JP2022512922A5 - - Google Patents

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Publication number
JP2022512922A5
JP2022512922A5 JP2021524069A JP2021524069A JP2022512922A5 JP 2022512922 A5 JP2022512922 A5 JP 2022512922A5 JP 2021524069 A JP2021524069 A JP 2021524069A JP 2021524069 A JP2021524069 A JP 2021524069A JP 2022512922 A5 JP2022512922 A5 JP 2022512922A5
Authority
JP
Japan
Prior art keywords
seq
amino acid
acid sequence
transmembrane domain
car
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021524069A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022512922A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/060005 external-priority patent/WO2020097164A1/en
Publication of JP2022512922A publication Critical patent/JP2022512922A/ja
Publication of JP2022512922A5 publication Critical patent/JP2022512922A5/ja
Pending legal-status Critical Current

Links

JP2021524069A 2018-11-06 2019-11-06 キメラ抗原受容体記憶様(carml)nk細胞ならびにその産生および使用方法 Pending JP2022512922A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862756294P 2018-11-06 2018-11-06
US62/756,294 2018-11-06
US201962788440P 2019-01-04 2019-01-04
US62/788,440 2019-01-04
PCT/US2019/060005 WO2020097164A1 (en) 2018-11-06 2019-11-06 Chimeric antigen receptor memory-like (carml) nk cells and methods of making and using same

Publications (2)

Publication Number Publication Date
JP2022512922A JP2022512922A (ja) 2022-02-07
JP2022512922A5 true JP2022512922A5 (https=) 2022-11-14

Family

ID=70612473

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021524069A Pending JP2022512922A (ja) 2018-11-06 2019-11-06 キメラ抗原受容体記憶様(carml)nk細胞ならびにその産生および使用方法

Country Status (10)

Country Link
US (1) US20220073585A1 (https=)
EP (1) EP3876961A4 (https=)
JP (1) JP2022512922A (https=)
KR (1) KR20210090220A (https=)
CN (1) CN113423409A (https=)
AU (1) AU2019377461A1 (https=)
CA (1) CA3117206A1 (https=)
IL (1) IL282850A (https=)
SG (1) SG11202104287RA (https=)
WO (1) WO2020097164A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3120563A1 (en) 2018-11-26 2020-06-04 Nkarta, Inc. Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
EP3773918A4 (en) 2019-03-05 2022-01-05 Nkarta, Inc. CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY
US11459372B2 (en) 2020-11-30 2022-10-04 Crispr Therapeutics Ag Gene-edited natural killer cells
WO2022144632A1 (en) 2020-12-30 2022-07-07 Crispr Therapeutics Ag Compositions and methods for differentiating stem cells into nk cells
JP2024504728A (ja) * 2021-01-26 2024-02-01 サイトケアズ (シャンハイ) インコーポレイテッド キメラ抗原受容体(car)構築物およびcar構築物を発現するnk細胞
WO2022171179A1 (zh) * 2021-02-10 2022-08-18 苏州克睿基因生物科技有限公司 一种扩增增强子及其应用
US20230330228A1 (en) 2022-03-22 2023-10-19 WUGEN, Inc. Hybrid promoters, vectors containing same and methods of use

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130266551A1 (en) * 2003-11-05 2013-10-10 St. Jude Children's Research Hospital, Inc. Chimeric receptors with 4-1bb stimulatory signaling domain
CN103946952A (zh) * 2011-09-16 2014-07-23 宾夕法尼亚大学董事会 用于治疗癌症的rna改造的t细胞
EP2948544A4 (en) * 2013-01-28 2016-08-03 St Jude Childrens Res Hospital CHIMERIC RECEPTOR WITH NKG2D SPECIFICITY FOR CELL THERAPY AGAINST CANCER AND INFECTION DISEASES
AU2015244039B2 (en) * 2014-04-07 2021-10-21 Novartis Ag Treatment of cancer using anti-CD19 chimeric antigen receptor
BR112017001183A2 (pt) * 2014-07-21 2017-11-28 Novartis Ag tratamento de câncer usando receptor de antígeno quimérico anti-bcma humanizado
BR112017005631A2 (pt) * 2014-09-19 2018-06-26 City Of Hope células t com receptor de antígeno coestimulador quimérico direcionadas à il13ra2
JP6849600B6 (ja) * 2015-01-29 2021-06-30 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ キメラ抗原受容体、組成物及び方法
EP3548049A4 (en) * 2016-12-05 2020-07-22 Fate Therapeutics, Inc. COMPOSITIONS AND METHODS FOR MODULATION OF IMMUNE CELLS IN ADOPTIVE IMMUNOTHERAPIES
CA3057838A1 (en) * 2017-03-24 2018-09-27 Lentigen Technology, Inc. Compositions and methods for treating cancer with anti-cd33 immunotherapy
US11771718B2 (en) * 2017-10-18 2023-10-03 Precigen, Inc. Polypeptide compositions comprising spacers
CN108219004A (zh) * 2018-02-08 2018-06-29 吉林省拓华生物科技有限公司 双特异嵌合抗原受体修饰的t细胞、其制备方法及用途
EP4021485A1 (en) * 2019-08-28 2022-07-06 King's College London B cell targeted parallel car (pcar) therapeutic agents

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