JP2022506716A - 抵抗性高血圧に対する併用療法 - Google Patents

抵抗性高血圧に対する併用療法 Download PDF

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Publication number
JP2022506716A
JP2022506716A JP2021524278A JP2021524278A JP2022506716A JP 2022506716 A JP2022506716 A JP 2022506716A JP 2021524278 A JP2021524278 A JP 2021524278A JP 2021524278 A JP2021524278 A JP 2021524278A JP 2022506716 A JP2022506716 A JP 2022506716A
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JP
Japan
Prior art keywords
manp
polypeptide
diuretic
administered
mammal
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Pending
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JP2021524278A
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English (en)
Japanese (ja)
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JP2022506716A5 (https=
Inventor
シー． バーネット，ジュニア，ジョン
ジュガシヴィリ，ニーナ
Original Assignee
メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ
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Publication of JP2022506716A publication Critical patent/JP2022506716A/ja
Publication of JP2022506716A5 publication Critical patent/JP2022506716A5/ja
Priority to JP2024111406A priority Critical patent/JP2024156691A/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2242—Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2021524278A 2018-11-09 2019-11-08 抵抗性高血圧に対する併用療法 Pending JP2022506716A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024111406A JP2024156691A (ja) 2018-11-09 2024-07-11 抵抗性高血圧に対する併用療法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862758009P 2018-11-09 2018-11-09
US62/758,009 2018-11-09
PCT/US2019/060401 WO2020097421A1 (en) 2018-11-09 2019-11-08 Combination treatment for resistant hypertension

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024111406A Division JP2024156691A (ja) 2018-11-09 2024-07-11 抵抗性高血圧に対する併用療法

Publications (2)

Publication Number Publication Date
JP2022506716A true JP2022506716A (ja) 2022-01-17
JP2022506716A5 JP2022506716A5 (https=) 2022-11-17

Family

ID=70612496

Family Applications (2)

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JP2021524278A Pending JP2022506716A (ja) 2018-11-09 2019-11-08 抵抗性高血圧に対する併用療法
JP2024111406A Pending JP2024156691A (ja) 2018-11-09 2024-07-11 抵抗性高血圧に対する併用療法

Family Applications After (1)

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JP2024111406A Pending JP2024156691A (ja) 2018-11-09 2024-07-11 抵抗性高血圧に対する併用療法

Country Status (13)

Country Link
US (2) US20220118054A1 (https=)
EP (2) EP4603090A1 (https=)
JP (2) JP2022506716A (https=)
KR (1) KR20210090229A (https=)
CN (1) CN113727997A (https=)
AU (2) AU2019375988A1 (https=)
BR (1) BR112021008841A2 (https=)
CA (1) CA3119055A1 (https=)
ES (1) ES3047085T3 (https=)
IL (2) IL282958B2 (https=)
MX (1) MX2021005453A (https=)
PL (1) PL3877402T3 (https=)
WO (1) WO2020097421A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240369535A1 (en) * 2021-09-07 2024-11-07 Mayo Foundation For Medical Education And Research METHODS AND MATERIALS FOR DETERMINING pGC TARGET DOSAGE
WO2023039453A2 (en) * 2021-09-09 2023-03-16 Mayo Foundation For Medical Education And Research Dual-function polypeptides and methods for use thereof
US20240116990A1 (en) * 2022-09-19 2024-04-11 Mayo Foundation For Medical Education And Research Compositions and Methods of Treatment Using CRRL 191
KR20250150650A (ko) * 2023-02-22 2025-10-20 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 Manp를 이용한 대사증후군을 동반한 고혈압 치료 방법
US12427185B2 (en) 2023-09-05 2025-09-30 E-Star Biotech, LLC Formulations of MANP and uses thereof
WO2025184377A1 (en) * 2024-02-28 2025-09-04 Mayo Foundation For Medical Education And Research Methods for sustained lowering of blood pressure using manp

