JP2022502369A5 - - Google Patents

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Publication number
JP2022502369A5
JP2022502369A5 JP2021516452A JP2021516452A JP2022502369A5 JP 2022502369 A5 JP2022502369 A5 JP 2022502369A5 JP 2021516452 A JP2021516452 A JP 2021516452A JP 2021516452 A JP2021516452 A JP 2021516452A JP 2022502369 A5 JP2022502369 A5 JP 2022502369A5
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JP
Japan
Prior art keywords
cdr
sequence
seq
amino acid
acid sequence
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Application number
JP2021516452A
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English (en)
Japanese (ja)
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JP2022502369A (ja
JP7719713B2 (ja
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Priority claimed from PCT/CA2019/051434 external-priority patent/WO2020073121A1/en
Publication of JP2022502369A publication Critical patent/JP2022502369A/ja
Publication of JP2022502369A5 publication Critical patent/JP2022502369A5/ja
Application granted granted Critical
Publication of JP7719713B2 publication Critical patent/JP7719713B2/ja
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JP2021516452A 2018-10-07 2019-10-07 α-シヌクレインの立体配座特異的エピトープ、それに対する抗体、およびそれに関連する方法 Active JP7719713B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201862742408P 2018-10-07 2018-10-07
US62/742,408 2018-10-07
US201862780599P 2018-12-17 2018-12-17
US62/780,599 2018-12-17
US201962820701P 2019-03-19 2019-03-19
US62/820,701 2019-03-19
US201962864060P 2019-06-20 2019-06-20
US62/864,060 2019-06-20
PCT/CA2019/051434 WO2020073121A1 (en) 2018-10-07 2019-10-07 Conformation-specific epitopes in alpha-synuclein, antibodies thereto and methods related thereof

Publications (3)

Publication Number Publication Date
JP2022502369A JP2022502369A (ja) 2022-01-11
JP2022502369A5 true JP2022502369A5 (cg-RX-API-DMAC7.html) 2022-10-20
JP7719713B2 JP7719713B2 (ja) 2025-08-06

Family

ID=70163645

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021516452A Active JP7719713B2 (ja) 2018-10-07 2019-10-07 α-シヌクレインの立体配座特異的エピトープ、それに対する抗体、およびそれに関連する方法

Country Status (6)

Country Link
US (2) US12404321B2 (cg-RX-API-DMAC7.html)
EP (1) EP3861015A4 (cg-RX-API-DMAC7.html)
JP (1) JP7719713B2 (cg-RX-API-DMAC7.html)
AU (1) AU2019356804B2 (cg-RX-API-DMAC7.html)
CA (1) CA3148562A1 (cg-RX-API-DMAC7.html)
WO (1) WO2020073121A1 (cg-RX-API-DMAC7.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7136790B2 (ja) 2017-02-17 2022-09-13 ブリストル-マイヤーズ スクイブ カンパニー アルファ-シヌクレインに対する抗体およびその使用
WO2025236075A1 (en) * 2024-05-07 2025-11-20 The University Of British Columbia Immunogenic compositions for synucleinopathies

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7358331B2 (en) * 2003-05-19 2008-04-15 Elan Pharmaceuticals, Inc. Truncated fragments of alpha-synuclein in Lewy body disease
AT506535B1 (de) * 2008-02-22 2010-04-15 Affiris Forschungs & Entwicklungs Gmbh Vaccine enthaltend alpha-synuclein-mimotope auf basis von peptiden
US9045555B2 (en) 2008-07-01 2015-06-02 De Staat Der Nederlanden, Vert. Door De Minister Van Vws Vaccine against amyloid folding intermediate
CN102348720A (zh) * 2009-03-09 2012-02-08 雷蒙特亚特特拉维夫大学有限公司 预防和治疗神经退行性疾病的组合物和方法
CN102596236B (zh) * 2009-07-30 2015-06-24 辉瑞疫苗有限责任公司 抗原性Tau肽及其用途
EP2542571B1 (en) * 2010-03-03 2016-05-25 The University of British Columbia Oligomer-specific amyloid beta epitope and antibodies
CN102504016B (zh) * 2011-12-08 2014-05-28 清华大学 淀粉样蛋白纤维性寡聚体构象型抗原表位多肽及其应用
US9534044B2 (en) 2013-02-28 2017-01-03 United Arab Emirates University Alpha-synuclein antibodies and uses thereof
EP3374380A4 (en) 2015-11-09 2019-05-15 The University Of British Columbia C-terminal epitopes in amyloid-beta and conformation-sensitive antibodies
EP3448874A4 (en) 2016-04-29 2020-04-22 Voyager Therapeutics, Inc. COMPOSITIONS FOR TREATING A DISEASE
KR102550991B1 (ko) 2016-07-18 2023-07-04 더 유니버시티 오브 브리티쉬 콜롬비아 아밀로이드 베타에 대한 항체
US10364286B2 (en) * 2016-12-22 2019-07-30 H. Lundbeck A/S Monoclonal anti-alpha-synuclein antibodies for preventing tau aggregation

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