JP2022511498A5 - - Google Patents

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Publication number
JP2022511498A5
JP2022511498A5 JP2021531818A JP2021531818A JP2022511498A5 JP 2022511498 A5 JP2022511498 A5 JP 2022511498A5 JP 2021531818 A JP2021531818 A JP 2021531818A JP 2021531818 A JP2021531818 A JP 2021531818A JP 2022511498 A5 JP2022511498 A5 JP 2022511498A5
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JP
Japan
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JP2021531818A
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Japanese (ja)
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JP7504097B2 (ja
JP2022511498A (ja
JPWO2020118213A5 (https=
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Priority claimed from PCT/US2019/065005 external-priority patent/WO2020118213A1/en
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Publication of JPWO2020118213A5 publication Critical patent/JPWO2020118213A5/ja
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JP2021531818A 2018-12-06 2019-12-06 Cdk4/6阻害剤に耐性の癌を治療するための方法 Active JP7504097B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862776323P 2018-12-06 2018-12-06
US62/776,323 2018-12-06
PCT/US2019/065005 WO2020118213A1 (en) 2018-12-06 2019-12-06 Methods for treating cancer resistant to cdk4/6 inhibitors

Publications (4)

Publication Number Publication Date
JP2022511498A JP2022511498A (ja) 2022-01-31
JP2022511498A5 true JP2022511498A5 (https=) 2022-12-19
JPWO2020118213A5 JPWO2020118213A5 (https=) 2022-12-19
JP7504097B2 JP7504097B2 (ja) 2024-06-21

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ID=69063871

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JP2021531818A Active JP7504097B2 (ja) 2018-12-06 2019-12-06 Cdk4/6阻害剤に耐性の癌を治療するための方法

Country Status (17)

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US (2) US20210330612A1 (https=)
EP (1) EP3890834A1 (https=)
JP (1) JP7504097B2 (https=)
KR (1) KR20210100137A (https=)
CN (2) CN113164779A (https=)
AU (1) AU2019395093B2 (https=)
BR (1) BR112021010110A2 (https=)
CA (1) CA3121930A1 (https=)
EA (1) EA202191283A1 (https=)
IL (1) IL283659A (https=)
JO (1) JOP20210137B1 (https=)
MA (1) MA54388A (https=)
MX (1) MX2021006411A (https=)
PH (1) PH12021551319A1 (https=)
SG (1) SG11202105531XA (https=)
UA (1) UA130036C2 (https=)
WO (1) WO2020118213A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102674902B1 (ko) 2016-12-01 2024-06-14 아비나스 오퍼레이션스, 인코포레이티드 에스트로겐 수용체 분해제로서의 테트라히드로나프탈렌 및 테트라히드로이소퀴놀린 유도체
IL320609A (en) 2019-08-26 2025-07-01 Arvinas Operations Inc Methods for treating breast cancer with a history of tetrahydronaphthalene as estrogen receptor-disrupting agents
CN116744925A (zh) * 2020-12-14 2023-09-12 阿尔维纳斯运营股份有限公司 用四氢萘衍生物作为雌激素受体降解剂治疗乳腺癌的方法
GB202116745D0 (en) * 2021-11-19 2022-01-05 Institute Of Cancer Res Royal Cancer Hospital Prognostic and treatment response predictive method
CN115369089A (zh) * 2022-08-11 2022-11-22 中山大学孙逸仙纪念医院 两种er阳性her-2阴性乳腺癌cdk4/6抑制剂耐药株及其构建方法和用途
CN116327894A (zh) * 2023-04-10 2023-06-27 上海市第一妇婴保健院 一种治疗kras突变的卵巢癌的组合药物及其应用
WO2025202871A1 (en) * 2024-03-27 2025-10-02 Pfizer Inc. Methods for identifying biomarkers of treatment response and use thereof with a cdk4 inhibitor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9421264B2 (en) * 2014-03-28 2016-08-23 Duke University Method of treating cancer using selective estrogen receptor modulators
JP7019422B2 (ja) * 2015-04-29 2022-02-15 ラジウス ファーマシューティカルズ,インコーポレイテッド 癌を治療するための方法
KR102707399B1 (ko) * 2017-01-05 2024-09-13 래디어스 파마슈티컬스, 인코포레이티드 Rad1901-2hcl의 다형 형태
IL279853B2 (en) * 2018-07-04 2025-01-01 Radius Pharmaceuticals Inc Polymorphic forms of RAD 1901-2HCL

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