KR20210132668A - 인공 면역감시 키메라 항원 수용체(ai-car) 및 이를 발현하는 세포 - Google Patents

인공 면역감시 키메라 항원 수용체(ai-car) 및 이를 발현하는 세포 Download PDF

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KR20210132668A
KR20210132668A KR1020217028509A KR20217028509A KR20210132668A KR 20210132668 A KR20210132668 A KR 20210132668A KR 1020217028509 A KR1020217028509 A KR 1020217028509A KR 20217028509 A KR20217028509 A KR 20217028509A KR 20210132668 A KR20210132668 A KR 20210132668A
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ala
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도널드 이. 스톤튼
존 엠. 룩
존 엠. 할란
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아르벨 리미티드
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
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    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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KR1020217028509A 2019-02-21 2020-02-21 인공 면역감시 키메라 항원 수용체(ai-car) 및 이를 발현하는 세포 Withdrawn KR20210132668A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962808815P 2019-02-21 2019-02-21
US201962808823P 2019-02-21 2019-02-21
US201962808833P 2019-02-21 2019-02-21
US62/808,815 2019-02-21
US62/808,833 2019-02-21
US62/808,823 2019-02-21
PCT/US2020/019376 WO2020172643A2 (en) 2019-02-21 2020-02-21 Artificial immunosurveillance chimeric antigen receptor (ai-car) and cells expressing the same

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KR20210132668A true KR20210132668A (ko) 2021-11-04

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KR1020217028509A Withdrawn KR20210132668A (ko) 2019-02-21 2020-02-21 인공 면역감시 키메라 항원 수용체(ai-car) 및 이를 발현하는 세포

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US (1) US20220185882A1 (https=)
EP (1) EP3927352A4 (https=)
JP (1) JP7812549B2 (https=)
KR (1) KR20210132668A (https=)
CN (1) CN113891718B (https=)
AU (1) AU2020224160A1 (https=)
WO (1) WO2020172643A2 (https=)

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EP3773918A4 (en) 2019-03-05 2022-01-05 Nkarta, Inc. CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY
WO2022272259A1 (en) * 2021-06-23 2022-12-29 H. Lee Moffitt Cancer Center And Research Institute Inc. Car-t cell therapy for triple negative breast cancer
AU2022303363A1 (en) * 2021-06-29 2024-01-18 Flagship Pioneering Innovations V, Inc. Immune cells engineered to promote thanotransmission and uses thereof
CN113402620B (zh) * 2021-07-30 2021-12-10 中山大学 细胞因子联合嵌合抗原受体的融合蛋白及其应用
CN119301157A (zh) * 2022-05-30 2025-01-10 地中海治疗有限责任公司 用于癌症治疗的抗活化的Trop-2的嵌合抗原受体构建体

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GB201317929D0 (en) * 2013-10-10 2013-11-27 Ucl Business Plc Chimeric antigen receptor
KR20170032406A (ko) * 2014-07-15 2017-03-22 주노 쎄러퓨티크스 인코퍼레이티드 입양 세포 치료를 위한 조작된 세포
GB201501936D0 (en) * 2015-02-05 2015-03-25 Ucl Business Plc Signalling system
EP3256492A4 (en) * 2015-02-09 2018-07-11 University of Florida Research Foundation, Inc. Bi-specific chimeric antigen receptor and uses thereof
WO2016127257A1 (en) * 2015-02-12 2016-08-18 University Health Network Chimeric antigen receptors
US10738116B2 (en) * 2015-03-19 2020-08-11 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Dual specific anti-CD22-anti-CD19 chimeric antigen receptors
GB201504840D0 (en) * 2015-03-23 2015-05-06 Ucl Business Plc Chimeric antigen receptor
US10508143B1 (en) * 2015-10-30 2019-12-17 Aleta Biotherapeutics Inc. Compositions and methods for treatment of cancer
BR112018008442A2 (pt) * 2015-11-05 2018-11-06 Juno Therapeutics Inc receptores quiméricos contendo domínios induto-res de traf e composições e métodos relacionados
IL299616A (en) * 2016-01-08 2023-03-01 Univ California Conditionally active heterodimeric polypeptides and methods of using them
CN113817059B (zh) * 2016-01-09 2024-03-08 嘉立医疗科技(广州)有限公司 用于癌症治疗的钙粘蛋白-17特异性抗体和细胞毒性细胞
GB201610515D0 (en) * 2016-06-16 2016-08-03 Autolus Ltd Cell
KR20230167769A (ko) * 2016-08-26 2023-12-11 베이롤 칼리지 오브 메드신 세포 치료요법을 위한 항상성 활성 사이토킨 수용체
KR102746901B1 (ko) * 2017-03-03 2024-12-26 옵시디안 테라퓨틱스, 인크. Cd19 조성물 및 면역요법을 위한 방법
CN114502188B (zh) * 2019-02-21 2025-04-04 艾贝乐医药科技有限公司 人工免疫监视嵌合抗原受体及其表达细胞

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CN113891718A (zh) 2022-01-04
CN113891718B (zh) 2025-01-28
AU2020224160A1 (en) 2021-08-26
US20220185882A1 (en) 2022-06-16
EP3927352A2 (en) 2021-12-29
WO2020172643A3 (en) 2020-11-12
JP2022521278A (ja) 2022-04-06
JP7812549B2 (ja) 2026-02-10
EP3927352A4 (en) 2023-06-14
WO2020172643A2 (en) 2020-08-27

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