JP2022514348A5 - - Google Patents
Info
- Publication number
- JP2022514348A5 JP2022514348A5 JP2021535547A JP2021535547A JP2022514348A5 JP 2022514348 A5 JP2022514348 A5 JP 2022514348A5 JP 2021535547 A JP2021535547 A JP 2021535547A JP 2021535547 A JP2021535547 A JP 2021535547A JP 2022514348 A5 JP2022514348 A5 JP 2022514348A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- compound according
- antibody
- derived
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024163811A JP2024178320A (ja) | 2018-12-21 | 2024-09-20 | チオール多重リンカーを有するａｄｃ |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862783707P | 2018-12-21 | 2018-12-21 | |
| US201862783582P | 2018-12-21 | 2018-12-21 | |
| US62/783,582 | 2018-12-21 | ||
| US62/783,707 | 2018-12-21 | ||
| PCT/US2019/068178 WO2020132655A1 (en) | 2018-12-21 | 2019-12-20 | Adcs with thiol multiplex linkers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024163811A Division JP2024178320A (ja) | 2018-12-21 | 2024-09-20 | チオール多重リンカーを有するａｄｃ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022514348A JP2022514348A (ja) | 2022-02-10 |
| JP2022514348A5 true JP2022514348A5 (enExample) | 2022-12-20 |
Family
ID=71101991
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021535547A Ceased JP2022514348A (ja) | 2018-12-21 | 2019-12-20 | チオール多重リンカーを有するａｄｃ |
| JP2024163811A Pending JP2024178320A (ja) | 2018-12-21 | 2024-09-20 | チオール多重リンカーを有するａｄｃ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024163811A Pending JP2024178320A (ja) | 2018-12-21 | 2024-09-20 | チオール多重リンカーを有するａｄｃ |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20220040320A1 (enExample) |
| EP (1) | EP3897734A4 (enExample) |
| JP (2) | JP2022514348A (enExample) |
| KR (1) | KR20210141918A (enExample) |
| CN (1) | CN113543812A (enExample) |
| AU (1) | AU2019403552A1 (enExample) |
| CA (1) | CA3122316A1 (enExample) |
| IL (1) | IL284147A (enExample) |
| MX (1) | MX2021007548A (enExample) |
| SG (1) | SG11202106122QA (enExample) |
| TW (1) | TW202039008A (enExample) |
| WO (1) | WO2020132655A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2021251875A1 (en) * | 2020-04-10 | 2022-11-03 | Seagen Inc. | Charge variant linkers |
| TW202400266A (zh) * | 2022-05-18 | 2024-01-01 | 大陸商成都百利多特生物藥業有限責任公司 | 配體藥物偶聯物及其應用 |
| KR20250169306A (ko) | 2023-04-18 | 2025-12-02 | 아스트라제네카 아베 | 절단가능한 링커를 포함하는 접합체 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0871490T3 (da) * | 1995-12-22 | 2003-07-07 | Bristol Myers Squibb Co | Forgrenede hydrazonlinkere |
| JP2001505194A (ja) * | 1996-11-05 | 2001-04-17 | ブリストル―マイヤーズ・スクイブ・カンパニー | 分枝ペプチド・リンカー |
| DE10048417A1 (de) * | 2000-09-29 | 2002-04-11 | Roche Diagnostics Gmbh | Verbindungen mit verzweigtem Linker |
| US6821529B2 (en) * | 2001-09-05 | 2004-11-23 | Deanna Jean Nelson | Oligo(ethylene glycoll)-terminated 1,2-dithiolanes and their conjugates useful for preparing self-assembled monolayers |
| KR100889587B1 (ko) * | 2006-05-12 | 2009-03-19 | 한국생명공학연구원 | 기질표면 처리 및 특이적 단백질 고정용 링커분자, 및 그제조방법 |
| WO2008147481A1 (en) * | 2007-02-09 | 2008-12-04 | Northeastern University | Precision-guided nanoparticle systems for drug delivery |
| EP2606072A4 (en) * | 2010-08-19 | 2016-04-20 | Peg Biosciences Inc | SYNERGISTIC BIOMOLECULAR POLYMER CONJUGATES |
| BR112013007160A2 (pt) * | 2010-09-29 | 2016-06-14 | Philogen Spa | ligante tiazolidina para a conjugação de fármacos a anticorpos |
| WO2013173337A2 (en) * | 2012-05-15 | 2013-11-21 | Seattle Genetics, Inc. | Self-stabilizing linker conjugates |
| CN104640572B (zh) * | 2012-05-15 | 2018-04-27 | 索伦托医疗有限公司 | 药物偶联物，偶联方法，及其用途 |
| ES2781523T3 (es) * | 2012-07-12 | 2020-09-02 | Hangzhou Dac Biotech Co Ltd | Conjugados de moléculas de unión celular con agentes citotóxicos |
| SG11201601424PA (en) * | 2013-08-28 | 2016-03-30 | Stemcentrx Inc | Site-specific antibody conjugation methods and compositions |
| TW201511774A (zh) * | 2013-09-18 | 2015-04-01 | Iner Aec Executive Yuan | 放射性標誌之主動標靶性醫藥組合物及其用途 |
| NZ758049A (en) * | 2013-10-15 | 2024-03-22 | Seagen Inc | Pegylated drug-linkers for improved ligand-drug conjugate pharmacokinetics |
| WO2016025752A1 (en) * | 2014-08-14 | 2016-02-18 | Prolynx Llc | Reagents for thiol conjugation and conjugates formed therefrom |
| US11135307B2 (en) * | 2016-11-23 | 2021-10-05 | Mersana Therapeutics, Inc. | Peptide-containing linkers for antibody-drug conjugates |
| AU2021251875A1 (en) * | 2020-04-10 | 2022-11-03 | Seagen Inc. | Charge variant linkers |
-
2019
- 2019-12-20 AU AU2019403552A patent/AU2019403552A1/en not_active Abandoned
- 2019-12-20 WO PCT/US2019/068178 patent/WO2020132655A1/en not_active Ceased
- 2019-12-20 CN CN201980085333.XA patent/CN113543812A/zh active Pending
- 2019-12-20 KR KR1020217022058A patent/KR20210141918A/ko not_active Abandoned
- 2019-12-20 SG SG11202106122QA patent/SG11202106122QA/en unknown
- 2019-12-20 US US17/311,508 patent/US20220040320A1/en not_active Abandoned
- 2019-12-20 EP EP19900437.5A patent/EP3897734A4/en not_active Withdrawn
- 2019-12-20 MX MX2021007548A patent/MX2021007548A/es unknown
- 2019-12-20 JP JP2021535547A patent/JP2022514348A/ja not_active Ceased
- 2019-12-20 CA CA3122316A patent/CA3122316A1/en active Pending
- 2019-12-23 TW TW108147276A patent/TW202039008A/zh unknown
-
2021
- 2021-06-17 IL IL284147A patent/IL284147A/en unknown
-
2024
- 2024-09-20 JP JP2024163811A patent/JP2024178320A/ja active Pending
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