JP2022528780A5 - - Google Patents
Info
- Publication number
- JP2022528780A5 JP2022528780A5 JP2021560707A JP2021560707A JP2022528780A5 JP 2022528780 A5 JP2022528780 A5 JP 2022528780A5 JP 2021560707 A JP2021560707 A JP 2021560707A JP 2021560707 A JP2021560707 A JP 2021560707A JP 2022528780 A5 JP2022528780 A5 JP 2022528780A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- compound
- compound according
- inhibitors
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962833364P | 2019-04-12 | 2019-04-12 | |
| US62/833,364 | 2019-04-12 | ||
| PCT/US2020/027453 WO2020210481A1 (en) | 2019-04-12 | 2020-04-09 | Heterocyclic compounds as kinase inhibitors for therapeutic uses |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022528780A JP2022528780A (ja) | 2022-06-15 |
| JP2022528780A5 true JP2022528780A5 (https=) | 2023-04-17 |
| JP7568641B2 JP7568641B2 (ja) | 2024-10-16 |
Family
ID=72751520
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021560707A Active JP7568641B2 (ja) | 2019-04-12 | 2020-04-09 | 治療的使用のためのキナーゼ阻害剤としての複素環式化合物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220213064A1 (https=) |
| EP (1) | EP3952865A4 (https=) |
| JP (1) | JP7568641B2 (https=) |
| KR (1) | KR102913995B1 (https=) |
| CN (1) | CN114025755B (https=) |
| AU (1) | AU2020271855B2 (https=) |
| CA (1) | CA3132855A1 (https=) |
| TW (1) | TWI757722B (https=) |
| WO (1) | WO2020210481A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12522583B2 (en) | 2018-11-07 | 2026-01-13 | Dana-Farber Cancer Institute, Inc. | Benzimidazole derivatives and aza-benzimidazole derivatives as Janus kinase 2 inhibitors and uses thereof |
| EP3877371A4 (en) | 2018-11-07 | 2022-07-27 | Dana-Farber Cancer Institute, Inc. | IMIDAZOPYRIDINE DERIVATIVES AND AZA-IMIDAZOPYRIDINE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF |
| EP3876939A4 (en) | 2018-11-07 | 2022-08-10 | Dana-Farber Cancer Institute, Inc. | Benzothiazole derivatives and 7-aza-benzothiazole derivatives as janus kinase 2 inhibitors and uses thereof |
| US11691963B2 (en) | 2020-05-06 | 2023-07-04 | Ajax Therapeutics, Inc. | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors |
| US12043632B2 (en) | 2020-12-23 | 2024-07-23 | Ajax Therapeutics, Inc. | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors |
| WO2023086319A1 (en) | 2021-11-09 | 2023-05-19 | Ajax Therapeutics, Inc. | 6-he tero aryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors |
| US12162881B2 (en) | 2021-11-09 | 2024-12-10 | Ajax Therapeutics, Inc. | Forms and compositions of inhibitors of JAK2 |
| CN114031561B (zh) * | 2021-12-10 | 2022-12-02 | 江西科技师范大学 | 含4-苯氧基喹唑啉类化合物及其应用 |
| KR102910577B1 (ko) * | 2022-02-17 | 2026-01-08 | 내셔날 헬스 리서치 인스티튜트 | 융합 다환식 화합물의 제조 방법 |
| CN116763787A (zh) * | 2022-03-08 | 2023-09-19 | 安徽中科拓苒药物科学研究有限公司 | 喹啉类化合物的新用途 |
| CN121219264A (zh) * | 2023-05-12 | 2025-12-26 | 正大天晴药业集团股份有限公司 | 含有芳香双并环的化合物 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1140840E (pt) * | 1999-01-13 | 2006-05-31 | Bayer Pharmaceuticals Corp | Difenilureias substituidas com (.)-carboxiarilo como inibidores de raf-quinase |
| EP1158985B1 (en) * | 1999-01-13 | 2011-12-28 | Bayer HealthCare LLC | OMEGA-CARBOXY ARYL SUBSTITUTED DIPHENYL UREAS AS p38 KINASE INHIBITORS |
| AU9598601A (en) * | 2000-10-20 | 2002-04-29 | Eisai Co Ltd | Nitrogenous aromatic ring compounds |
| EP2210607B1 (en) * | 2003-09-26 | 2011-08-17 | Exelixis Inc. | N-[3-fluoro-4-({6-(methyloxy)-7-[(3-morpholin-4-ylpropyl)oxy]quinolin-4-yl}oxy)phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide for the treatment of cancer |
| AU2004309166B2 (en) | 2003-12-23 | 2008-02-21 | Pfizer Inc. | Novel quinoline derivatives |
| GB0509224D0 (en) * | 2005-05-05 | 2005-06-15 | Chroma Therapeutics Ltd | Inhibitors of intracellular enzymatic activity |
| CA2649288C (en) | 2006-04-19 | 2015-11-24 | Novartis Ag | 6-o-substituted benzoxazole and benzothiazole compounds and methods of inhibiting csf-1r signaling |
| AU2008254425A1 (en) | 2007-05-21 | 2008-11-27 | Novartis Ag | CSF-1R inhibitors, compositions, and methods of use |
| CN101372475B (zh) * | 2008-03-19 | 2012-01-04 | 南京工业大学 | 芳杂环取代的二苯脲类衍生物及其用途 |
| JO3265B1 (ar) | 2008-12-09 | 2018-09-16 | Novartis Ag | مثبطات بيريديلوكسى اندولات vegf-r2 واستخدامها لعلاج المرض |
| KR101106050B1 (ko) | 2009-03-25 | 2012-01-18 | 한국과학기술연구원 | 아미노퀴놀린 화합물, 이의 제조 방법 및 이를 함유하는 의약 조성물 |
| CN101671301B (zh) * | 2009-05-05 | 2014-02-26 | 江苏省药物研究所有限公司 | 杂环取代的二苯脲类衍生物及其用途 |
| US9358235B2 (en) * | 2012-03-19 | 2016-06-07 | Plexxikon Inc. | Kinase modulation, and indications therefor |
| CN104177346A (zh) | 2013-05-21 | 2014-12-03 | 苏州科捷生物医药有限公司 | 喹唑啉类化合物及其用途 |
| WO2016161952A1 (zh) | 2015-04-07 | 2016-10-13 | 广东众生药业股份有限公司 | 酪氨酸激酶抑制剂及包含该酪氨酸激酶抑制剂的药物组合物 |
| ES2913048T3 (es) * | 2015-09-21 | 2022-05-31 | Opna Immuno Oncology Sa | Compuestos heterocíclicos y usos de estos |
| ES2904615T3 (es) * | 2016-03-16 | 2022-04-05 | Plexxikon Inc | Compuestos y métodos para la modulación de quinasas e indicaciones al respecto |
-
2020
- 2020-04-09 US US17/603,273 patent/US20220213064A1/en active Pending
- 2020-04-09 WO PCT/US2020/027453 patent/WO2020210481A1/en not_active Ceased
- 2020-04-09 EP EP20787959.4A patent/EP3952865A4/en active Pending
- 2020-04-09 AU AU2020271855A patent/AU2020271855B2/en active Active
- 2020-04-09 CN CN202080024676.8A patent/CN114025755B/zh active Active
- 2020-04-09 CA CA3132855A patent/CA3132855A1/en active Pending
- 2020-04-09 KR KR1020217032764A patent/KR102913995B1/ko active Active
- 2020-04-09 JP JP2021560707A patent/JP7568641B2/ja active Active
- 2020-04-10 TW TW109112137A patent/TWI757722B/zh active
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