JP2022522312A5 - - Google Patents
Info
- Publication number
- JP2022522312A5 JP2022522312A5 JP2021559054A JP2021559054A JP2022522312A5 JP 2022522312 A5 JP2022522312 A5 JP 2022522312A5 JP 2021559054 A JP2021559054 A JP 2021559054A JP 2021559054 A JP2021559054 A JP 2021559054A JP 2022522312 A5 JP2022522312 A5 JP 2022522312A5
- Authority
- JP
- Japan
- Prior art keywords
- unsubstituted
- substituted
- alkyl
- monocyclic
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024101773A JP7710215B2 (ja) | 2019-04-03 | 2024-06-25 | ピロール化合物 |
| JP2025110439A JP7811768B2 (ja) | 2019-04-03 | 2025-06-30 | ピロール化合物 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962828919P | 2019-04-03 | 2019-04-03 | |
| US62/828,919 | 2019-04-03 | ||
| US201962932686P | 2019-11-08 | 2019-11-08 | |
| US62/932,686 | 2019-11-08 | ||
| PCT/US2020/026116 WO2020205934A1 (en) | 2019-04-03 | 2020-04-01 | Pyrrole compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024101773A Division JP7710215B2 (ja) | 2019-04-03 | 2024-06-25 | ピロール化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022522312A JP2022522312A (ja) | 2022-04-15 |
| JP2022522312A5 true JP2022522312A5 (https=) | 2023-04-11 |
| JP7627008B2 JP7627008B2 (ja) | 2025-02-05 |
Family
ID=72667046
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021559054A Active JP7627008B2 (ja) | 2019-04-03 | 2020-04-01 | ピロール化合物 |
| JP2024101773A Active JP7710215B2 (ja) | 2019-04-03 | 2024-06-25 | ピロール化合物 |
| JP2025110439A Active JP7811768B2 (ja) | 2019-04-03 | 2025-06-30 | ピロール化合物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024101773A Active JP7710215B2 (ja) | 2019-04-03 | 2024-06-25 | ピロール化合物 |
| JP2025110439A Active JP7811768B2 (ja) | 2019-04-03 | 2025-06-30 | ピロール化合物 |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US11191747B2 (https=) |
| EP (2) | EP3947349B1 (https=) |
| JP (3) | JP7627008B2 (https=) |
| KR (2) | KR102933784B1 (https=) |
| CN (4) | CN114258391A (https=) |
| AU (2) | AU2020253444C1 (https=) |
| BR (1) | BR112021019817A2 (https=) |
| CA (1) | CA3134635A1 (https=) |
| CL (1) | CL2021002575A1 (https=) |
| CO (1) | CO2021014210A2 (https=) |
| DK (1) | DK3947349T3 (https=) |
| FI (1) | FI3947349T3 (https=) |
| GE (2) | GEAP202515762A (https=) |
| IL (1) | IL286902B2 (https=) |
| MA (1) | MA55564A (https=) |
| MX (1) | MX2021012105A (https=) |
| PE (1) | PE20220252A1 (https=) |
| PH (1) | PH12021552513A1 (https=) |
| SG (1) | SG11202110718PA (https=) |
| TW (1) | TWI846853B (https=) |
| UA (1) | UA129029C2 (https=) |
| WO (1) | WO2020205934A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2021012105A (es) | 2019-04-03 | 2021-11-03 | Aligos Therapeutics Inc | Compuestos de pirrol. |
| CN114685514A (zh) * | 2020-12-29 | 2022-07-01 | 广东东阳光药业有限公司 | 新型酰胺吡咯类化合物及其在药物中的应用 |
| WO2022156758A1 (zh) * | 2021-01-22 | 2022-07-28 | 广东东阳光药业有限公司 | 新型酰胺吡咯类化合物及其在药物中的用途 |
| EP4399217A2 (en) | 2021-09-08 | 2024-07-17 | Aligos Therapeutics, Inc. | Modified short interfering nucleic acid (sina) molecules and uses thereof |
| CN118974014B (zh) * | 2022-03-17 | 2026-01-27 | 成都微芯药业有限公司 | 吡咯酰胺类化合物及其制备方法和用途 |
| CN116120219A (zh) * | 2022-12-27 | 2023-05-16 | 吉斯凯(苏州)制药有限公司 | 一种多取代吡咯类化合物及其制备方法和在制备hbv衣壳蛋白抑制剂中的应用 |
