JP2022530989A5 - - Google Patents
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- Publication number
- JP2022530989A5 JP2022530989A5 JP2021564996A JP2021564996A JP2022530989A5 JP 2022530989 A5 JP2022530989 A5 JP 2022530989A5 JP 2021564996 A JP2021564996 A JP 2021564996A JP 2021564996 A JP2021564996 A JP 2021564996A JP 2022530989 A5 JP2022530989 A5 JP 2022530989A5
- Authority
- JP
- Japan
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962842861P | 2019-05-03 | 2019-05-03 | |
| US201962842855P | 2019-05-03 | 2019-05-03 | |
| US201962842858P | 2019-05-03 | 2019-05-03 | |
| US62/842,858 | 2019-05-03 | ||
| US62/842,861 | 2019-05-03 | ||
| US62/842,855 | 2019-05-03 | ||
| US202062982858P | 2020-02-28 | 2020-02-28 | |
| US62/982,858 | 2020-02-28 | ||
| PCT/US2020/031039 WO2020227097A1 (en) | 2019-05-03 | 2020-05-01 | Kcnt1 inhibitors and methods of use |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022530989A JP2022530989A (ja) | 2022-07-05 |
| JPWO2020227097A5 JPWO2020227097A5 (https=) | 2023-05-11 |
| JP2022530989A5 true JP2022530989A5 (https=) | 2023-05-11 |
| JP7671990B2 JP7671990B2 (ja) | 2025-05-07 |
Family
ID=73050875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021564996A Active JP7671990B2 (ja) | 2019-05-03 | 2020-05-01 | Ｋｃｎｔ１阻害剤および使用する方法 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20220280476A1 (https=) |
| EP (2) | EP3962479B1 (https=) |
| JP (1) | JP7671990B2 (https=) |
| KR (2) | KR20250172745A (https=) |
| CN (1) | CN114206335B (https=) |
| AU (2) | AU2020267355B2 (https=) |
| BR (1) | BR112021022061A2 (https=) |
| CA (1) | CA3139062A1 (https=) |
| CL (1) | CL2021002876A1 (https=) |
| CO (1) | CO2021016469A2 (https=) |
| EC (1) | ECSP21087657A (https=) |
| IL (2) | IL287751B2 (https=) |
| MX (1) | MX2021013422A (https=) |
| PE (1) | PE20220017A1 (https=) |
| SA (1) | SA521430753B1 (https=) |
| SG (1) | SG11202112212WA (https=) |
| WO (1) | WO2020227097A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7066871B2 (ja) | 2017-12-15 | 2022-05-13 | シロニックス リニューアブルス，インコーポレイティド | 界面活性剤を形成するための反応性蒸留 |
| US10934266B2 (en) | 2018-07-12 | 2021-03-02 | Sironix Renewables, Inc. | Surfactants from long-chain carbon-containing molecules |
| GB201905721D0 (en) | 2019-04-24 | 2019-06-05 | Univ Dundee | Compounds |
| KR20250172745A (ko) * | 2019-05-03 | 2025-12-09 | 프락시스 프리시젼 메디신즈, 인크. | Kcnt1 억제제 및 사용 방법 |
| JP7699836B2 (ja) | 2020-02-28 | 2025-06-30 | プラクシス プレシジョン メディシンズ， インコーポレイテッド | Ｋｃｎｔ１阻害剤、および使用方法 |
| EP4146151A4 (en) | 2020-05-04 | 2024-12-11 | Sironix Renewables, Inc. | FURANIC SURFACTANT COMPOSITIONS AND METHODS |
| CA3188825A1 (en) * | 2020-07-06 | 2022-01-13 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors and methods of use |
| US11773088B2 (en) | 2020-11-02 | 2023-10-03 | Praxis Precision Medicines, Inc. | KCNT1 inhibitors and methods of use |
| WO2022140547A2 (en) * | 2020-12-22 | 2022-06-30 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors and methods of use |
| WO2022231872A1 (en) * | 2021-04-29 | 2022-11-03 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors and methods of use |
| MX2024007031A (es) | 2021-12-10 | 2024-11-08 | Sironix Renewables Inc | Ajustar sulfonacion y controlar composiciones surfactantes de oleo-furano |
| WO2023211855A1 (en) * | 2022-04-25 | 2023-11-02 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors comprising a thiophene core and methods of use |
| EP4630399A1 (en) * | 2022-12-05 | 2025-10-15 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors comprising a phenyl, pyridine, or pyrimidine core and methods of use |
| WO2025117662A1 (en) * | 2023-11-29 | 2025-06-05 | Actio Biosciences, Inc. | Heterocyclic compounds useful as kcnt1 inhibitors |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US4326525A (en) | 1980-10-14 | 1982-04-27 | Alza Corporation | Osmotic device that improves delivery properties of agent in situ |
| US5364620A (en) | 1983-12-22 | 1994-11-15 | Elan Corporation, Plc | Controlled absorption diltiazem formulation for once daily administration |
| US5023252A (en) | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
| US5001139A (en) | 1987-06-12 | 1991-03-19 | American Cyanamid Company | Enchancers for the transdermal flux of nivadipine |
| US4992445A (en) | 1987-06-12 | 1991-02-12 | American Cyanamid Co. | Transdermal delivery of pharmaceuticals |
