JP2022513846A5 - - Google Patents
Info
- Publication number
- JP2022513846A5 JP2022513846A5 JP2021533779A JP2021533779A JP2022513846A5 JP 2022513846 A5 JP2022513846 A5 JP 2022513846A5 JP 2021533779 A JP2021533779 A JP 2021533779A JP 2021533779 A JP2021533779 A JP 2021533779A JP 2022513846 A5 JP2022513846 A5 JP 2022513846A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- pharmaceutically acceptable
- tautomer
- stereoisomer
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862780066P | 2018-12-14 | 2018-12-14 | |
| US62/780,066 | 2018-12-14 | ||
| PCT/US2019/066201 WO2020123925A1 (en) | 2018-12-14 | 2019-12-13 | Pyrazolopyridine inhibitors of c-jun-n-terminal kinases and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022513846A JP2022513846A (ja) | 2022-02-09 |
| JP2022513846A5 true JP2022513846A5 (https=) | 2022-12-21 |
| JP7642540B2 JP7642540B2 (ja) | 2025-03-10 |
Family
ID=71077020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021533779A Active JP7642540B2 (ja) | 2018-12-14 | 2019-12-13 | Ｃ－ｊｕｎ－ｎ末キナーゼのピラゾロピリジンインヒビターおよびそれらの使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220073512A1 (https=) |
| EP (1) | EP3893879A4 (https=) |
| JP (1) | JP7642540B2 (https=) |
| CN (1) | CN113164477A (https=) |
| AU (1) | AU2019395255B2 (https=) |
| CA (1) | CA3115126A1 (https=) |
| WO (1) | WO2020123925A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011090738A2 (en) | 2009-12-29 | 2011-07-28 | Dana-Farber Cancer Institute, Inc. | Type ii raf kinase inhibitors |
| JP6854762B2 (ja) | 2014-12-23 | 2021-04-07 | ダナ−ファーバー キャンサー インスティテュート， インコーポレイテッド | サイクリン依存性キナーゼ７（ｃｄｋ７）の阻害剤 |
| USRE50776E1 (en) | 2015-03-27 | 2026-02-03 | Dana-Farber Cancer Institute, Inc. | Inhibitors of cyclin-dependent kinases |
| AU2017363307B2 (en) * | 2016-11-22 | 2021-07-29 | Dana-Farber Cancer Institute, Inc. | Inhibitors of cyclin-dependent kinase 12 (CDK12) and uses thereof |
| US12281126B2 (en) | 2018-12-28 | 2025-04-22 | Dana-Farber Cancer Institute, Inc. | Inhibitors of cyclin-dependent kinase 7 and uses thereof |
| CA3147422A1 (en) * | 2019-07-17 | 2021-01-21 | Kinnate Biopharma Inc. | Inhibitors of cyclin-dependent kinases |
| US12084453B2 (en) | 2021-12-10 | 2024-09-10 | Incyte Corporation | Bicyclic amines as CDK12 inhibitors |
| CN120661695B (zh) * | 2025-06-20 | 2026-03-20 | 山东大学齐鲁第二医院 | 联合上调snrk基因与gsk3b基因表达水平在制备抗非小细胞肺癌药物中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007123892A2 (en) | 2006-04-17 | 2007-11-01 | Arqule Inc. | Raf inhibitors and their uses |
| WO2010144416A1 (en) | 2009-06-08 | 2010-12-16 | Gaeta Federico C A | SUBSTITUTED PYRAZOLO [1,5-a] PYRIDINE COMPOUNDS HAVING MULTI-TARGET ACTIVITY |
| BR112013011520A2 (pt) * | 2010-11-19 | 2019-09-24 | Hoffmann La Roche | pirazolo piridinas e pirazolo piridinas e seu uso como inibidores de tyk2 |
| US9382239B2 (en) | 2011-11-17 | 2016-07-05 | Dana-Farber Cancer Institute, Inc. | Inhibitors of c-Jun-N-terminal kinase (JNK) |
| EP2909194A1 (en) | 2012-10-18 | 2015-08-26 | Dana-Farber Cancer Institute, Inc. | Inhibitors of cyclin-dependent kinase 7 (cdk7) |
| TWI621618B (zh) * | 2013-03-13 | 2018-04-21 | 比利時商健生藥品公司 | 經取代２－氮雜雙環類及其作為食慾素受體調控劑之用途 |
| WO2015058126A1 (en) | 2013-10-18 | 2015-04-23 | Syros Pharmaceuticals, Inc. | Heteroaromatic compounds useful for the treatment of prolferative diseases |
| EP3057956B1 (en) * | 2013-10-18 | 2021-05-05 | Dana-Farber Cancer Institute, Inc. | Polycyclic inhibitors of cyclin-dependent kinase 7 (cdk7) |
-
2019
- 2019-12-13 US US17/413,299 patent/US20220073512A1/en active Pending
- 2019-12-13 CN CN201980080949.8A patent/CN113164477A/zh active Pending
- 2019-12-13 EP EP19894946.3A patent/EP3893879A4/en active Pending
- 2019-12-13 AU AU2019395255A patent/AU2019395255B2/en active Active
- 2019-12-13 CA CA3115126A patent/CA3115126A1/en active Pending
- 2019-12-13 WO PCT/US2019/066201 patent/WO2020123925A1/en not_active Ceased
- 2019-12-13 JP JP2021533779A patent/JP7642540B2/ja active Active
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