| EP4654973A1 (en) * | 2023-01-26 | 2025-12-03 | Aligos Therapeutics, Inc. | Hepatitis b combination therapies |
Family Cites Families (54)
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| US4784782A (en) | 1986-03-27 | 1988-11-15 | The Lubrizol Corporation | Heterocyclic compounds useful as additives for lubricant and fuel compositions |
| HUP0302918A2 (hu) | 2000-07-17 | 2003-12-29 | Ranbaxy Laboratories Limited | Mikrobaellenes oxazolidinonszármazékok és a vegyületeket tartalmazó gyógyászati készítmények és eljárás a vegyületek előállítására |
| ATE427948T1 (de) | 2001-04-24 | 2009-04-15 | Purdue Research Foundation | Folat-mimetika und deren folatrezeptorbindende konjugate |
| US6956040B2 (en) | 2001-07-16 | 2005-10-18 | Ranbaxy Laboratories Limited | Oxazolidinone piperazinyl derivatives as potential antimicrobials |
| GB0119172D0 (en) | 2001-08-06 | 2001-09-26 | Melacure Therapeutics Ab | Phenyl pyrrole derivatives |
| PL377314A1 (pl) | 2002-12-20 | 2006-01-23 | Amgen Inc. | Modulatory astmy i zapaleń na tle alergicznym |
| US7202257B2 (en) | 2003-12-24 | 2007-04-10 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
| GB2398299A (en) | 2003-02-13 | 2004-08-18 | Melacure Therapeutics Ab | Pharmaceutically active phenyl-pyrrole derivatives |
| US20070191336A1 (en) | 2003-12-24 | 2007-08-16 | Flynn Daniel L | Anti-inflammatory medicaments |
| US7732446B1 (en) | 2004-03-11 | 2010-06-08 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| CN100519555C (zh) | 2004-03-13 | 2009-07-29 | Tmrc株式会社 | 将dna的特定碱基序列烷基化的新吲哚衍生物和使用其的烷基化剂以及药剂 |
| US20060102471A1 (en) | 2004-11-18 | 2006-05-18 | Karl Maurer | Electrode array device having an adsorbed porous reaction layer |
| US20060105355A1 (en) | 2004-11-18 | 2006-05-18 | Karl Maurer | Electrode array device having an adsorbed porous reaction layer having a linker moiety |
| WO2006092059A1 (en) | 2005-03-04 | 2006-09-08 | Fan Wu | Design and synthesis of novel antimicrobials |
| US20100234379A1 (en) | 2005-07-28 | 2010-09-16 | Bahr Ben A | Dual modulation of endocannabinoid transport and fatty-acid amide hydrolase for treatment of excitotoxicity |
| US20070065877A1 (en) | 2005-09-19 | 2007-03-22 | Combimatrix Corporation | Microarray having a base cleavable succinate linker |
| ES2565683T3 (es) | 2006-09-15 | 2016-04-06 | Xcovery, Inc. | Compuestos inhibidores de quinasa |
| CA2688136A1 (en) | 2007-06-08 | 2008-12-11 | Advinus Therapeutics Private Limited | Pyrrole-2-carboxamide derivatives as glucokinase activators, their process and pharmaceutical application |
| AU2008266515B2 (en) | 2007-06-18 | 2014-05-01 | Sanofi | Pyrrole derivatives as P2Y12 antagonists |
| CA2754492A1 (en) | 2009-03-05 | 2010-09-10 | Purdue Research Foundation | Method for early imaging of atherosclerosis |
| EP2408770B1 (en) | 2009-03-20 | 2014-11-05 | University Of Virginia Patent Foundation | Broad spectrum benzothiophene-nitrothiazolide and other antimicrobials |
| JP2013508413A (ja) | 2009-10-22 | 2013-03-07 | ヴァンダービルト ユニバーシティー | mGluR4アロステリック増強剤、組成物、および神経機能不全を治療する方法 |
