JP2022517618A5 - - Google Patents

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Publication number
JP2022517618A5
JP2022517618A5 JP2021541017A JP2021541017A JP2022517618A5 JP 2022517618 A5 JP2022517618 A5 JP 2022517618A5 JP 2021541017 A JP2021541017 A JP 2021541017A JP 2021541017 A JP2021541017 A JP 2021541017A JP 2022517618 A5 JP2022517618 A5 JP 2022517618A5
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JP
Japan
Prior art keywords
cells
cell
hematopoietic stem
genetically modified
progenitor
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JP2021541017A
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English (en)
Japanese (ja)
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JP2022517618A (ja
JP7784707B2 (ja
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Priority claimed from PCT/US2020/013887 external-priority patent/WO2020150478A1/en
Publication of JP2022517618A publication Critical patent/JP2022517618A/ja
Publication of JP2022517618A5 publication Critical patent/JP2022517618A5/ja
Priority to JP2025202676A priority Critical patent/JP2026035683A/ja
Application granted granted Critical
Publication of JP7784707B2 publication Critical patent/JP7784707B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021541017A 2019-01-16 2020-01-16 系統特異的抗原の阻害のための組成物および方法 Active JP7784707B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025202676A JP2026035683A (ja) 2019-01-16 2025-11-25 系統特異的抗原の阻害のための組成物および方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962793210P 2019-01-16 2019-01-16
US62/793,210 2019-01-16
US201962852573P 2019-05-24 2019-05-24
US62/852,573 2019-05-24
PCT/US2020/013887 WO2020150478A1 (en) 2019-01-16 2020-01-16 Compositions and methods for inhibition of lineage specific antigens

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025202676A Division JP2026035683A (ja) 2019-01-16 2025-11-25 系統特異的抗原の阻害のための組成物および方法

Publications (3)

Publication Number Publication Date
JP2022517618A JP2022517618A (ja) 2022-03-09
JP2022517618A5 true JP2022517618A5 (https=) 2023-01-25
JP7784707B2 JP7784707B2 (ja) 2025-12-12

Family

ID=71613437

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021541017A Active JP7784707B2 (ja) 2019-01-16 2020-01-16 系統特異的抗原の阻害のための組成物および方法
JP2025202676A Pending JP2026035683A (ja) 2019-01-16 2025-11-25 系統特異的抗原の阻害のための組成物および方法

Family Applications After (1)

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JP2025202676A Pending JP2026035683A (ja) 2019-01-16 2025-11-25 系統特異的抗原の阻害のための組成物および方法

Country Status (12)

Country Link
US (1) US20210260130A1 (https=)
EP (1) EP3911338A4 (https=)
JP (2) JP7784707B2 (https=)
KR (1) KR20210129048A (https=)
CN (1) CN113474452A (https=)
AU (1) AU2020209218A1 (https=)
BR (1) BR112021014010A2 (https=)
CA (1) CA3126677A1 (https=)
IL (1) IL284853A (https=)
MX (1) MX2021008490A (https=)
SG (1) SG11202107639UA (https=)
WO (1) WO2020150478A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2019130504A (ru) 2017-02-28 2021-03-30 Вор Байофарма, Инк. Композиции и способы ингибирования линиеспецифических белков
CA3110837A1 (en) 2018-08-28 2020-03-05 Vor Biopharma Inc. Genetically engineered hematopoietic stem cells and uses thereof
AU2020280103A1 (en) * 2019-05-23 2021-12-23 Vor Biopharma Inc. Compositions and methods for CD33 modification
AU2020338011A1 (en) * 2019-08-28 2022-03-10 Vor Biopharma Inc. Compositions and methods for CLL1 modification
WO2022047168A1 (en) * 2020-08-28 2022-03-03 Vor Biopharma Inc. Compositions and methods for cll1 modification
WO2022093983A1 (en) * 2020-10-27 2022-05-05 Vor Biopharma, Inc. Compositions and methods for treating hematopoietic malignancy
CN120249215A (zh) * 2021-04-27 2025-07-04 上海驯鹿生物技术有限公司 一种基因编辑的造血干细胞及其与car-t细胞的联合应用
WO2023283585A2 (en) 2021-07-06 2023-01-12 Vor Biopharma Inc. Inhibitor oligonucleotides and methods of use thereof
AU2022324093A1 (en) 2021-08-02 2024-02-08 Vor Biopharma Inc. Compositions and methods for gene modification
WO2024015925A2 (en) 2022-07-13 2024-01-18 Vor Biopharma Inc. Compositions and methods for artificial protospacer adjacent motif (pam) generation
WO2024073751A1 (en) 2022-09-29 2024-04-04 Vor Biopharma Inc. Methods and compositions for gene modification and enrichment
WO2025030010A1 (en) 2023-08-01 2025-02-06 Vor Biopharma Inc. Compositions comprising genetically engineered hematopoietic stem cells and methods of use thereof
BG113932A (bg) * 2024-07-19 2026-01-30 Медицински университет – Пловдив Панели и китове от реагенти за измерване на минимална резидуална болест при детска в-клетъчна прекурсорна остра лимфобластна левкемия чрез имунофенотипизация

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106795221B (zh) * 2014-04-03 2022-06-07 塞勒克提斯公司 用于癌症免疫治疗的cd33特异性嵌合抗原受体
CN108064176A (zh) * 2015-04-22 2018-05-22 库瑞瓦格股份公司 用于治疗肿瘤疾病的含有rna的组合物
CA2986310A1 (en) * 2015-05-11 2016-11-17 Editas Medicine, Inc. Optimized crispr/cas9 systems and methods for gene editing in stem cells
AU2016337525B2 (en) * 2015-10-16 2022-01-20 The Trustees Of Columbia University In The City Of New York Compositions and methods for inhibition of lineage specific antigens
KR20180118111A (ko) * 2015-12-23 2018-10-30 크리스퍼 테라퓨틱스 아게 근위축성 측색 경화증 및/또는 전두측두엽 퇴행의 치료 물질 및 방법
EP3585895A1 (en) * 2017-02-22 2020-01-01 CRISPR Therapeutics AG Compositions and methods for gene editing
US11718659B2 (en) * 2017-08-28 2023-08-08 The Trustees Of Columbia University In The City Of New York CD33 exon 2 deficient donor stem cells for use with CD33 targeting agents

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