JP2024530166A5 - - Google Patents

Info

Publication number
JP2024530166A5
JP2024530166A5 JP2024506663A JP2024506663A JP2024530166A5 JP 2024530166 A5 JP2024530166 A5 JP 2024530166A5 JP 2024506663 A JP2024506663 A JP 2024506663A JP 2024506663 A JP2024506663 A JP 2024506663A JP 2024530166 A5 JP2024530166 A5 JP 2024530166A5
Authority
JP
Japan
Prior art keywords
sequence
seq
cancer
antibody
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024506663A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024530166A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/039301 external-priority patent/WO2023014809A2/en
Publication of JP2024530166A publication Critical patent/JP2024530166A/ja
Publication of JP2024530166A5 publication Critical patent/JP2024530166A5/ja
Pending legal-status Critical Current

Links

JP2024506663A 2021-08-04 2022-08-03 Cd3標的化抗体及びそれらの使用 Pending JP2024530166A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163229125P 2021-08-04 2021-08-04
US63/229,125 2021-08-04
PCT/US2022/039301 WO2023014809A2 (en) 2021-08-04 2022-08-03 Cd3 targeting antibodies and uses thereof

Publications (2)

Publication Number Publication Date
JP2024530166A JP2024530166A (ja) 2024-08-16
JP2024530166A5 true JP2024530166A5 (cg-RX-API-DMAC10.html) 2025-08-13

Family

ID=85156302

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024506663A Pending JP2024530166A (ja) 2021-08-04 2022-08-03 Cd3標的化抗体及びそれらの使用

Country Status (8)

Country Link
US (1) US20250340637A1 (cg-RX-API-DMAC10.html)
EP (1) EP4380631A4 (cg-RX-API-DMAC10.html)
JP (1) JP2024530166A (cg-RX-API-DMAC10.html)
KR (1) KR20240040097A (cg-RX-API-DMAC10.html)
CN (1) CN118043357A (cg-RX-API-DMAC10.html)
AU (1) AU2022323246A1 (cg-RX-API-DMAC10.html)
CA (1) CA3228257A1 (cg-RX-API-DMAC10.html)
WO (1) WO2023014809A2 (cg-RX-API-DMAC10.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12435444B2 (en) 2021-03-09 2025-10-07 Cdr-Life Ag Rabbit-derived antigen binding protein nucleic acid libraries and methods of making the same
EP4304726A1 (en) 2021-03-09 2024-01-17 CDR-Life AG Mage-a4 peptide-mhc antigen binding proteins
EP4587046A1 (en) 2022-09-14 2025-07-23 CDR-Life AG Mage-a4 peptide dual t cell engagers
CN116574182B (zh) * 2023-06-09 2024-02-06 上海交通大学医学院附属第九人民医院 一种抗人Ki-67抗体及其制备方法和用途
CN118027196B (zh) * 2023-06-25 2025-12-02 合肥天港免疫药物有限公司 抗cd3抗体及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP2016009222A0 (en) * 2013-11-04 2016-05-31 Glenmark Pharmaceuticals Sa Production of t cell retargeting hetero-dimeric immunoglobulins
MA40894A (fr) * 2014-11-04 2017-09-12 Glenmark Pharmaceuticals Sa Immunoglobulines hétéro-dimères reciblant des lymphocytes t cd3/cd38 et leurs procédés de production
FI3322727T3 (fi) * 2015-07-15 2026-03-17 Genmab As Humanisoituja tai kimeerisiä CD3-vasta-aineita
CN110913895B (zh) * 2017-05-08 2024-04-02 阿迪马布有限责任公司 抗cd3结合结构域和包含它们的抗体以及它们的产生及使用方法
US11472880B2 (en) * 2017-08-14 2022-10-18 Morphosys Ag Humanized antibodies for CD3
CN110305217B (zh) * 2018-03-27 2022-03-29 广州爱思迈生物医药科技有限公司 双特异性抗体及其应用
KR102239781B1 (ko) * 2019-04-08 2021-04-13 주식회사 녹십자 Gpnmb 및 cd3에 특이적으로 결합하는 이중특이적 항체 및 이의 용도
CN120842421A (zh) * 2019-07-30 2025-10-28 魁尔斯弗生物治疗股份有限公司 双特异性抗LRRC15和CD3ε抗体

Similar Documents

Publication Publication Date Title
JP2023523584A5 (cg-RX-API-DMAC10.html)
JP2022546572A5 (cg-RX-API-DMAC10.html)
JP2023537002A5 (cg-RX-API-DMAC10.html)
Paul et al. Cancer therapy with antibodies
Friedman et al. Engineered affinity proteins for tumour‐targeting applications
JP2022525435A5 (cg-RX-API-DMAC10.html)
Thakur et al. Cancer therapy with bispecific antibodies: Clinical experience
Christiansen et al. Biological impediments to monoclonal antibody–based cancer immunotherapy
Cao et al. Bispecific antibodies as novel bioconjugates
JP2020523029A5 (cg-RX-API-DMAC10.html)
JP2022538117A5 (cg-RX-API-DMAC10.html)
IL273484B1 (en) A33 antibody compositions and methods of using the same in radioimmunotherapy
Nielsen et al. Internalizing antibodies and targeted cancer therapy: direct selection from phage display libraries
Chester et al. Engineering antibodies for clinical applications in cancer
JP2021503927A5 (cg-RX-API-DMAC10.html)
RU2017145150A (ru) Антитело против pdl-1, его фармацевтическая композиция и применение
WO2022216965A1 (en) Radioimmunotherapy directed to ccr8 for depletion of tumor infiltrating regulatory t cells
Guo et al. Revolutionizing cancer immunotherapy: unleashing the potential of bispecific antibodies for targeted treatment
JP2020534017A5 (cg-RX-API-DMAC10.html)
Lin et al. The evolution of antibodies into versatile tumor-targeting agents
Dorvillius et al. Targeting of human breast cancer by a bispecific antibody directed against two tumour-associated antigens: ErbB-2 and carcinoembryonic antigen
Sirk et al. Site-specific, thiol-mediated conjugation of fluorescent probes to cysteine-modified diabodies targeting CD20 or HER2
JP2021517816A5 (cg-RX-API-DMAC10.html)
WO2019052508A1 (zh) 放射性标记抗纳米抗体在癌症的预后、诊断中的应用
Shapiro Regulatory considerations in the design, development and quality of monoclonal antibodies and related products for the diagnosis and treatment of cancer