JP2022525435A5 - - Google Patents

Info

Publication number
JP2022525435A5
JP2022525435A5 JP2021559648A JP2021559648A JP2022525435A5 JP 2022525435 A5 JP2022525435 A5 JP 2022525435A5 JP 2021559648 A JP2021559648 A JP 2021559648A JP 2021559648 A JP2021559648 A JP 2021559648A JP 2022525435 A5 JP2022525435 A5 JP 2022525435A5
Authority
JP
Japan
Prior art keywords
antibody
antigen
binding fragment
seq
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021559648A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022525435A (ja
JP7730295B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/027071 external-priority patent/WO2020210232A1/en
Publication of JP2022525435A publication Critical patent/JP2022525435A/ja
Publication of JP2022525435A5 publication Critical patent/JP2022525435A5/ja
Application granted granted Critical
Publication of JP7730295B2 publication Critical patent/JP7730295B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021559648A 2019-04-08 2020-04-07 Cd19抗体およびこれを使用する方法 Active JP7730295B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962831123P 2019-04-08 2019-04-08
US62/831,123 2019-04-08
PCT/US2020/027071 WO2020210232A1 (en) 2019-04-08 2020-04-07 Cd19 antibodies and methods of using the same

Publications (3)

Publication Number Publication Date
JP2022525435A JP2022525435A (ja) 2022-05-13
JP2022525435A5 true JP2022525435A5 (cg-RX-API-DMAC10.html) 2023-04-13
JP7730295B2 JP7730295B2 (ja) 2025-08-27

Family

ID=72751761

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021559648A Active JP7730295B2 (ja) 2019-04-08 2020-04-07 Cd19抗体およびこれを使用する方法

Country Status (9)

Country Link
US (1) US12612456B2 (cg-RX-API-DMAC10.html)
EP (1) EP3953385A4 (cg-RX-API-DMAC10.html)
JP (1) JP7730295B2 (cg-RX-API-DMAC10.html)
KR (1) KR20220006065A (cg-RX-API-DMAC10.html)
CN (1) CN114341176A (cg-RX-API-DMAC10.html)
AU (1) AU2020270888A1 (cg-RX-API-DMAC10.html)
CA (1) CA3136251A1 (cg-RX-API-DMAC10.html)
IL (1) IL287039A (cg-RX-API-DMAC10.html)
WO (1) WO2020210232A1 (cg-RX-API-DMAC10.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113226340A (zh) 2018-11-26 2021-08-06 恩卡尔塔公司 同时扩增多种免疫细胞类型的方法、相关组合物及其在癌症免疫疗法中的用途
KR20210137085A (ko) 2019-03-05 2021-11-17 엔카르타, 인크. Cd19 유도된 키메라 항원 수용체 및 면역 요법에서 이의 용도
JP7137696B2 (ja) 2019-05-14 2022-09-14 プロヴェンション・バイオ・インコーポレイテッド 1型糖尿病を予防するための方法および組成物
GB202002581D0 (en) 2020-02-24 2020-04-08 Gammadelta Therapeutics Ltd Novel antibodies
KR20230092863A (ko) 2020-06-11 2023-06-26 프로벤션 바이오, 인코포레이티드 제1형 당뇨병을 예방하기 위한 방법 및 조성물
ES2943063T5 (en) 2020-08-14 2026-05-05 Gammadelta Therapeutics Ltd Multispecific anti-tcr delta variable 1 antibodies
KR20230160253A (ko) 2021-02-17 2023-11-23 감마델타 테라퓨틱스 엘티디 항-tcr 델타 가변 1 항체
CA3214628A1 (en) * 2021-04-06 2022-10-13 Memorial Sloan-Kettering Cancer Center Combination therapy with dexamethasone and tumor-specific t cell engaging multi-specific antibodies for treating cancer
MX2023013851A (es) 2021-05-24 2023-12-08 Provention Bio Inc Metodos para el tratamiento de diabetes tipo 1.
JP2024546804A (ja) * 2021-12-15 2024-12-26 ワイ-マブス セラピューティクス, インコーポレイテッド Sada複合体を含む製剤
CN119350497A (zh) * 2023-07-24 2025-01-24 星尘生物科技(上海)有限公司 人源化抗cd19单链可变区片段及其用途
WO2025077871A1 (zh) * 2023-10-13 2025-04-17 苏州瑞博生物技术股份有限公司 缀合物、药物缀合物与组合物及制备方法和用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2753158A1 (en) 2009-02-23 2010-08-26 Glenmark Pharmaceuticals S.A. Humanized antibodies that bind to cd19 and their uses
GB201106357D0 (en) * 2011-04-14 2011-06-01 Pessi Antonello Composition and uses thereof
AU2013302696B9 (en) * 2012-08-14 2018-08-09 Ibc Pharmaceuticals, Inc. T-cell redirecting bispecific antibodies for treatment of disease
UY35468A (es) 2013-03-16 2014-10-31 Novartis Ag Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
US20160326249A1 (en) 2014-01-15 2016-11-10 Zymeworks Inc. Bi-specific cd3 and cd19 antigen-binding constructs
MX386342B (es) * 2014-07-25 2025-03-18 Memorial Sloan Kettering Cancer Center Móleculas de unión a her2 y cd3 biespecíficas.
US11820832B2 (en) * 2014-07-25 2023-11-21 Memorial Sloan Kettering Cancer Center Bispecific HER2 and CD3 binding molecules
EA201790719A1 (ru) 2014-09-26 2017-07-31 Макродженикс, Инк. Биспецифические моновалентные диатела, которые способны связывать cd19 и cd3, а также их применения
EA039859B1 (ru) 2015-07-31 2022-03-21 Эмджен Рисерч (Мюник) Гмбх Биспецифические конструкты антител, связывающие egfrviii и cd3
EP3529268B1 (en) 2016-10-19 2025-02-26 The Scripps Research Institute Chimeric antigen receptor effector cell switches with humanized targeting moieties and/or optimized chimeric antigen receptor interacting domains and uses thereof
US11046768B2 (en) * 2017-01-27 2021-06-29 Memorial Sloan Kettering Cancer Center Bispecific HER2 and CD3 binding molecules
KR20190140943A (ko) * 2017-04-24 2019-12-20 메모리얼 슬로안 케터링 캔서 센터 항-cd33 항체 제제
BR102018008260A2 (pt) 2017-04-24 2020-04-28 Kite Pharma, Inc. domínios de ligação ao antígeno humanizado e métodos de uso
CA3067351A1 (en) * 2017-06-15 2018-12-20 Nai-Kong Cheung Anti-l1-cam antibodies and uses thereof
CN109535257B (zh) * 2017-09-22 2021-05-28 同润生物医药(上海)有限公司 新型双特异性cd3/cd19多肽复合物
IL273484B2 (en) 2017-09-23 2025-12-01 Memorial Sloan Kettering Cancer Center A33 antibody compositions and methods of using the same in radioimmunotherapy

