adeno-associated virus variant capsids and methods of use thereof
IL315358A (en) * 2016-08-18 2024-11-01 Univ California CRISPR-CAS genome engineering using a modular AAV delivery system
PE20200488A1 (es) * 2017-06-27 2020-03-03 Regeneron Pharma Vectores virales recombinantes con tropismo modificado y usos de estos para la introduccion dirigida de material genetico a celulas humanas
EP3461836A1 (en) * 2017-09-28 2019-04-03 Universität zu Köln Mutated adeno-associated viral capsid proteins for chemical coupling of ligands, nanoparticles or drugs via thioether binding and production method thereof

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