JP2022504078A - 単一の生物学的サンプル由来のタンパク質、ヌクレオソームおよび無細胞核酸のシーケンシングベースの同時分析 - Google Patents

単一の生物学的サンプル由来のタンパク質、ヌクレオソームおよび無細胞核酸のシーケンシングベースの同時分析 Download PDF

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JP2022504078A
JP2022504078A JP2021518090A JP2021518090A JP2022504078A JP 2022504078 A JP2022504078 A JP 2022504078A JP 2021518090 A JP2021518090 A JP 2021518090A JP 2021518090 A JP2021518090 A JP 2021518090A JP 2022504078 A JP2022504078 A JP 2022504078A
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dna
adapter
nucleic acid
sample
sequence
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JPWO2020072829A5 (cg-RX-API-DMAC7.html
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パトリック エー． アレンスドルフ，
ダメク スペイセック，
クリストファー イー． エリソン，
サミュエル レヴィ，
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ブルースター ジェノミクス， インコーポレイテッド
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens

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JP2021518090A 2018-10-04 2019-10-03 単一の生物学的サンプル由来のタンパク質、ヌクレオソームおよび無細胞核酸のシーケンシングベースの同時分析 Pending JP2022504078A (ja)

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US201862741473P 2018-10-04 2018-10-04
US62/741,473 2018-10-04
PCT/US2019/054582 WO2020072829A2 (en) 2018-10-04 2019-10-03 Simultaneous, sequencing-based analysis of proteins, nucleosomes, and cell-free nucleic acids from a single biological sample

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JP2022504078A true JP2022504078A (ja) 2022-01-13
JPWO2020072829A5 JPWO2020072829A5 (cg-RX-API-DMAC7.html) 2022-10-04

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US (1) US20210380971A1 (cg-RX-API-DMAC7.html)
EP (1) EP3861132A2 (cg-RX-API-DMAC7.html)
JP (1) JP2022504078A (cg-RX-API-DMAC7.html)
CN (1) CN113166796A (cg-RX-API-DMAC7.html)
AU (1) AU2019354789A1 (cg-RX-API-DMAC7.html)
CA (1) CA3114606A1 (cg-RX-API-DMAC7.html)
MX (1) MX2021003847A (cg-RX-API-DMAC7.html)
SG (1) SG11202102954QA (cg-RX-API-DMAC7.html)
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CN113517026B (zh) * 2021-06-16 2022-08-19 苏州拉索生物芯片科技有限公司 应用于生物制品的标签序列的生成方法、系统、智能终端及计算机可读存储介质
WO2023288222A1 (en) * 2021-07-12 2023-01-19 The Trustees Of The University Of Pennsylvania Modified adapters for enzymatic dna deamination and methods of use thereof for epigenetic sequencing of free and immobilized dna
WO2023287876A1 (en) * 2021-07-15 2023-01-19 University Of Washington Efficient duplex sequencing using high fidelity next generation sequencing reads
EP4405496A4 (en) * 2021-09-23 2025-01-01 Genomic Testing Cooperative, LCA COMPOSITIONS AND METHODS FOR TARGETED NGS SEQUENCING OF CFRNA AND CFTNA
US20230086611A1 (en) * 2021-09-23 2023-03-23 Genomic Testing Cooperative, LCA Compositions and Methods for Targeted NGS Sequencing of cfRNA and cfTNA
WO2023097295A1 (en) * 2021-11-24 2023-06-01 Alida Biosciences, Inc. Rna and dna analysis using engineered surfaces
CN114934110A (zh) * 2022-06-15 2022-08-23 江西烈冰生物科技有限公司 用于获取基因表达的原始位置的生物芯片、试剂盒及方法
EP4623079A1 (en) * 2022-11-23 2025-10-01 Alida Biosciences, Inc. Chromatin profiling compositions and methods
CN116403645B (zh) * 2023-03-03 2024-01-09 阿里巴巴（中国）有限公司 转录因子结合位点的预测方法及装置

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WO2018031897A1 (en) * 2016-08-12 2018-02-15 Cdi Laboratories, Inc. Compositions and methods for analyzing nucleic acids associated with an analyte
WO2018041062A1 (zh) * 2016-08-29 2018-03-08 厦门艾德生物医药科技股份有限公司 一种用于检测基因突变的多定位双标签接头组及其制备方法和应用
JP2018514207A (ja) * 2015-04-28 2018-06-07 イラミーナ インコーポレーテッド 特異的分子インデックス（ｕｍｉ）を有する冗長リードを用いたシーケンシングｄｎａ断片におけるエラーの抑制

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EP3861132A2 (en) 2021-08-11
CA3114606A1 (en) 2020-04-09
US20210380971A1 (en) 2021-12-09
CN113166796A (zh) 2021-07-23
AU2019354789A1 (en) 2021-05-27
WO2020072829A3 (en) 2020-08-13
WO2020072829A2 (en) 2020-04-09
MX2021003847A (es) 2021-05-27
SG11202102954QA (en) 2021-04-29

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