JP2022514835A5 - - Google Patents
Info
- Publication number
- JP2022514835A5 JP2022514835A5 JP2021534266A JP2021534266A JP2022514835A5 JP 2022514835 A5 JP2022514835 A5 JP 2022514835A5 JP 2021534266 A JP2021534266 A JP 2021534266A JP 2021534266 A JP2021534266 A JP 2021534266A JP 2022514835 A5 JP2022514835 A5 JP 2022514835A5
- Authority
- JP
- Japan
- Prior art keywords
- cysteine
- insulin
- acid
- composition according
- glutamic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024147410A JP2024178193A (ja) | 2018-12-21 | 2024-08-29 | インスリン及びグルカゴンを含む薬学組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2018-0167798 | 2018-12-21 | ||
| KR20180167798 | 2018-12-21 | ||
| PCT/KR2019/018320 WO2020130751A1 (ko) | 2018-12-21 | 2019-12-23 | 인슐린 및 글루카곤을 포함하는 약학 조성물 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024147410A Division JP2024178193A (ja) | 2018-12-21 | 2024-08-29 | インスリン及びグルカゴンを含む薬学組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022514835A JP2022514835A (ja) | 2022-02-16 |
| JP2022514835A5 true JP2022514835A5 (enExample) | 2023-01-06 |
Family
ID=71102651
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021534266A Pending JP2022514835A (ja) | 2018-12-21 | 2019-12-23 | インスリン及びグルカゴンを含む薬学組成物 |
| JP2024147410A Pending JP2024178193A (ja) | 2018-12-21 | 2024-08-29 | インスリン及びグルカゴンを含む薬学組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024147410A Pending JP2024178193A (ja) | 2018-12-21 | 2024-08-29 | インスリン及びグルカゴンを含む薬学組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220064248A1 (enExample) |
| EP (1) | EP3900734A4 (enExample) |
| JP (2) | JP2022514835A (enExample) |
| KR (1) | KR20200078414A (enExample) |
| CN (1) | CN113365651A (enExample) |
| AU (1) | AU2019405389B2 (enExample) |
| BR (1) | BR112021011557A2 (enExample) |
| CA (1) | CA3124340A1 (enExample) |
| MX (1) | MX2021007124A (enExample) |
| WO (1) | WO2020130751A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020130749A1 (ko) * | 2018-12-21 | 2020-06-25 | 한미약품 주식회사 | 글루카곤, glp-1 및 gip 수용체 모두에 활성을 갖는 삼중 활성체 및 인슐린을 포함하는 약학 조성물 |
| BR112023000515A2 (pt) * | 2020-07-15 | 2023-03-21 | Hanmi Pharm Ind Co Ltd | Composição farmacêutica e seu uso |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
| CA2249195A1 (en) | 1996-03-18 | 1997-09-25 | Board Of Regents, The University Of Texas System | Immunoglobin-like domains with increased half lives |
| NZ541365A (en) * | 2002-12-27 | 2009-09-25 | Diobex Inc | Compositions and methods for the prevention and control of insulin-induced hypoglycemia |
| AR081066A1 (es) * | 2010-04-02 | 2012-06-06 | Hanmi Holdings Co Ltd | Conjugado de insulina donde se usa un fragmento de inmunoglobulina |
| EA201390796A1 (ru) * | 2011-01-20 | 2014-07-30 | Зилэнд Фарма А/С | Применение ацилированного аналога глюкагона |
| KR20140106452A (ko) | 2013-02-26 | 2014-09-03 | 한미약품 주식회사 | 신규한 인슐린 아날로그 및 이의 용도 |
| TWI684458B (zh) * | 2014-05-30 | 2020-02-11 | 南韓商韓美藥品股份有限公司 | 包含胰島素及ｇｌｐ-１/昇糖素雙重促效劑之治療糖尿病之組成物 |
| EP3151855B1 (en) | 2014-06-08 | 2021-11-24 | REMD Biotherapeutics, Inc. | Methods for treating type 1 diabetes using glucagon receptor antagonistic antibodies |
| KR102291020B1 (ko) | 2014-12-30 | 2021-08-20 | 한미약품 주식회사 | 안정성이 증가된 글루카곤 유도체 |
| FI3322437T3 (fi) * | 2015-06-30 | 2024-02-20 | Hanmi Pharmaceutical Co Ltd | Glukagonijohdannainen ja sen pitkävaikutteisen konjugaatin käsittävä koostumus |
