JP2022511394A5 - - Google Patents

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Publication number
JP2022511394A5
JP2022511394A5 JP2021517792A JP2021517792A JP2022511394A5 JP 2022511394 A5 JP2022511394 A5 JP 2022511394A5 JP 2021517792 A JP2021517792 A JP 2021517792A JP 2021517792 A JP2021517792 A JP 2021517792A JP 2022511394 A5 JP2022511394 A5 JP 2022511394A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
dose
variable region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021517792A
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English (en)
Japanese (ja)
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JP2022511394A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/CN2019/109214 external-priority patent/WO2020063988A1/zh
Publication of JP2022511394A publication Critical patent/JP2022511394A/ja
Publication of JP2022511394A5 publication Critical patent/JP2022511394A5/ja
Pending legal-status Critical Current

Links

JP2021517792A 2018-09-30 2019-09-29 Cldn18の抗体及び化学療法薬の併用療法 Pending JP2022511394A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN201811159863.8 2018-09-30
CN201811159863 2018-09-30
CN201811224605.3 2018-10-19
CN201811224605 2018-10-19
PCT/CN2019/109214 WO2020063988A1 (zh) 2018-09-30 2019-09-29 Cldn18的抗体和化疗药物的联合治疗

Publications (2)

Publication Number Publication Date
JP2022511394A JP2022511394A (ja) 2022-01-31
JP2022511394A5 true JP2022511394A5 (https=) 2022-10-07

Family

ID=69950365

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021517792A Pending JP2022511394A (ja) 2018-09-30 2019-09-29 Cldn18の抗体及び化学療法薬の併用療法

Country Status (6)

Country Link
US (1) US20220033491A1 (https=)
EP (1) EP3858384A4 (https=)
JP (1) JP2022511394A (https=)
KR (1) KR20210072027A (https=)
CN (1) CN112888458B (https=)
WO (1) WO2020063988A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2979068T3 (es) * 2016-07-08 2024-09-24 Crage Medical Co Ltd Anticuerpos para anti-claudina 18A2 y utilización de los mismos
WO2022122709A1 (en) 2020-12-07 2022-06-16 Sotio Biotech A.S. Antibody-drug conjugates based on humanized cldn18.2 antibodies
CN114634566B (zh) * 2020-12-16 2023-09-19 广州百暨基因科技有限公司 一种抗Claudin18_2的抗原结合片段、抗体及其应用
TW202241519A (zh) 2020-12-23 2022-11-01 捷克商舒迪安生物技術公司 腫瘤特異性密連蛋白18﹒2抗體藥物結合物
WO2022206975A1 (zh) * 2021-04-02 2022-10-06 原启生物科技(上海)有限责任公司 Cldn18.2抗原结合蛋白及其用途
JP2024540062A (ja) * 2021-11-05 2024-10-31 チア タイ ティエンチン ファーマシューティカル グループ カンパニー リミテッド 抗cldn18.2抗体及びその用途
TW202434307A (zh) 2023-01-18 2024-09-01 大陸商泰勵生物科技(上海)有限公司 抗體偶聯藥物及其用途
CN121620529A (zh) * 2023-07-31 2026-03-06 南京传奇生物科技有限公司 嵌合细胞因子受体及其使用方法
WO2025078686A1 (en) 2023-10-12 2025-04-17 Sotio Biotech A.S. Combination therapy involving antibody-drug conjugates against claudin18.2 and pd1/pd-l axis inhibitors for treatment of cancer
WO2025082356A1 (zh) * 2023-10-16 2025-04-24 江苏奥赛康生物医药有限公司 Cldn18_2抗体与化学治疗药物的组合及其应用
CN117430708B (zh) * 2023-12-21 2024-04-09 苏州近岸蛋白质科技股份有限公司 一种抗Claudin18.2抗体
CN118620072A (zh) * 2023-12-27 2024-09-10 上海博钒生物科技有限公司 一种肺炎克雷伯菌多糖单克隆抗体、其杂交瘤细胞株及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101602808B (zh) 2008-06-12 2012-06-20 上海市肿瘤研究所 特异性结合蛋白及其使用
WO2013167153A1 (en) * 2012-05-09 2013-11-14 Ganymed Pharmaceuticals Ag Antibodies useful in cancer diagnosis
EP3791896B1 (en) 2012-05-23 2024-01-10 Astellas Pharma Inc. Combination therapy involving antibodies against claudin 18.2 for treatment of cancer
EP2852409B1 (en) * 2012-05-23 2020-03-25 Astellas Pharma Inc. Combination therapy involving antibodies against claudin 18.2 for treatment of cancer
WO2013174404A1 (en) * 2012-05-23 2013-11-28 Ganymed Pharmaceuticals Ag Combination therapy involving antibodies against claudin 18.2 for treatment of cancer
WO2013174403A1 (en) * 2012-05-23 2013-11-28 Ganymed Pharmaceuticals Ag Combination therapy involving antibodies against claudin 18.2 for treatment of cancer
WO2014127785A1 (en) * 2013-02-20 2014-08-28 Ganymed Pharmaceuticals Ag Combination therapy involving antibodies against claudin 18.2 for treatment of cancer
WO2014146672A1 (en) * 2013-03-18 2014-09-25 Ganymed Pharmaceuticals Ag Therapy involving antibodies against claudin 18.2 for treatment of cancer
US10858415B2 (en) * 2014-01-29 2020-12-08 Tron—Translationale Onkologie An Der Universitatsmedizin Der Johannes Guttenberg-Universitat Mainz Gemeinnuizige Gmbh Peptide mimotopes of claudin 18.2 and uses thereof
ES2979068T3 (es) * 2016-07-08 2024-09-24 Crage Medical Co Ltd Anticuerpos para anti-claudina 18A2 y utilización de los mismos

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