| US4902514A (en) | 1988-07-21 | 1990-02-20 | Alza Corporation | Dosage form for administering nilvadipine for treating cardiovascular symptoms |
| DE19929076A1 (de) | 1999-06-25 | 2000-12-28 | Aventis Pharma Gmbh | Indanylsubstituierte Benzolcarbonamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
| AU5464901A (en) * | 2000-03-01 | 2001-09-12 | Nihon Bayer Agrochem K.K. | Dichloropyridyl- and dichloroisothiazolyl-thiocarboxamides and their use as microbicides |
| TWI243164B (en) * | 2001-02-13 | 2005-11-11 | Aventis Pharma Gmbh | Acylated indanyl amines and their use as pharmaceuticals |
| WO2005066137A1 (en) * | 2003-12-19 | 2005-07-21 | Neurogen Corporation | 2,5-diaryl-1h-imidazole-4-carboxamides as neurokinin-3 receptor modulators for the treatment of central nervous system and peripheral diseases |
| EP1838690A2 (en) | 2004-12-21 | 2007-10-03 | Devgen N.V. | Compounds with kv4 ion channel activity |
| WO2018204765A1 (en) * | 2017-05-05 | 2018-11-08 | Pairnomix, Llc | Methods of treating epilepsy and kcnq2 related conditions |
| US20200129538A1 (en) * | 2017-06-13 | 2020-04-30 | The Florey Institute Of Neuroscience And Mental Health | Compositions and methods for treating conditions associated with gain-of-function mutations in kcnt1 |
| BR112020014428A2 (pt) * | 2018-01-19 | 2020-12-01 | Cytokinetics, Inc. | composto, composição farmacêutica, e, métodos para o tratamento de uma doença cardíaca em um indivíduo, para o tratamento de uma doença ou condição que está associada com cavidade ventricular esquerda pequena e obliteração da cavidade, contração hiperdinâmica do ventrículo esquerdo, isquemia do miocárdio ou fibrose cardíaca, para o tratamento de uma doença ou condição selecionada dentre distrofias musculares e doenças de armazenamento do glicogênio e para inibição do sarcômero cardíaco |
| CN108517358A (zh) * | 2018-04-09 | 2018-09-11 | 重庆医科大学附属第医院 | 一种辅助癫痫诊断的标志物及其检测试剂盒 |
| KR20250172745A (ko) * | 2019-05-03 | 2025-12-09 | 프락시스 프리시젼 메디신즈, 인크. | Kcnt1 억제제 및 사용 방법 |
| KR20220016086A (ko) * | 2019-05-03 | 2022-02-08 | 프락시스 프리시젼 메디신즈, 인크. | Kcnt1 억제제 및 사용 방법 |
| US11767325B2 (en) * | 2019-11-26 | 2023-09-26 | Praxis Precision Medicines, Inc. | Substituted [1,2,4]triazolo[4,3-a]pyrazines as ion channel modulators |
| JP7699836B2 (ja) * | 2020-02-28 | 2025-06-30 | プラクシス プレシジョン メディシンズ， インコーポレイテッド | Ｋｃｎｔ１阻害剤、および使用方法 |
| KR20230005168A (ko) * | 2020-03-23 | 2023-01-09 | 프락시스 프리시젼 메디신즈, 인크. | Kcnt1 억제제 및 사용 방법 |
| CA3188825A1 (en) * | 2020-07-06 | 2022-01-13 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors and methods of use |
| US11773088B2 (en) * | 2020-11-02 | 2023-10-03 | Praxis Precision Medicines, Inc. | KCNT1 inhibitors and methods of use |
| WO2022140547A2 (en) * | 2020-12-22 | 2022-06-30 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors and methods of use |
-
2020
- 2020-05-01 KR KR1020257039837A patent/KR20250172745A/ko active Pending
- 2020-05-01 JP JP2021564996A patent/JP7671990B2/ja active Active
- 2020-05-01 SG SG11202112212WA patent/SG11202112212WA/en unknown
- 2020-05-01 IL IL287751A patent/IL287751B2/en unknown
- 2020-05-01 AU AU2020267355A patent/AU2020267355B2/en active Active
- 2020-05-01 EP EP20802501.5A patent/EP3962479B1/en active Active
- 2020-05-01 BR BR112021022061A patent/BR112021022061A2/pt unknown
- 2020-05-01 MX MX2021013422A patent/MX2021013422A/es unknown
- 2020-05-01 US US17/607,815 patent/US20220280476A1/en active Pending
- 2020-05-01 WO PCT/US2020/031039 patent/WO2020227097A1/en not_active Ceased
- 2020-05-01 EP EP24190103.2A patent/EP4446314A3/en active Pending
- 2020-05-01 PE PE2021001829A patent/PE20220017A1/es unknown
- 2020-05-01 CA CA3139062A patent/CA3139062A1/en active Pending
- 2020-05-01 CN CN202080047481.5A patent/CN114206335B/zh active Active
- 2020-05-01 IL IL317949A patent/IL317949A/en unknown
- 2020-05-01 KR KR1020217039175A patent/KR102894020B1/ko active Active
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2021
- 2021-11-02 CL CL2021002876A patent/CL2021002876A1/es unknown
- 2021-11-03 SA SA521430753A patent/SA521430753B1/ar unknown
- 2021-12-02 CO CONC2021/0016469A patent/CO2021016469A2/es unknown
- 2021-12-02 EC ECSENADI202187657A patent/ECSP21087657A/es unknown
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2025
- 2025-08-18 AU AU2025217427A patent/AU2025217427A1/en active Pending