Similar Documents

Publication Publication Date Title
JP2022546572A5 (cg-RX-API-DMAC10.html)
CN102174108B (zh) 内在化抗-cd74抗体和使用方法
JP4733635B2 (ja) 抗cd19抗体
CA2529496C (en) Anti-cd74 immunoconjugates and methods
JP7730295B2 (ja) Cd19抗体およびこれを使用する方法
JP2022538117A5 (cg-RX-API-DMAC10.html)
JP2023537002A5 (cg-RX-API-DMAC10.html)
JP2023523584A5 (cg-RX-API-DMAC10.html)
JP2021517816A5 (cg-RX-API-DMAC10.html)
IL273484B1 (en) A33 antibody compositions and methods of using the same in radioimmunotherapy
KR20050027274A (ko) 알파 태아 단백질 Immu31 항체 및 융합단백질, 및이들의 이용 방법
JP2020523029A5 (cg-RX-API-DMAC10.html)
CN101796073B (zh) 针对cxcr3的人源化抗体
US20250340637A1 (en) Cd3 targeting antibodies and uses thereof
JP2024530166A5 (cg-RX-API-DMAC10.html)
CN111065409A (zh) Strep-tag特异性结合蛋白及其用途
CN117279950B (zh) 一种靶向il-18bp的抗体及其应用
JP2025530159A (ja) Ccr8抗体の医学的使用および投与スケジュール
CN117794568A (zh) 抗gpa33多特异性抗体和其用途
JP2026512261A (ja) Cd3を標的とする抗体およびその使用
CN117177999A (zh) 一种靶向IL-18Rβ的抗体及其应用
JP2024514830A5 (cg-RX-API-DMAC10.html)
WO2019197974A1 (en) Anti-telomerase reverse transcriptase antibodies and use thereof
CN119505001B (zh) 靶向cd22的全人源抗体及其应用
JP2024531913A5 (cg-RX-API-DMAC10.html)