| EP2568809A4 (en) | 2010-05-12 | 2013-11-06 | Univ Vanderbilt | HETEROCYCLIC ALLOSTERE SULFON MGLUR4 POTENTIATORS, COMPOSITIONS AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTIONS |
| CN103068814B (zh) | 2010-06-15 | 2015-11-25 | 拜耳知识产权有限责任公司 | 邻氨基苯甲酸衍生物 |
| PL2616444T3 (pl) | 2010-09-14 | 2016-04-29 | Inst Biochemii I Biofizyki Pan | Związki będące modulatorami zmutowanego białka CFTR oraz ich zastosowanie w leczeniu chorób związanych z zaburzeniami w funkcjonowaniu białka CFTR |
| WO2012047525A2 (en) | 2010-09-27 | 2012-04-12 | Endocyte, Inc. | Folate conjugates for treating inflammation of the eye |
| WO2012078902A2 (en) | 2010-12-08 | 2012-06-14 | Proteostasis Therapeutics, Inc. | Proteostasis regulators |
| WO2012087976A2 (en) | 2010-12-21 | 2012-06-28 | Intermune, Inc. | Novel inhibitors of hepatitis c virus replication |
| WO2012154880A1 (en) | 2011-05-09 | 2012-11-15 | Proteostasis Therapeutics, Inc. | Proteostasis regulators for treating cystic fibrosis and other protein misfolding diseases |
| US20130072473A1 (en) | 2011-05-09 | 2013-03-21 | Proteostasis Therapeutics, Inc. | Compounds for treating protein folding disorders |
| HUE044867T2 (hu) | 2011-05-12 | 2019-11-28 | Proteostasis Therapeutics Inc | Proteosztázis szabályzók |
| JP5977347B2 (ja) | 2011-07-01 | 2016-08-24 | バルーク エス.ブルームバーグ インスティテュート | Hbv感染に対する抗ウイルス剤としてのスルファモイルベンズアミド誘導体 |
| US8835640B1 (en) | 2011-11-16 | 2014-09-16 | Paresh T. Gandhi | Nicotine derivatives |
| EP2804605A4 (en) | 2012-01-20 | 2015-07-08 | Acucela Inc | SUBSTITUTED HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASES |
| EP3345597A3 (en) | 2012-09-19 | 2018-08-22 | Faller & Williams Technology, LLC | Pkc delta inhibitors for use as therapeutics |
| TWI733288B (zh) | 2013-05-17 | 2021-07-11 | 愛爾蘭商健生科學愛爾蘭無限公司 | 胺磺醯基吡咯醯胺衍生物及其作為用於治療b型肝炎藥物的用途 |
| HRP20180791T1 (hr) * | 2013-07-25 | 2018-09-07 | Janssen Sciences Ireland Uc | Glioksamid supstituirani derivati pirolamida i njihova uporaba kao lijekova za liječenje hepatitisa b |
| CA2923712C (en) * | 2013-10-23 | 2021-11-02 | Janssen Sciences Ireland Uc | Carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis b |
| CN104672221B (zh) | 2013-11-29 | 2018-01-23 | 中国科学院上海有机化学研究所 | 一种氟代苯并杂环‑杂芳环结构的合成方法 |
| US10040780B2 (en) | 2014-03-03 | 2018-08-07 | The Regents Of The University Of California | Mcl-1 antagonists |
| DE102014108210A1 (de) | 2014-06-11 | 2015-12-17 | Dietrich Gulba | Rodentizid |
| US20160166679A1 (en) | 2014-12-12 | 2016-06-16 | Purdue Research Foundation | Method of treatment using folate conjugates and tyrosine kinase inhibitors |
| KR101726059B1 (ko) | 2015-07-28 | 2017-04-12 | 한양대학교 산학협력단 | 디피롤 유도체와 암모늄 염을 포함하는 브롬화수소 가스 검출용 조성물 및 이를 포함하는 브롬화수소 가스 검출용 색변환 센서 |
| KR101726060B1 (ko) | 2015-07-28 | 2017-04-12 | 한양대학교 산학협력단 | 디피롤 유도체와 금속 염을 포함하는 염화수소 가스 검출용 조성물 및 이를 포함하는 염화수소 가스 검출용 색변환 센서 |
| WO2017081615A1 (en) | 2015-11-09 | 2017-05-18 | Wockhardt Limited | 7-oxo -6-(sulfooxy)- 1,6-diazabicyclo [3.2.1] octane containing compounds and their use in treatment of bacterial infections |
| CO2018009382A2 (es) * | 2016-03-09 | 2018-09-20 | Univ Emory | Eliminación del virus de la hepatitis b con agentes antivirales |
