JP2022516496A5 - - Google Patents

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Publication number
JP2022516496A5
JP2022516496A5 JP2021537987A JP2021537987A JP2022516496A5 JP 2022516496 A5 JP2022516496 A5 JP 2022516496A5 JP 2021537987 A JP2021537987 A JP 2021537987A JP 2021537987 A JP2021537987 A JP 2021537987A JP 2022516496 A5 JP2022516496 A5 JP 2022516496A5
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JP
Japan
Prior art keywords
domain
linker
chimeric receptor
receptor polypeptide
tcr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021537987A
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English (en)
Japanese (ja)
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JP2022516496A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/CN2020/071947 external-priority patent/WO2020147708A1/en
Publication of JP2022516496A publication Critical patent/JP2022516496A/ja
Publication of JP2022516496A5 publication Critical patent/JP2022516496A5/ja
Pending legal-status Critical Current

Links

JP2021537987A 2019-01-14 2020-01-14 キメラ受容体ポリペプチド及びその使用 Pending JP2022516496A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2019071609 2019-01-14
CNPCT/CN2019/071609 2019-01-14
PCT/CN2020/071947 WO2020147708A1 (en) 2019-01-14 2020-01-14 Chimeric receptor polypeptides and uses thereof

Publications (2)

Publication Number Publication Date
JP2022516496A JP2022516496A (ja) 2022-02-28
JP2022516496A5 true JP2022516496A5 (https=) 2023-01-19

Family

ID=71614406

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021537987A Pending JP2022516496A (ja) 2019-01-14 2020-01-14 キメラ受容体ポリペプチド及びその使用

Country Status (9)

Country Link
US (1) US20230192805A1 (https=)
EP (1) EP3911370A4 (https=)
JP (1) JP2022516496A (https=)
KR (1) KR20210116478A (https=)
CN (1) CN113164626A (https=)
AU (1) AU2020208110A1 (https=)
CA (1) CA3126422A1 (https=)
SG (1) SG11202106257WA (https=)
WO (1) WO2020147708A1 (https=)

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KR20210104772A (ko) 2018-12-14 2021-08-25 블루버드 바이오, 인코포레이티드. 이량체화제로 조절된 면역수용체 복합체
WO2022228579A1 (en) * 2021-04-30 2022-11-03 Nanjing Legend Biotech Co., Ltd. Chimeric antigen receptors targeting gpc3 and methods of use thereof
CN117897411A (zh) * 2021-06-30 2024-04-16 华夏英泰(北京)生物技术有限公司 一种多靶点合成t细胞受体抗原/抗体受体及其应用
JP2024525727A (ja) * 2021-07-14 2024-07-12 2セブンティ バイオ インコーポレイテッド 抗体由来の結合ドメインに融合した操作されたt細胞受容体
WO2023164698A2 (en) * 2022-02-27 2023-08-31 Health Research, Inc. FOLATE RECEPTOR ALPHA -TARGETING BI-SPECIFIC T CELL ENGAGERS (BiTEs) AND USES THEREOF
CN114560948B (zh) * 2022-03-07 2023-05-23 中国人民解放军空军军医大学 一种嵌合抗原受体、car-t细胞及其应用
CN114573712B (zh) * 2022-03-07 2023-05-12 中国人民解放军空军军医大学 一种嵌合抗原受体、car-t细胞及其应用
CN114560949B (zh) * 2022-03-07 2023-09-26 中国人民解放军空军军医大学 一种具有增强car-t细胞抗肿瘤能力的嵌合抗原受体、d-car-t细胞及其应用
CN119032110A (zh) * 2022-04-07 2024-11-26 恺兴生命科技(上海)有限公司 嵌合多肽及其应用
AR130387A1 (es) * 2022-09-08 2024-12-04 Hoffmann La Roche Receptores de linfocitos t recombinantes
WO2024100136A1 (en) * 2022-11-08 2024-05-16 Gadeta B.V. Novel method for obtaining gamma t-cell (or delta t-cell) receptor chains (or gamma delta t-cell receptors) or fragments thereof that mediate an anti-tumour or an anti-infective response
CN120435501A (zh) * 2022-12-30 2025-08-05 上药生物治疗(香港)有限公司 细胞原位分泌抗体及其用途
CN117074674B (zh) * 2023-03-23 2024-01-23 武汉勖瑞生物科技有限责任公司 检测N-乙酰-β-D氨基葡萄糖苷酶的胶体金试纸及其制备方法
WO2024206992A2 (en) * 2023-03-30 2024-10-03 Yale University Universal antibody receptors, guar-t cells and therapeutic use thereof

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
GB0908613D0 (en) * 2009-05-20 2009-06-24 Immunocore Ltd T Cell Reseptors
LT3030581T (lt) * 2013-08-07 2021-05-25 Affimed Gmbh Antikūno surišimo vietos specifiškos egfrviii
US9212225B1 (en) * 2014-07-01 2015-12-15 Amphivena Therapeutics, Inc. Bispecific CD33 and CD3 binding proteins
CA2970924A1 (en) * 2014-10-31 2016-05-06 H. Lee Moffitt Cancer Center And Research Institute, Inc. Tetravalent tlr9 bispecific antibody
HRP20191873T1 (hr) * 2014-12-12 2020-01-24 Bluebird Bio, Inc. Kimerni antigenski receptori
PL3298033T5 (pl) * 2015-05-18 2023-10-30 TCR2 Therapeutics Inc. Kompozycje i zastosowania medyczne do reprogramowania TCR z zastosowaniem białek fuzyjnych
GB201522592D0 (en) * 2015-12-22 2016-02-03 Immunocore Ltd T cell receptors
GB201604953D0 (en) * 2016-03-23 2016-05-04 Immunocore Ltd T cell receptors
CN105777911B (zh) * 2016-04-12 2019-07-02 上海优卡迪生物医药科技有限公司 抗bcma嵌合抗原受体、编码基因、重组表达载体及其构建方法和应用
CN110582509A (zh) * 2017-01-31 2019-12-17 诺华股份有限公司 使用具有多特异性的嵌合t细胞受体蛋白治疗癌症
JP7538601B2 (ja) * 2017-04-26 2024-08-22 ユーリカ セラピューティックス, インコーポレイテッド キメラ活性化受容体及びキメラ刺激受容体を発現する細胞並びにその使用

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