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170020899A1 (en) * 2014-03-14 2017-01-26 Madeleine Pharmaceuticals Pty Ltd Adjuvant therapy to standard of care (soc) diuretic treatment
WO2018089601A1 (en) * 2016-11-09 2018-05-17 Mayo Foundation For Medical Education And Research Manp analogues

Family Cites Families (20)

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US4161521A (en) 1975-08-08 1979-07-17 Merck & Co., Inc. Somatostatin analogs
NO812612L (no) 1980-08-06 1982-02-08 Ferring Pharma Ltd Enzym-inhibitorer.
JP2551756B2 (ja) 1985-05-07 1996-11-06 武田薬品工業株式会社 ポリオキシカルボン酸エステルおよびその製造法
US4757048A (en) 1985-11-05 1988-07-12 Biotechnology Research Associates J.V. Synthetic analogs of atrial natriuretic peptides
US6312679B1 (en) 1986-08-18 2001-11-06 The Dow Chemical Company Dense star polymer conjugates as dyes
US4935492A (en) 1987-12-24 1990-06-19 California Biotechnology Inc. Cyclic analogs of atrial natriuretic peptides
US4938763B1 (en) 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
DE4004430A1 (de) 1990-02-09 1991-08-14 Schering Ag Aus polyaldehyden aufgebaute kontrastmittel
KR930009516B1 (ko) 1990-04-27 1993-10-06 미쓰비시덴키 가부시키가이샤 진동검출기 및 그의 고유진동주파수 조정방법
US5410016A (en) 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US5529914A (en) 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
US5698213A (en) 1995-03-06 1997-12-16 Ethicon, Inc. Hydrogels of absorbable polyoxaesters
US6410044B1 (en) 1998-03-19 2002-06-25 Surmodics, Inc. Crosslinkable macromers
US6969480B2 (en) 2000-05-12 2005-11-29 Matregen Corp. Method of producing structures using centrifugal forces
WO2004047871A2 (en) 2002-11-26 2004-06-10 Nobex Corporation Modified naturetic compounds, conjugates, and uses thereof
DE602005013244D1 (de) 2004-08-12 2009-04-23 Quest Pharmaceutical Services Pharmazeutische zusammensetzungen für die kontroll
WO2008061355A1 (en) 2006-11-24 2008-05-29 Matregen Corp. Glp-1 depot systems, and methods of manufacture and uses thereof
US20100266704A1 (en) 2008-12-15 2010-10-21 Novartis Ag Octreotide depot formulation with constantly high exposure levels

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170020899A1 (en) * 2014-03-14 2017-01-26 Madeleine Pharmaceuticals Pty Ltd Adjuvant therapy to standard of care (soc) diuretic treatment
WO2018089601A1 (en) * 2016-11-09 2018-05-17 Mayo Foundation For Medical Education And Research Manp analogues

Also Published As

Publication number Publication date
IL282958B2 (en) 2025-01-01
US20250381249A1 (en) 2025-12-18
KR20210090229A (ko) 2021-07-19
AU2019375988A1 (en) 2021-05-27
IL315007A (en) 2024-10-01
EP3877402B1 (en) 2025-07-16
WO2020097421A1 (en) 2020-05-14
CA3119055A1 (en) 2020-05-14
IL282958B1 (en) 2024-09-01
EP3877402A1 (en) 2021-09-15
ES3047085T3 (en) 2025-12-03
MX2021005453A (es) 2021-09-08
EP3877402A4 (en) 2022-07-27
JP2024156691A (ja) 2024-11-06
CN113727997A (zh) 2021-11-30
PL3877402T3 (pl) 2025-12-01
IL282958A (en) 2021-06-30
BR112021008841A2 (pt) 2021-08-31
AU2025203575A1 (en) 2025-06-05
EP4603090A1 (en) 2025-08-20
US20220118054A1 (en) 2022-04-21

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