JP2022514956A5 - - Google Patents
Info
- Publication number
- JP2022514956A5 JP2022514956A5 JP2021536372A JP2021536372A JP2022514956A5 JP 2022514956 A5 JP2022514956 A5 JP 2022514956A5 JP 2021536372 A JP2021536372 A JP 2021536372A JP 2021536372 A JP2021536372 A JP 2021536372A JP 2022514956 A5 JP2022514956 A5 JP 2022514956A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- polymer nanocapsule
- alkyl group
- amino
- positively charged
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862784503P | 2018-12-23 | 2018-12-23 | |
| US62/784,503 | 2018-12-23 | ||
| PCT/US2019/068259 WO2020139807A2 (en) | 2018-12-23 | 2019-12-23 | Nanocapsules for the delivery of cell modulating agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022514956A JP2022514956A (ja) | 2022-02-16 |
| JP2022514956A5 true JP2022514956A5 (https=) | 2023-01-05 |
| JP7795356B2 JP7795356B2 (ja) | 2026-01-07 |
Family
ID=69326704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021536372A Active JP7795356B2 (ja) | 2018-12-23 | 2019-12-23 | 細胞調節剤の送達のためのナノカプセル |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20210322331A1 (https=) |
| EP (1) | EP3898978A2 (https=) |
| JP (1) | JP7795356B2 (https=) |
| CN (1) | CN113544270A (https=) |
| AU (1) | AU2019414331B2 (https=) |
| WO (1) | WO2020139807A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115012221B (zh) * | 2021-03-05 | 2023-08-08 | 北京化工大学 | 一种控制干细胞分化的纳米纤维材料及其制备方法和用途 |
| CN112972703B (zh) * | 2021-03-10 | 2023-04-28 | 河南大学 | 基因编辑纳米胶囊及其制备方法与应用 |
| CN113201499A (zh) * | 2021-04-22 | 2021-08-03 | 广州医科大学附属第三医院(广州重症孕产妇救治中心、广州柔济医院) | Hbb基因cd17突变细胞及其制备方法与应用 |
| CN117460518A (zh) * | 2021-04-30 | 2024-01-26 | 宾夕法尼亚大学理事会 | Cd-90靶向的脂质纳米颗粒 |
| WO2024220878A1 (en) * | 2023-04-20 | 2024-10-24 | Purdue Research Foundation | Delivery of nucleic acids using a targeted peptide carrier system |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5958928A (en) | 1995-03-27 | 1999-09-28 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical agents containing methotrexate derivative |
| WO2007098089A2 (en) | 2006-02-17 | 2007-08-30 | Novacea, Inc. | Treatment of hyperproliferative diseases with methotrexate n-oxide and analogs |
| SG174287A1 (en) | 2009-03-09 | 2011-10-28 | Univ California | Single protein nanocapsules for protein delivery with long-term effect |
| US20140154269A1 (en) * | 2011-04-26 | 2014-06-05 | The Methodist Hospital Research Institute | Targeted nanovectors and their use for treatment of brain tumors |
| CA2907095C (en) | 2012-03-16 | 2020-11-03 | The Regents Of The University Of California | A novel rnai molecule delivery platform based on single-sirna and shrna nanocapsules |
| CN105683376A (zh) | 2013-05-15 | 2016-06-15 | 桑格摩生物科学股份有限公司 | 用于治疗遗传病状的方法和组合物 |
| EP3470089A1 (en) * | 2013-12-12 | 2019-04-17 | The Broad Institute Inc. | Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using particle delivery components |
| JP6712948B2 (ja) * | 2013-12-12 | 2020-06-24 | ザ・ブロード・インスティテュート・インコーポレイテッド | 組成物、及びヌクレオチドリピート障害におけるcrispr−cas系の使用方法 |
| JP2018509387A (ja) | 2015-01-21 | 2018-04-05 | フェーズアールエックス インコーポレイテッド | 細胞に治療および診断剤を送達するための方法、組成物、ならびにシステム |
| US11279928B2 (en) * | 2015-06-29 | 2022-03-22 | Massachusetts Institute Of Technology | Compositions comprising nucleic acids and methods of using the same |
