JP2022522404A5 - - Google Patents
Info
- Publication number
- JP2022522404A5 JP2022522404A5 JP2021543384A JP2021543384A JP2022522404A5 JP 2022522404 A5 JP2022522404 A5 JP 2022522404A5 JP 2021543384 A JP2021543384 A JP 2021543384A JP 2021543384 A JP2021543384 A JP 2021543384A JP 2022522404 A5 JP2022522404 A5 JP 2022522404A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- amino acid
- acid sequence
- mhc class
- terminus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962814715P | 2019-03-06 | 2019-03-06 | |
| US62/814,715 | 2019-03-06 | ||
| PCT/US2020/019244 WO2020180501A1 (en) | 2019-03-06 | 2020-02-21 | T-cell modulatory antigen-presenting polypeptides and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022522404A JP2022522404A (ja) | 2022-04-19 |
| JP2022522404A5 true JP2022522404A5 (https=) | 2023-03-01 |
| JP7691927B2 JP7691927B2 (ja) | 2025-06-12 |
Family
ID=72338064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021543384A Active JP7691927B2 (ja) | 2019-03-06 | 2020-02-21 | T細胞調節抗原提示ポリペプチド及びその使用方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20220106378A1 (https=) |
| EP (1) | EP3935079A4 (https=) |
| JP (1) | JP7691927B2 (https=) |
| WO (1) | WO2020180501A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2973548T3 (es) | 2016-12-22 | 2024-06-20 | Cue Biopharma Inc | Polipéptidos multiméricos moduladores de linfocitos T y métodos para su uso |
| US20200010528A1 (en) | 2017-03-15 | 2020-01-09 | Cue Biopharma, Inc. | Methods for modulating an immune response |
| LT3615674T (lt) | 2017-04-28 | 2024-09-25 | The Regents Of The University Of Colorado, A Body Corporate | Reumatoidinio artrito gydymo būdai, naudojant nukreipiančios rnr hla geno redagavimą genome |
| JP2020534352A (ja) | 2017-09-07 | 2020-11-26 | キュー バイオファーマ,インコーポレーテッド | コンジュゲーション部位を有するt細胞調節多量体ポリペプチド及びその使用方法 |
| WO2021231376A2 (en) | 2020-05-12 | 2021-11-18 | Cue Biopharma, Inc. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
| AU2022263441A1 (en) * | 2021-04-21 | 2023-11-09 | Cue Biopharma, Inc. | Antigen presenting polypeptide complexes bearing tgf-beta and methods of use thereof |
| WO2022226073A1 (en) * | 2021-04-21 | 2022-10-27 | Cue Biopharma, Inc. | Mhc class ii t-cell modulatory polypeptides and methods of use thereof |
| AU2022261908A1 (en) * | 2021-04-21 | 2023-10-05 | Cue Biopharma, Inc. | Mhc class ii t-cell modulatory polypeptides for treating type 1 diabetes mellitus (t1d) and methods of use thereof |
| KR20240023035A (ko) | 2021-05-10 | 2024-02-20 | 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코퍼레이트 | 자가면역 치료를 위한 hla 조작 방법 및 조성물 |
| WO2022251552A2 (en) * | 2021-05-26 | 2022-12-01 | Cue Biopharma, Inc. | Antigen presenting polypeptide complexes and methods of use thereof |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
| DE69233013T2 (de) | 1991-08-20 | 2004-03-04 | The Government Of The United States Of America As Represented By The Secretary Of National Institute Of Health, Office Of Technology Transfer | Adenovirus vermittelter gentransfer in den gastrointestinaltrakt |
| US5252479A (en) | 1991-11-08 | 1993-10-12 | Research Corporation Technologies, Inc. | Safe vector for gene therapy |
| FR2688514A1 (fr) | 1992-03-16 | 1993-09-17 | Centre Nat Rech Scient | Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant. |
| EP1024198A3 (en) | 1992-12-03 | 2002-05-29 | Genzyme Corporation | Pseudo-adenoviral vectors for the gene therapy of haemophiliae |
