JP2017515843A5 - - Google Patents

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Publication number
JP2017515843A5
JP2017515843A5 JP2016567491A JP2016567491A JP2017515843A5 JP 2017515843 A5 JP2017515843 A5 JP 2017515843A5 JP 2016567491 A JP2016567491 A JP 2016567491A JP 2016567491 A JP2016567491 A JP 2016567491A JP 2017515843 A5 JP2017515843 A5 JP 2017515843A5
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JP
Japan
Prior art keywords
composition
administered
dose
rate
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2016567491A
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English (en)
Japanese (ja)
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JP2017515843A (ja
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Publication date
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Priority claimed from PCT/US2015/030870 external-priority patent/WO2015175827A1/en
Publication of JP2017515843A publication Critical patent/JP2017515843A/ja
Publication of JP2017515843A5 publication Critical patent/JP2017515843A5/ja
Withdrawn legal-status Critical Current

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JP2016567491A 2014-05-14 2015-05-14 抗egfr治療薬の投与量および投与 Withdrawn JP2017515843A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461996819P 2014-05-14 2014-05-14
US61/996,819 2014-05-14
US201462005401P 2014-05-30 2014-05-30
US62/005,401 2014-05-30
PCT/US2015/030870 WO2015175827A1 (en) 2014-05-14 2015-05-14 Dosage and administration anti-egfr therapeutics

Publications (2)

Publication Number Publication Date
JP2017515843A JP2017515843A (ja) 2017-06-15
JP2017515843A5 true JP2017515843A5 (https=) 2018-06-21

Family

ID=53366255

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016567491A Withdrawn JP2017515843A (ja) 2014-05-14 2015-05-14 抗egfr治療薬の投与量および投与

Country Status (8)

Country Link
US (4) US9657108B2 (https=)
EP (1) EP3074422A1 (https=)
JP (1) JP2017515843A (https=)
KR (1) KR20170002600A (https=)
AU (1) AU2015259019A1 (https=)
HK (1) HK1223630A1 (https=)
MA (1) MA39599A (https=)
WO (1) WO2015175827A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8691231B2 (en) 2011-06-03 2014-04-08 Merrimack Pharmaceuticals, Inc. Methods of treatment of tumors expressing predominantly high affinity EGFR ligands or tumors expressing predominantly low affinity EGFR ligands with monoclonal and oligoclonal anti-EGFR antibodies
MA39599A (fr) 2014-05-14 2016-10-05 Merrimack Pharmaceuticals Inc Dosage et administration d'agents thérapeutiques anti-egfr
WO2017172678A1 (en) * 2016-03-30 2017-10-05 Merrimack Pharmaceuticals, Inc. Methods for treating cancer using combination therapies comprising an oligoclonal anti-egfr antibody preparation and lipsomal irinotecan
KR20180123265A (ko) * 2017-05-08 2018-11-16 에스케이하이닉스 주식회사 메모리 시스템 및 메모리 시스템의 동작 방법

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101289511A (zh) 2000-04-11 2008-10-22 杰南技术公司 多价抗体及其应用
WO2002055106A2 (en) 2001-01-09 2002-07-18 Merck Patent Gmbh Combination therapy using receptor tyrosine kinase inhibitors and angiogenesis inhibitors
AU2003251597A1 (en) 2002-06-19 2004-01-06 Abgenix, Inc. Method for predicting response to epidermal growth factor receptor-directed therapy
ES2533963T3 (es) 2002-10-10 2015-04-16 Merck Patent Gmbh Composiciones farmacéuticas dirigidas a receptores Erb-B1
WO2005044858A1 (en) 2003-11-07 2005-05-19 Ablynx N.V. Camelidae single domain antibodies vhh directed against epidermal growth factor receptor and uses therefor
AU2003295598B2 (en) 2002-11-15 2009-12-24 Genomic Health, Inc. Gene expression profiling of EGFR positive cancer
US20050003403A1 (en) 2003-04-22 2005-01-06 Rossi Edmund A. Polyvalent protein complex
CA2928387A1 (en) 2004-05-03 2005-11-17 Merrimack Pharmaceuticals, Inc. Drug delivery liposomes containing anionic polyols or anionic sugars
US7498142B2 (en) 2006-01-31 2009-03-03 Yeda Research And Development Co., Ltd. Methods of identifying combinations of antibodies with an improved anti-tumor activity and compositions and methods using the antibodies
US8895295B2 (en) 2006-11-15 2014-11-25 Biofire Diagnostics, Llc High density self-contained biological analysis
TW200846362A (en) 2007-02-09 2008-12-01 Symphogen As A polyclonal antibody product
CN101675075B (zh) 2007-03-01 2014-06-18 西福根有限公司 重组抗表皮生长因子受体抗体组合物
EP2190878A1 (en) 2007-09-06 2010-06-02 Genmab A/S Novel methods and antibodies for treating cancer
US8691730B2 (en) 2007-09-14 2014-04-08 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
US8159931B2 (en) 2007-12-11 2012-04-17 Broadcom Corporation Orthogonal pilot code construction
JO2913B1 (en) 2008-02-20 2015-09-15 امجين إنك, Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
US8273534B2 (en) 2008-05-14 2012-09-25 Genomic Health, Inc. Predictors of patient response to treatment with EGF receptor inhibitors
UA104868C2 (uk) 2008-08-15 2014-03-25 Меррімак Фармасьютікалз, Інк. Спосіб лікування пацієнта, що має неопластичну пухлину, відповідно до спрогнозованої реакції
EP2561356B1 (en) 2010-04-18 2016-08-03 Yeda Research and Development Co. Ltd. MOLECULES AND METHODS OF USING SAME FOR TREATING ErbB/ErbB LIGANDS ASSOCIATED DISEASES
CN105153307A (zh) 2010-05-04 2015-12-16 梅里麦克制药股份有限公司 抗表皮生长因子受体(egfr)的抗体及其用途
WO2011140151A1 (en) 2010-05-04 2011-11-10 Dyax Corp. Antibodies against epidermal growth factor receptor (egfr)
SG192775A1 (en) 2011-03-15 2013-09-30 Merrimack Pharmaceuticals Inc Overcoming resistance to erbb pathway inhibitors
US8691231B2 (en) 2011-06-03 2014-04-08 Merrimack Pharmaceuticals, Inc. Methods of treatment of tumors expressing predominantly high affinity EGFR ligands or tumors expressing predominantly low affinity EGFR ligands with monoclonal and oligoclonal anti-EGFR antibodies
EP2554551A1 (en) 2011-08-03 2013-02-06 Fundacio Institut mar d'Investigacions Médiques (IMIM) Mutations in the epidermal growth factor receptor gene
AU2013201584A1 (en) 2012-03-12 2013-09-26 Merrimack Pharmaceuticals, Inc. Methods for treating pancreatic cancer using combination therapies comprising an anti-ErbB3 antibody
AU2013202947B2 (en) 2012-06-13 2016-06-02 Ipsen Biopharm Ltd. Methods for treating pancreatic cancer using combination therapies comprising liposomal irinotecan
MA39599A (fr) 2014-05-14 2016-10-05 Merrimack Pharmaceuticals Inc Dosage et administration d'agents thérapeutiques anti-egfr
WO2016172584A1 (en) 2015-04-24 2016-10-27 Merrimack Pharmaceuticals, Inc. Methods of treating patients having mutations in the extracellular domain of epidermal growth factor receptor (egfr) with a combination of three fully human monoclonal anti-egfr antibodies

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