| UY36870A (es) | 2015-08-28 | 2017-03-31 | Hanmi Pharm Ind Co Ltd | Análogos de insulina novedosos |
| CN108136276B (zh) * | 2015-09-24 | 2023-02-28 | 韩美药品株式会社 | 通过使用免疫球蛋白片段的特异性位点进行连接的蛋白质复合物 |
| TW201718629A (zh) * | 2015-09-25 | 2017-06-01 | 韓美藥品股份有限公司 | 包含多個生理多肽及免疫球蛋白Ｆｃ區之蛋白質接合物 |
| CN122440793A (zh) | 2016-06-29 | 2026-07-24 | 韩美药品株式会社 | 胰高血糖素衍生物、其缀合物、包含其的组合物、和其治疗用途 |
| EP3578204A4 (en) * | 2017-02-03 | 2021-01-06 | Hanmi Pharm. Co., Ltd. | CONJUGATE MADE FROM BIOACTIVE MATERIAL WITH INCREASED RESISTANCE AND USE OF IT |
| US11357829B2 (en) * | 2017-02-03 | 2022-06-14 | Vanderbilt University | Systems, compositions and methods for treating diabetes |
| GB201710822D0 (en) * | 2017-07-05 | 2017-08-16 | Zealand Pharma As | Methods and medical uses relating to the treatment of hypoglycaemia |
-
2019
- 2019-12-23 WO PCT/KR2019/018320 patent/WO2020130751A1/ko not_active Ceased
- 2019-12-23 KR KR1020190173205A patent/KR20200078414A/ko not_active Ceased
- 2019-12-23 EP EP19897547.6A patent/EP3900734A4/en active Pending
- 2019-12-23 BR BR112021011557-9A patent/BR112021011557A2/pt unknown
- 2019-12-23 CN CN201980090567.3A patent/CN113365651A/zh active Pending
- 2019-12-23 AU AU2019405389A patent/AU2019405389B2/en active Active
- 2019-12-23 US US17/415,474 patent/US20220064248A1/en active Pending
- 2019-12-23 CA CA3124340A patent/CA3124340A1/en active Pending
- 2019-12-23 JP JP2021534266A patent/JP2022514835A/ja active Pending
- 2019-12-23 MX MX2021007124A patent/MX2021007124A/es unknown
-
2024
- 2024-08-29 JP JP2024147410A patent/JP2024178193A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7322105B2 (ja) | 免疫グロブリンＦｃフラグメント結合を用いたタンパク質及びペプチドの溶解度を改善する方法 | |
| JP2018526333A5 (enExample) | ||
| JP2019504055A5 (enExample) | ||
| CN107106660B (zh) | 长效glp-1/胰高血糖素受体双激动剂对于治疗非酒精性脂肪肝疾病的应用 | |
| TWI648401B (zh) | 生長分化因子１５（ｇｄｆ－１５）構築體 | |
| JP6749845B2 (ja) | インスリン及びｇｌｐ−１／グルカゴン二重アゴニストを含む糖尿病治療用組成物 | |
| JP2019524675A5 (enExample) | ||
| BRPI0916326A2 (pt) | complexo polipeptídico compreendendo polímero não-peptidil com três extremidades funcionais | |
| RU2009129953A (ru) | Инсулинотропный комплекс, в котором использован фрагмент иммуноглобулина | |
| JP2022551282A5 (enExample) | ||
| EA038524B1 (ru) | Длительно действующий конъюгат тройного агониста рецепторов глюкагона/glp 1/gip | |
| CN107810202A (zh) | 长效胰岛素或胰岛素类似物复合物 | |
| RU2015138536A (ru) | Новый аналог инсулина и его применение | |
| RU2016147505A (ru) | Конъюгат, содержащий оксинтомодулин и фрагмент иммуноглобулина, и его применение | |
| JP2016519569A5 (enExample) | ||
| CN108064230A (zh) | 使重组抗体分子单体化的方法 | |
| JP2024178193A (ja) | インスリン及びグルカゴンを含む薬学組成物 | |
| JP2024512895A5 (enExample) | ||
| RU2021116078A (ru) | Фармацевтическая композиция, содержащая инсулин и глюкагон | |
| IL293745A (en) | Bifunctional molecules containing il-7 variant | |
| IL305549A (en) | Pharmaceutical composition for the prevention or treatment of chronic kidney disease including a glucagon derivative | |
| RU2019131593A (ru) | Комплекс аналога инсулина со сниженной аффинностью к инсулиновому рецептору и его применение | |
| CN114984231B (zh) | 稳定性制剂及其制备方法 | |
| RU2847194C1 (ru) | Жидкая композиция длительно действующего конъюгата тройного агониста глюкагона, GLP-1 И GIP | |
| NZ750267B2 (en) | Glucagon derivative, conjugate thereof, composition comprising same and therapeutic use thereof |