| EP0705344B8 (en) | 1993-06-24 | 2006-05-10 | Advec Inc. | Adenovirus vectors for gene therapy |
| AU687117B2 (en) | 1993-10-25 | 1998-02-19 | Canji, Inc. | Recombinant adenoviral vector and methods of use |
| WO1996004314A1 (en) * | 1994-07-29 | 1996-02-15 | Dade International, Inc. | Mhc complexes and uses thereof |
| US7078387B1 (en) | 1998-12-28 | 2006-07-18 | Arch Development Corp. | Efficient and stable in vivo gene transfer to cardiomyocytes using recombinant adeno-associated virus vectors |
| US6287860B1 (en) | 2000-01-20 | 2001-09-11 | Isis Pharmaceuticals, Inc. | Antisense inhibition of MEKK2 expression |
| US6811785B2 (en) * | 2001-05-07 | 2004-11-02 | Mount Sinai School Of Medicine Of New York University | Multivalent MHC class II—peptide chimeras |
| EP1578917A4 (en) | 2001-07-19 | 2008-01-23 | Perlan Therapeutics Inc | MULTIMEDIA PROTEINS AND METHODS FOR THE PRODUCTION AND USE THEREOF |
| US10105437B2 (en) | 2004-04-28 | 2018-10-23 | Btg International Limited | Epitopes related to coeliac disease |
| US7855279B2 (en) | 2005-09-27 | 2010-12-21 | Amunix Operating, Inc. | Unstructured recombinant polymers and uses thereof |
| AU2007223855B2 (en) | 2006-03-06 | 2013-05-16 | Amunix Operating Inc. | Unstructured recombinant polymers and uses thereof |
| JP2010536341A (ja) | 2007-08-15 | 2010-12-02 | アムニクス, インコーポレイテッド | 生物学的に活性なポリペプチドの特性を改変するための組成物および方法 |
| ES2610356T3 (es) | 2009-02-03 | 2017-04-27 | Amunix Operating Inc. | Polipéptidos recombinantes extendidos y composiciones que comprenden los mismos |
| US9695410B2 (en) * | 2010-07-15 | 2017-07-04 | Technion Research & Development Foundation Limited | Isolated high affinity entities with T-cell receptor like specificity towards native complexes of MHC class II and glutamic acid decarboxylase (GAD) autoantigenic peptides |
| US10816554B2 (en) * | 2014-04-04 | 2020-10-27 | The Board Of Trustees Of The Leland Stanford Junior University | Ligand discovery for T cell receptors |
| AU2015249592A1 (en) | 2014-04-24 | 2016-12-15 | Immusant, Inc. | Use of Interleukin-2 for diagnosis of Celiac disease |
| WO2015195531A2 (en) * | 2014-06-18 | 2015-12-23 | Albert Einstein College Of Medicine, Inc. | Syntac polypeptides and uses thereof |
| DK3215528T3 (da) * | 2014-11-06 | 2019-10-07 | Hoffmann La Roche | Fc-regionvarianter med modificeret FcRn-binding og anvendelsesfremgangsmåder |
| EP3291832B1 (en) * | 2015-05-06 | 2025-09-03 | UTI Limited Partnership | Nanoparticle compositions for sustained therapy |
| CA3014466A1 (en) * | 2016-03-03 | 2017-09-08 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| CN109689096A (zh) * | 2016-05-18 | 2019-04-26 | 阿尔伯特爱因斯坦医学院公司 | 变体pd-l1多肽、t细胞调节性多聚体多肽及其使用方法 |
| US20180127481A1 (en) * | 2016-11-09 | 2018-05-10 | Uti Limited Partnership | RECOMBINANT pMHC CLASS II MOLECULES |
| EP3678677A4 (en) * | 2017-09-07 | 2021-06-16 | Cue Biopharma, Inc. | Antigen-presenting polypeptides and methods of use thereof |
| WO2022056014A1 (en) * | 2020-09-09 | 2022-03-17 | Cue Biopharma, Inc. | Mhc class ii t-cell modulatory multimeric polypeptides for treating type 1 diabetes mellitus (t1d) and methods of use thereof |
-
2020
- 2020-02-21 EP EP20767049.8A patent/EP3935079A4/en active Pending
- 2020-02-21 WO PCT/US2020/019244 patent/WO2020180501A1/en not_active Ceased
- 2020-02-21 JP JP2021543384A patent/JP7691927B2/ja active Active
-
2021
- 2021-08-05 US US17/394,960 patent/US20220106378A1/en active Pending
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