| JOP20190024A1 (ar) * | 2016-08-26 | 2019-02-19 | Gilead Sciences Inc | مركبات بيروليزين بها استبدال واستخداماتها |
| CN108250121A (zh) | 2016-12-28 | 2018-07-06 | 上海长森药业有限公司 | 磺酰胺-芳基酰胺类化合物及其治疗乙型肝炎的药物用途 |
| WO2019185016A1 (zh) * | 2018-03-30 | 2019-10-03 | 正大天晴药业集团股份有限公司 | 含有n杂五元环的衣壳蛋白装配抑制剂、其药物组合物和用途 |
| US20230056135A1 (en) | 2018-10-05 | 2023-02-23 | Emory University | Monomer and multimeric anti-hbv agents |
| WO2020169784A1 (en) | 2019-02-22 | 2020-08-27 | Janssen Sciences Ireland Unlimited Company | Amide derivatives useful in the treatment of hbv infection or hbv-induced diseases |
| MX2021012105A (es) | 2019-04-03 | 2021-11-03 | Aligos Therapeutics Inc | Compuestos de pirrol. |
| EP4245372A3 (en) | 2019-11-13 | 2023-11-22 | Xi'An Xintong Pharmaceutical Research Co., Ltd. | Hbv inhibitor and use thereof |
| CN114685514A (zh) | 2020-12-29 | 2022-07-01 | 广东东阳光药业有限公司 | 新型酰胺吡咯类化合物及其在药物中的应用 |
-
2020
- 2020-04-01 MX MX2021012105A patent/MX2021012105A/es unknown
- 2020-04-01 CA CA3134635A patent/CA3134635A1/en active Pending
- 2020-04-01 GE GEAP202515762A patent/GEAP202515762A/en unknown
- 2020-04-01 WO PCT/US2020/026116 patent/WO2020205934A1/en not_active Ceased
- 2020-04-01 CN CN202080028131.4A patent/CN114258391A/zh active Pending
- 2020-04-01 CN CN202511436317.4A patent/CN121085825A/zh active Pending
- 2020-04-01 UA UAA202105907A patent/UA129029C2/uk unknown
- 2020-04-01 EP EP20784496.0A patent/EP3947349B1/en active Active
- 2020-04-01 SG SG11202110718PA patent/SG11202110718PA/en unknown
- 2020-04-01 PE PE2021001658A patent/PE20220252A1/es unknown
- 2020-04-01 EP EP26163262.4A patent/EP4733305A2/en active Pending
- 2020-04-01 DK DK20784496.0T patent/DK3947349T3/da active
- 2020-04-01 KR KR1020217035886A patent/KR102933784B1/ko active Active
- 2020-04-01 IL IL286902A patent/IL286902B2/en unknown
- 2020-04-01 CN CN202511435986.XA patent/CN121108187A/zh active Pending
- 2020-04-01 GE GEAP202015762A patent/GEP20257772B/en unknown
- 2020-04-01 PH PH1/2021/552513A patent/PH12021552513A1/en unknown
- 2020-04-01 FI FIEP20784496.0T patent/FI3947349T3/fi active
- 2020-04-01 BR BR112021019817A patent/BR112021019817A2/pt unknown
- 2020-04-01 CN CN202511330314.2A patent/CN121108034A/zh active Pending
- 2020-04-01 KR KR1020267006069A patent/KR20260036605A/ko active Pending
- 2020-04-01 MA MA055564A patent/MA55564A/fr unknown
- 2020-04-01 US US16/837,515 patent/US11191747B2/en active Active
- 2020-04-01 TW TW109111398A patent/TWI846853B/zh active
- 2020-04-01 AU AU2020253444A patent/AU2020253444C1/en active Active
- 2020-04-01 JP JP2021559054A patent/JP7627008B2/ja active Active
-
2021
- 2021-10-01 CL CL2021002575A patent/CL2021002575A1/es unknown
- 2021-10-25 CO CONC2021/0014210A patent/CO2021014210A2/es unknown
- 2021-11-16 US US17/455,178 patent/US11771680B2/en active Active
-
2023
- 2023-08-22 US US18/453,887 patent/US12599582B2/en active Active
-
2024
- 2024-06-25 JP JP2024101773A patent/JP7710215B2/ja active Active
-
2025
- 2025-06-30 JP JP2025110439A patent/JP7811768B2/ja active Active
- 2025-08-13 AU AU2025217289A patent/AU2025217289A1/en active Pending
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