JP2022506761A5 - - Google Patents

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Publication number
JP2022506761A5
JP2022506761A5 JP2021524345A JP2021524345A JP2022506761A5 JP 2022506761 A5 JP2022506761 A5 JP 2022506761A5 JP 2021524345 A JP2021524345 A JP 2021524345A JP 2021524345 A JP2021524345 A JP 2021524345A JP 2022506761 A5 JP2022506761 A5 JP 2022506761A5
Authority
JP
Japan
Prior art keywords
antibody construct
item
seq
heavy chain
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021524345A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022506761A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/058648 external-priority patent/WO2020092427A1/en
Publication of JP2022506761A publication Critical patent/JP2022506761A/ja
Publication of JP2022506761A5 publication Critical patent/JP2022506761A5/ja
Priority to JP2024144789A priority Critical patent/JP2024170456A/ja
Pending legal-status Critical Current

Links

JP2021524345A 2018-10-29 2019-10-29 IgA抗体構築物を含む組成物および方法 Pending JP2022506761A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024144789A JP2024170456A (ja) 2018-10-29 2024-08-26 IgA抗体構築物を含む組成物および方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP18203183 2018-10-29
US201862752641P 2018-10-30 2018-10-30
US62/752,641 2018-10-30
PCT/US2019/058648 WO2020092427A1 (en) 2018-10-29 2019-10-29 COMPOSITIONS AND METHODS COMPRISING IgA ANTIBODY CONSTRUCTS
EP18203183.1 2019-10-29

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024144789A Division JP2024170456A (ja) 2018-10-29 2024-08-26 IgA抗体構築物を含む組成物および方法

Publications (2)

Publication Number Publication Date
JP2022506761A JP2022506761A (ja) 2022-01-17
JP2022506761A5 true JP2022506761A5 (https=) 2022-10-31

Family

ID=70462698

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021524345A Pending JP2022506761A (ja) 2018-10-29 2019-10-29 IgA抗体構築物を含む組成物および方法
JP2024144789A Pending JP2024170456A (ja) 2018-10-29 2024-08-26 IgA抗体構築物を含む組成物および方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024144789A Pending JP2024170456A (ja) 2018-10-29 2024-08-26 IgA抗体構築物を含む組成物および方法

Country Status (9)

Country Link
US (1) US20210332131A1 (https=)
EP (1) EP3873942A4 (https=)
JP (2) JP2022506761A (https=)
KR (1) KR20210096612A (https=)
CN (1) CN113260632A (https=)
AU (1) AU2019369397A1 (https=)
CA (1) CA3118312A1 (https=)
GB (1) GB2596411B (https=)
WO (1) WO2020092427A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114096559B (zh) * 2019-03-27 2026-03-20 蒂嘉特克斯公司 工程化iga抗体及其使用方法
WO2022087416A1 (en) * 2020-10-22 2022-04-28 Actinium Pharmaceuticals, Inc. Combination radioimmunotherapy and cd47 blockade in the treatment of cancer
WO2022125439A2 (en) * 2020-12-07 2022-06-16 The Regents Of The University Of California Innate immune cell silencing by sirp-alpha engager
CN116731161A (zh) * 2021-09-18 2023-09-12 南开大学 工程化IgG和IgA嵌合的“四叶草型X抗体”
AU2023219697A1 (en) * 2022-02-09 2024-08-22 Exelixis, Inc. Multispecific binding agents and uses thereof.

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0226878D0 (en) * 2002-11-18 2002-12-24 Univ Warwick Antibodies
US9296820B2 (en) * 2003-11-05 2016-03-29 Roche Glycart Ag Polynucleotides encoding anti-CD20 antigen binding molecules with increased Fc receptor binding affinity and effector function
US20090215992A1 (en) * 2005-08-19 2009-08-27 Chengbin Wu Dual variable domain immunoglobulin and uses thereof
CA2737241C (en) * 2008-09-26 2017-08-29 Ucb Pharma S.A. Multivalent antibody fusion proteins
CA2771336C (en) * 2009-09-15 2019-11-26 The Board Of Trustees Of The Leland Stanford Junior University Synergistic anti-cd47 therapy for hematologic cancers
EP2791170A1 (en) * 2011-12-16 2014-10-22 Synthon Biopharmaceuticals B.V. Compounds and methods for treating inflammatory diseases
DK3725807T3 (da) * 2012-12-03 2026-01-12 Novimmune Sa Anti-cd47 antistoffer og fremgangsmåder til anvendelse deraf
US20140213771A1 (en) * 2012-12-28 2014-07-31 Abbvie, Inc. Multi-specific binding proteins
JP2016514676A (ja) * 2013-03-15 2016-05-23 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung 四価二重特異性抗体
US10519251B2 (en) * 2013-12-30 2019-12-31 Epimab Biotherapeutics, Inc. Fabs-in-tandem immunoglobulin and uses thereof
WO2016022971A1 (en) * 2014-08-08 2016-02-11 The Board Of Trustees Of The Leland Stanford Junior University Sirp alpha-antibody fusion proteins
PL3180363T3 (pl) * 2014-08-15 2020-02-28 Merck Patent Gmbh Białka fuzyjne immunoglobulin sirp-alfa
WO2017053423A1 (en) * 2015-09-21 2017-03-30 Erasmus University Medical Center Anti-cd47 antibodies and methods of use
CN107459579B (zh) * 2016-06-01 2021-09-24 泰州迈博太科药业有限公司 一种靶向egfr和cd47双特异性融合蛋白、制备方法及应用
CA3035427A1 (en) * 2016-09-01 2018-03-08 Umc Utrecht Holding B.V. Cd20 antibodies
WO2018137705A1 (en) * 2017-01-26 2018-08-02 Zai Lab (Shanghai) Co., Ltd. Cd47 antigen binding unit and uses thereof
EP3747438A1 (en) * 2017-07-24 2020-12-09 Stichting Het Nederlands Kanker Instituut- Antoni van Leeuwenhoek Ziekenhuis Treating pathological conditions by direct and indirect targeting of sirpa - cd47 interaction
IL272418B2 (en) * 2017-08-08 2024-09-01 Hoffmann La Roche Abinotuzumab treatment of a new subgroup of DLBCL patients

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