JP2022524753A - 電荷修飾グロビンを含む抗腫瘍細胞 - Google Patents

電荷修飾グロビンを含む抗腫瘍細胞 Download PDF

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JP2022524753A
JP2022524753A JP2021552690A JP2021552690A JP2022524753A JP 2022524753 A JP2022524753 A JP 2022524753A JP 2021552690 A JP2021552690 A JP 2021552690A JP 2021552690 A JP2021552690 A JP 2021552690A JP 2022524753 A JP2022524753 A JP 2022524753A
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cell
globin
cells
antitumor
charge
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JP2022524753A5 (enExample
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ウィリス ペリマン，アダム
マイケル カーター，ベンジャミン
イアン フィリップ グリーン，トーマス
コー，デイヴィッド
ホンユ ジャン，ウィリアム
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サイトシーク リミテッド
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/41—Vertebrate antigens
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    • A—HUMAN NECESSITIES
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    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
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    • A61K9/00—Medicinal preparations characterised by special physical form
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    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
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    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4716—Muscle proteins, e.g. myosin, actin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/49—Breast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/56—Kidney
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
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  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2021552690A 2019-03-06 2020-03-06 電荷修飾グロビンを含む抗腫瘍細胞 Pending JP2022524753A (ja)

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GBGB1902992.5A GB201902992D0 (en) 2019-03-06 2019-03-06 Product and method
GB1902992.5 2019-03-06
PCT/GB2020/050537 WO2020178598A1 (en) 2019-03-06 2020-03-06 Antitumor cell comprising a charge modified globin

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JP2022524753A true JP2022524753A (ja) 2022-05-10
JP2022524753A5 JP2022524753A5 (enExample) 2023-03-09

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US (1) US20220127317A1 (enExample)
EP (1) EP3934667A1 (enExample)
JP (1) JP2022524753A (enExample)
KR (1) KR20210135567A (enExample)
CN (1) CN113891719A (enExample)
AU (1) AU2020231078A1 (enExample)
CA (1) CA3131161A1 (enExample)
GB (1) GB201902992D0 (enExample)
WO (1) WO2020178598A1 (enExample)

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US20260234195A1 (en) * 2021-11-05 2026-08-13 University Of Kansas Active immunization against amyloid and aging-related diseases
GB202200962D0 (en) 2022-01-25 2022-03-09 Cytoseek Ltd Polymer additives
WO2025137409A1 (en) * 2023-12-21 2025-06-26 University Of Florida Research Foundation, Incorporated Supercharged lipid nanodiscs and methods of use

Citations (1)

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JP2012525146A (ja) * 2009-04-28 2012-10-22 プレジデント アンド フェロウズ オブ ハーバード カレッジ 細胞透過のための過剰に荷電されたタンパク質

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EP2297182A4 (en) 2008-04-28 2012-08-15 Harvard College HIGHLY CHARGED PROTEINS USED FOR CELL PENETRATION
JP2010215517A (ja) * 2009-03-13 2010-09-30 Terumo Corp 酸素親和性を中酸素親和性に制御したヘモグロビン含有リポソーム懸濁液
CA2849448C (en) * 2011-09-06 2020-03-24 Billion King International Limited Oral delivery for hemoglobin based oxygen carriers
FR3002146B1 (fr) 2013-02-15 2016-03-04 Hemarina Utilisation d'hemoglobine d'annelides pour traiter les cancers
JP6618892B2 (ja) 2013-04-23 2019-12-11 プレジデント アンド フェローズ オブ ハーバード カレッジ 細菌バイオフィルムの遺伝的リプログラミング
EP3043819A4 (en) * 2013-09-11 2017-04-05 Compugen Ltd. Anti-vstm5 antibodies and the use thereof in therapy and diagnosis
EP3212221B1 (en) 2014-10-29 2023-12-06 Massachusetts Eye & Ear Infirmary Efficient delivery of therapeutic molecules in vitro and in vivo
CN106137967B (zh) * 2015-04-24 2019-05-14 北京大学 靶向脑胶质瘤的双重修饰脂质体给药系统的制备和应用
CN109790519A (zh) * 2016-06-22 2019-05-21 塞尔丽思股份公司 细胞靶向的药物活性物质或标记物递送体系

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
JP2012525146A (ja) * 2009-04-28 2012-10-22 プレジデント アンド フェロウズ オブ ハーバード カレッジ 細胞透過のための過剰に荷電されたタンパク質

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BIOMATERIALS, vol. 182, JPN6024009317, 11 August 2018 (2018-08-11), pages 145 - 156, ISSN: 0005432205 *
NATURE COMMUNICATIONS, vol. Vol.6, Article number:7405, JPN6024009316, 17 June 2015 (2015-06-17), pages 1 - 6, ISSN: 0005432206 *

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US20220127317A1 (en) 2022-04-28
KR20210135567A (ko) 2021-11-15
GB201902992D0 (en) 2019-04-17
EP3934667A1 (en) 2022-01-12
CN113891719A (zh) 2022-01-04
CA3131161A1 (en) 2020-09-10
AU2020231078A1 (en) 2021-10-21
WO2020178598A1 (en) 2020-09-10

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