| US20180237800A1 (en) * | 2015-09-21 | 2018-08-23 | The Regents Of The University Of California | Compositions and methods for target nucleic acid modification |
| EP3463428A4 (en) * | 2016-05-24 | 2020-01-08 | The Regents of the University of California | GROWTH FACTOR NANO CAPSULES WITH TUNABLE RELEASE FOR BONE REGENERATION |
| WO2017223398A1 (en) * | 2016-06-23 | 2017-12-28 | University Of Massachusetts | Polymeric nanoparticles and derivatives thereof for nucleic acid binding and delivery |
| US20210113466A1 (en) * | 2017-03-16 | 2021-04-22 | Children's Medical Center Corporation | Non-viral, non-cationic nanoparticles and uses thereof |
| CA3074202A1 (en) * | 2017-08-28 | 2019-03-07 | Wisconsin Alumni Research Foundation | Nanocapsules for delivering ribonucleoproteins |
-
2019
- 2019-12-23 CN CN201980092149.8A patent/CN113544270A/zh active Pending
- 2019-12-23 JP JP2021536372A patent/JP7795356B2/ja active Active
- 2019-12-23 AU AU2019414331A patent/AU2019414331B2/en active Active
- 2019-12-23 WO PCT/US2019/068259 patent/WO2020139807A2/en not_active Ceased
- 2019-12-23 EP EP19842997.9A patent/EP3898978A2/en active Pending
-
2021
- 2021-06-21 US US17/353,440 patent/US20210322331A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022514956A5 (https=) | ||
| JP5021160B2 (ja) | pH−感受性ポリマー | |
| US20210121411A1 (en) | Lipid nanoparticle compositions for delivery of mrna and long nucleic acids | |
| Pan et al. | Redox/pH dual stimuli-responsive biodegradable nanohydrogels with varying responses to dithiothreitol and glutathione for controlled drug release | |
| ES2672153T3 (es) | Composiciones farmcéuticas que comprenden poli(beta-amino-ésteres) biodegradables | |
| Neu et al. | Bioreversibly crosslinked polyplexes of PEI and high molecular weight PEG show extended circulation times in vivo | |
| JP7038054B2 (ja) | 粘膜付着型薬物送達のためのミセル | |
| CN119546278A (zh) | 两性离子在眼用局部乳膏组合物和制剂中的新应用 | |
| WO2014066912A1 (en) | Polymeric nanoparticles | |
| US20140199244A1 (en) | Controlled release system | |
| JP2008518949A (ja) | リン酸塩結合剤のための1日1回製剤 | |
| Cavallaro et al. | Synthesis and characterization of polyaspartamide copolymers obtained by ATRP for nucleic acid delivery | |
| JP7093975B2 (ja) | 両性イオンポリマー、その製造方法、及び両性イオンポリマーを含むタンパク質安定化剤 | |
| Laaser et al. | Architecture-Dependent Stabilization of Polyelectrolyte Complexes between Polyanions and Cationic Triblock Terpolymer Micelles | |
| US20250108125A1 (en) | Polymer nanoparticle compositions for non-viral gene delivery to the central nervous system | |
| Gu et al. | Biodistribution of PNIPAM-coated nanostructures synthesized by the TDMT method | |
| JP6205364B2 (ja) | 薬物徐放性眼用レンズ及びその製造方法 | |
| Xiong et al. | Biotin-Triggered Release of Poly (ethylene glycol)− Avidin from Biotinylated Polyethylenimine Enhances in Vitro Gene Expression | |
| Carr et al. | Mediating high levels of gene transfer without cytotoxicity via hydrolytic cationic ester polymers | |
| JP2010504318A5 (https=) | ||
| CA3232690A1 (en) | Multi-motif dendrons and their supramolecular structures and uses thereof | |
| RU2005100840A (ru) | Фторсилоксановые матриксные системы доставки лекарств с регулируемой диффузией | |
| CN104027816B (zh) | 一种可去聚乙二醇化的共装载阿霉素和siRNA载体及其合成方法 | |
| WO2025250979A1 (en) | Polymer nanoparticle compositions for non-viral gene delivery | |
| JP6654057B2 (ja) | 局所麻酔薬を含有するポリイオンコンプレックスを有効成分とする局所疼痛制御用組成物 |