JP2022509517A5 - - Google Patents

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Publication number
JP2022509517A5
JP2022509517A5 JP2021548539A JP2021548539A JP2022509517A5 JP 2022509517 A5 JP2022509517 A5 JP 2022509517A5 JP 2021548539 A JP2021548539 A JP 2021548539A JP 2021548539 A JP2021548539 A JP 2021548539A JP 2022509517 A5 JP2022509517 A5 JP 2022509517A5
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JP
Japan
Prior art keywords
mutations
seq
recombinant protein
antitrypsin
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021548539A
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English (en)
Japanese (ja)
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JP7731288B2 (ja
JP2022509517A (ja
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Priority claimed from PCT/US2019/058673 external-priority patent/WO2020092448A1/en
Publication of JP2022509517A publication Critical patent/JP2022509517A/ja
Publication of JP2022509517A5 publication Critical patent/JP2022509517A5/ja
Priority to JP2024103143A priority Critical patent/JP2024123234A/ja
Application granted granted Critical
Publication of JP7731288B2 publication Critical patent/JP7731288B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021548539A 2018-10-29 2019-10-29 アルファ－１－アンチトリプシン欠乏症のための組成物及び方法 Active JP7731288B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024103143A JP2024123234A (ja) 2018-10-29 2024-06-26 アルファ－１－アンチトリプシン欠乏症のための組成物及び方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862752182P 2018-10-29 2018-10-29
US62/752,182 2018-10-29
PCT/US2019/058673 WO2020092448A1 (en) 2018-10-29 2019-10-29 Compositions and methods for alpha-1-antitrypsin disorders

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024103143A Division JP2024123234A (ja) 2018-10-29 2024-06-26 アルファ－１－アンチトリプシン欠乏症のための組成物及び方法

Publications (3)

Publication Number Publication Date
JP2022509517A JP2022509517A (ja) 2022-01-20
JP2022509517A5 true JP2022509517A5 (https=) 2022-11-08
JP7731288B2 JP7731288B2 (ja) 2025-08-29

Family

ID=68771752

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021548539A Active JP7731288B2 (ja) 2018-10-29 2019-10-29 アルファ－１－アンチトリプシン欠乏症のための組成物及び方法
JP2024103143A Pending JP2024123234A (ja) 2018-10-29 2024-06-26 アルファ－１－アンチトリプシン欠乏症のための組成物及び方法

Family Applications After (1)

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JP2024103143A Pending JP2024123234A (ja) 2018-10-29 2024-06-26 アルファ－１－アンチトリプシン欠乏症のための組成物及び方法

Country Status (9)

Country Link
US (2) US12497441B2 (https=)
EP (1) EP3873926A1 (https=)
JP (2) JP7731288B2 (https=)
KR (1) KR20210111245A (https=)
CN (1) CN113286816B (https=)
AU (1) AU2019369403B2 (https=)
BR (1) BR112021008200A2 (https=)
CA (1) CA3117961A1 (https=)
WO (1) WO2020092448A1 (https=)

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US20200385713A1 (en) 2019-01-22 2020-12-10 Korro Bio, Inc. Rna-editing oligonucleotides and uses thereof
CA3127243A1 (en) 2019-01-22 2020-07-30 Korro Bio, Inc. Rna-editing oligonucleotides and uses thereof
EP3914260A4 (en) 2019-01-22 2023-05-17 Korro Bio, Inc. RNA-EDITING OLIGONUCLEOTIDES AND THEIR USE
KR20230033651A (ko) * 2020-05-28 2023-03-08 코로 바이오, 인크. Serpina1의 adar-매개 편집을 위한 방법 및 조성물
AU2021375735A1 (en) * 2020-11-06 2023-06-08 Aatec Medical Gmbh A composition comprising extra-cellular vesicles from mesenchymal stem cells and alpha-1 antitrypsin for the treatment of viral infections
US20240101630A1 (en) * 2020-12-18 2024-03-28 Cullinan Amber Corp. Bi-functional linear fusion collagen-localized immunomodulatory molecules and methods thereof
CN117942275A (zh) * 2022-10-31 2024-04-30 康码（上海）生物科技有限公司 一种基于病毒阻断剂的洗手液及其应用
CN121100127A (zh) * 2023-05-05 2025-12-09 保罗·托马斯·金 新型治疗性多肽
EP4730999A1 (en) * 2023-06-22 2026-04-29 AATEC Medical GmbH Recombinant aat from yeast to treat transplants
EP4480493A1 (en) 2023-06-22 2024-12-25 AATEC Medical GmbH A recombinant human alpha-1 antitrypsin glycoprotein for treating non-viral inflammatory diseases of the lung

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DE122007000007I2 (de) 1986-04-09 2010-12-30 Genzyme Corp Genetisch transformierte Tiere, die ein gewünschtes Protein in Milch absondern
US4873316A (en) 1987-06-23 1989-10-10 Biogen, Inc. Isolation of exogenous recombinant proteins from the milk of transgenic mammals
GB8909916D0 (en) * 1989-04-29 1989-06-14 Delta Biotechnology Ltd Polypeptides
GB9404270D0 (en) 1994-03-05 1994-04-20 Delta Biotechnology Ltd Yeast strains and modified albumins
US6632637B1 (en) 1999-10-13 2003-10-14 Immunex Corporation Vectors and methods for recombinant protein expression
EP2213743A1 (en) 2000-04-12 2010-08-04 Human Genome Sciences, Inc. Albumin fusion proteins
WO2003066824A2 (en) 2002-02-07 2003-08-14 Aventis Behring Gmbh Albumin-fused kunitz domain peptides
EP2287326A1 (en) 2003-08-08 2011-02-23 Arriva Pharmaceuticals, Inc. Methods of protein production in yeast
US20070269442A1 (en) 2006-05-19 2007-11-22 Robert J. Webber Chimeric monoclonal antibody recognizing iNOS
AU2007293614A1 (en) 2006-09-08 2008-03-13 Ablynx N.V. Serum albumin binding proteins with long half-lives
WO2008086524A2 (en) 2007-01-11 2008-07-17 University Of Florida Research Foundation, Inc. Alpha-1-antitrypsin variants and uses thereof
KR100992526B1 (ko) 2007-11-21 2010-11-05 한국과학기술연구원 이황화결합을 이용한 내열성의 알파-1-안티트립신 뮤테인및 그의 제조방법
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AU2012275295B2 (en) * 2011-06-28 2016-11-10 Inhibrx, Lp WAP domain fusion polypeptides and methods of use thereof
KR102231139B1 (ko) 2011-06-28 2021-03-24 인히브릭스, 인크. 세르핀 융합 폴리펩타이드 및 이의 이용 방법
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CN110092828B (zh) 2018-01-31 2021-08-24 北京大学 重组突变体α1-抗胰蛋白酶及其制备和应用

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