JP2022521278A5 - - Google Patents
Info
- Publication number
- JP2022521278A5 JP2022521278A5 JP2021549207A JP2021549207A JP2022521278A5 JP 2022521278 A5 JP2022521278 A5 JP 2022521278A5 JP 2021549207 A JP2021549207 A JP 2021549207A JP 2021549207 A JP2021549207 A JP 2021549207A JP 2022521278 A5 JP2022521278 A5 JP 2022521278A5
- Authority
- JP
- Japan
- Prior art keywords
- domain
- chimeric antigen
- antigen receptor
- scfv
- receptor complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962808815P | 2019-02-21 | 2019-02-21 | |
| US201962808823P | 2019-02-21 | 2019-02-21 | |
| US201962808833P | 2019-02-21 | 2019-02-21 | |
| US62/808,815 | 2019-02-21 | ||
| US62/808,833 | 2019-02-21 | ||
| US62/808,823 | 2019-02-21 | ||
| PCT/US2020/019376 WO2020172643A2 (en) | 2019-02-21 | 2020-02-21 | Artificial immunosurveillance chimeric antigen receptor (ai-car) and cells expressing the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022521278A JP2022521278A (ja) | 2022-04-06 |
| JP2022521278A5 true JP2022521278A5 (https=) | 2022-12-19 |
| JP7812549B2 JP7812549B2 (ja) | 2026-02-10 |
Family
ID=72144733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021549207A Active JP7812549B2 (ja) | 2019-02-21 | 2020-02-21 | 人工免疫監視キメラ抗原受容体（ａｉ－ｃａｒ）及びそれを発現する細胞 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220185882A1 (https=) |
| EP (1) | EP3927352A4 (https=) |
| JP (1) | JP7812549B2 (https=) |
| KR (1) | KR20210132668A (https=) |
| CN (1) | CN113891718B (https=) |
| AU (1) | AU2020224160A1 (https=) |
| WO (1) | WO2020172643A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3773918A4 (en) | 2019-03-05 | 2022-01-05 | Nkarta, Inc. | CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY |
| WO2022272259A1 (en) * | 2021-06-23 | 2022-12-29 | H. Lee Moffitt Cancer Center And Research Institute Inc. | Car-t cell therapy for triple negative breast cancer |
| AU2022303363A1 (en) * | 2021-06-29 | 2024-01-18 | Flagship Pioneering Innovations V, Inc. | Immune cells engineered to promote thanotransmission and uses thereof |
| CN113402620B (zh) * | 2021-07-30 | 2021-12-10 | 中山大学 | 细胞因子联合嵌合抗原受体的融合蛋白及其应用 |
| CN119301157A (zh) * | 2022-05-30 | 2025-01-10 | 地中海治疗有限责任公司 | 用于癌症治疗的抗活化的Trop-2的嵌合抗原受体构建体 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201317929D0 (en) * | 2013-10-10 | 2013-11-27 | Ucl Business Plc | Chimeric antigen receptor |
| KR20170032406A (ko) * | 2014-07-15 | 2017-03-22 | 주노 쎄러퓨티크스 인코퍼레이티드 | 입양 세포 치료를 위한 조작된 세포 |
| GB201501936D0 (en) * | 2015-02-05 | 2015-03-25 | Ucl Business Plc | Signalling system |
| EP3256492A4 (en) * | 2015-02-09 | 2018-07-11 | University of Florida Research Foundation, Inc. | Bi-specific chimeric antigen receptor and uses thereof |
| WO2016127257A1 (en) * | 2015-02-12 | 2016-08-18 | University Health Network | Chimeric antigen receptors |
| US10738116B2 (en) * | 2015-03-19 | 2020-08-11 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Dual specific anti-CD22-anti-CD19 chimeric antigen receptors |
| GB201504840D0 (en) * | 2015-03-23 | 2015-05-06 | Ucl Business Plc | Chimeric antigen receptor |
| US10508143B1 (en) * | 2015-10-30 | 2019-12-17 | Aleta Biotherapeutics Inc. | Compositions and methods for treatment of cancer |
| BR112018008442A2 (pt) * | 2015-11-05 | 2018-11-06 | Juno Therapeutics Inc | receptores quiméricos contendo domínios induto-res de traf e composições e métodos relacionados |
| IL299616A (en) * | 2016-01-08 | 2023-03-01 | Univ California | Conditionally active heterodimeric polypeptides and methods of using them |
| CN113817059B (zh) * | 2016-01-09 | 2024-03-08 | 嘉立医疗科技(广州)有限公司 | 用于癌症治疗的钙粘蛋白-17特异性抗体和细胞毒性细胞 |
| GB201610515D0 (en) * | 2016-06-16 | 2016-08-03 | Autolus Ltd | Cell |
| KR20230167769A (ko) * | 2016-08-26 | 2023-12-11 | 베이롤 칼리지 오브 메드신 | 세포 치료요법을 위한 항상성 활성 사이토킨 수용체 |
| KR102746901B1 (ko) * | 2017-03-03 | 2024-12-26 | 옵시디안 테라퓨틱스, 인크. | Cd19 조성물 및 면역요법을 위한 방법 |
| CN114502188B (zh) * | 2019-02-21 | 2025-04-04 | 艾贝乐医药科技有限公司 | 人工免疫监视嵌合抗原受体及其表达细胞 |
-
2020
- 2020-02-21 JP JP2021549207A patent/JP7812549B2/ja active Active
- 2020-02-21 EP EP20758532.4A patent/EP3927352A4/en active Pending
- 2020-02-21 KR KR1020217028509A patent/KR20210132668A/ko not_active Withdrawn
- 2020-02-21 AU AU2020224160A patent/AU2020224160A1/en not_active Abandoned
- 2020-02-21 CN CN202080015256.3A patent/CN113891718B/zh active Active
- 2020-02-21 WO PCT/US2020/019376 patent/WO2020172643A2/en not_active Ceased
- 2020-02-21 US US17/432,922 patent/US20220185882A1/en not_active Abandoned
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