JP2025503637A5 - - Google Patents
Info
- Publication number
- JP2025503637A5 JP2025503637A5 JP2024541135A JP2024541135A JP2025503637A5 JP 2025503637 A5 JP2025503637 A5 JP 2025503637A5 JP 2024541135 A JP2024541135 A JP 2024541135A JP 2024541135 A JP2024541135 A JP 2024541135A JP 2025503637 A5 JP2025503637 A5 JP 2025503637A5
- Authority
- JP
- Japan
- Prior art keywords
- expression cassette
- antibody expression
- promoter
- antibody
- nucleotide sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263297787P | 2022-01-09 | 2022-01-09 | |
| US63/297,787 | 2022-01-09 | ||
| US202263374878P | 2022-09-07 | 2022-09-07 | |
| US63/374,878 | 2022-09-07 | ||
| PCT/US2023/060329 WO2023133561A1 (en) | 2022-01-09 | 2023-01-09 | Vector constructs for delivery of nucleic acids encoding therapeutic anti-igf-1r antibodies and methods of using the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025503637A JP2025503637A (ja) | 2025-02-04 |
| JP2025503637A5 true JP2025503637A5 (https=) | 2026-01-14 |
Family
ID=85383021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024541135A Pending JP2025503637A (ja) | 2022-01-09 | 2023-01-09 | 治療用抗ｉｇｆ－１ｒ抗体をコードする核酸の送達のためのベクター構築物およびそれを使用する方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20250084434A1 (https=) |
| EP (1) | EP4460522A1 (https=) |
| JP (1) | JP2025503637A (https=) |
| KR (1) | KR20240130139A (https=) |
| AU (1) | AU2023205804A1 (https=) |
| CA (1) | CA3247783A1 (https=) |
| CO (1) | CO2024010847A2 (https=) |
| IL (1) | IL314154A (https=) |
| MX (1) | MX2024008509A (https=) |
| WO (1) | WO2023133561A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220267450A1 (en) | 2020-10-14 | 2022-08-25 | Viridian Therapeutics, Inc. | Compositions and methods for treatment of thyroid eye disease |
| EP4384219A4 (en) | 2021-08-10 | 2025-06-18 | Viridian Therapeutics, Inc. | COMPOSITIONS, DOSAGES AND METHODS FOR THE TREATMENT OF THYROID EYE DISEASE |
| KR20260051103A (ko) | 2023-07-07 | 2026-04-15 | 크리야 테라퓨틱스, 인크. | 안과 병리상태를 치료하기 위한 aav 벡터의 안구주위 전달 |
| WO2025039622A1 (zh) * | 2023-08-23 | 2025-02-27 | 上海金珂博生物技术有限公司 | 经修饰的腺相关病毒载体及其在治疗中枢神经系统疾病中的用途 |
| TW202519262A (zh) * | 2023-09-06 | 2025-05-16 | 美商維里迪恩醫療股份有限公司 | 抗ｉｇｆ－１ｒ抗體之醫藥組合物 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US4861719A (en) | 1986-04-25 | 1989-08-29 | Fred Hutchinson Cancer Research Center | DNA constructs for retrovirus packaging cell lines |
| US5356806A (en) | 1987-06-05 | 1994-10-18 | The United States Of America As Represented By The Department Of Health And Human Services | Immortalized human cell lines containing exogenous cytochrome P450 |
| US4937190A (en) | 1987-10-15 | 1990-06-26 | Wisconsin Alumni Research Foundation | Translation enhancer |
| US6174666B1 (en) | 1992-03-27 | 2001-01-16 | The United States Of America As Represented By The Department Of Health And Human Services | Method of eliminating inhibitory/instability regions from mRNA |
| US6204059B1 (en) | 1994-06-30 | 2001-03-20 | University Of Pittsburgh | AAV capsid vehicles for molecular transfer |
| US5892071A (en) | 1994-09-30 | 1999-04-06 | The Reagents Of The University Of California | Cationic transport reagents |
| US5527928A (en) | 1994-09-30 | 1996-06-18 | Nantz; Michael H. | Cationic transport reagents |
| US5869715A (en) | 1995-09-27 | 1999-02-09 | The Reagents Of The University Of California | Polyfunctional cationic cytofectins |
| EP1390490B1 (en) | 2001-05-24 | 2009-04-15 | Genzyme Corporation | Muscle-specific expression vectors |
| EP1506286B1 (en) * | 2002-05-24 | 2014-03-19 | Merck Sharp & Dohme Corp. | Neutralizing human anti-igfr antibody |
| AR046071A1 (es) | 2003-07-10 | 2005-11-23 | Hoffmann La Roche | Anticuerpos contra el receptor i del factor de crecimiento de tipo insulinico y los usos de los mismos |
| EP2018421B1 (en) | 2006-04-28 | 2012-12-19 | The Trustees of the University of Pennsylvania | Scalable production method for aav |
| JP2012515556A (ja) | 2009-01-23 | 2012-07-12 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 低下したエフェクタ機能を有する安定化Ｆｃポリペプチドおよび使用方法 |
| WO2020206098A1 (en) * | 2019-04-03 | 2020-10-08 | Regenxbio Inc. | Gene therapy for eye pathologies |
-
2023
- 2023-01-09 JP JP2024541135A patent/JP2025503637A/ja active Pending
- 2023-01-09 WO PCT/US2023/060329 patent/WO2023133561A1/en not_active Ceased
- 2023-01-09 US US18/727,201 patent/US20250084434A1/en active Pending
- 2023-01-09 MX MX2024008509A patent/MX2024008509A/es unknown
- 2023-01-09 AU AU2023205804A patent/AU2023205804A1/en active Pending
- 2023-01-09 CA CA3247783A patent/CA3247783A1/en active Pending
- 2023-01-09 IL IL314154A patent/IL314154A/en unknown
- 2023-01-09 EP EP23707576.7A patent/EP4460522A1/en active Pending
- 2023-01-09 KR KR1020247026536A patent/KR20240130139A/ko active Pending
-
2024
- 2024-08-09 CO CONC2024/0010847A patent/CO2024010847A2/es unknown
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